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Pupil can constrict without any input from brain

You've seen it on television: A doctor shines a bright light into an unconscious patient's eye to check for brain death. If the pupil constricts, the brain is OK, because in mammals, the brain controls the pupil. Or does it? Now, researchers at Johns Hopkins have discovered that in most mammals, in fact in most vertebrates, the pupil can constrict without any input from the brain.

3 Nov 2011

New laser technique could create tissue scaffolds, microneedles

In the emerging field of tissue engineering, scientists encourage cells to grow on carefully designed support scaffolds. The ultimate goal is to create living structures that might one day be used to replace lost or damaged tissue, but the manufacture of appropriately detailed scaffolds presents a significant challenge that has kept most tissue engineering applications confined to the research lab.

3 Nov 2011

Resveratrol holds key to reducing obesity and associated risks: Study

A new study shows that when taken regularly a natural compound known as resveratrol, found in red wine and grapes, mulberries and peanuts, can offer similar benefits to low-calorie diets and endurance training.

2 Nov 2011

Broader screening for hypertrophic cardiomyopathy

Around one in 500 Swedes carry a genetic mutation which can cause sudden cardiac death. The diagnosis can lead to major lifestyle changes, but quality of life can be maintained with the right advice and support, reveals a new study from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

2 Nov 2011

DJO Global third quarter net sales increase 12.7% to $263.1 million

DJO Global, Inc., a leading global provider of medical device solutions for musculoskeletal health, vascular health and pain management, today announced financial results for its operating subsidiary, DJO Finance LLC, for the third quarter of fiscal 2011, ended October 1, 2011.

2 Nov 2011

HRM curve analysis identifies patients at risk of MH

A new DNA test may make it much simpler to identify patients at risk of malignant hyperthermia (MH)—a rare but life-threatening complication of exposure to common anesthetics reports the November issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

2 Nov 2011

Young microenvironment rejuvenates old stem cells

Old stem cells can be rejuvenated by being placed in a young microenvironment, research from The University of Texas Health Science Center San Antonio shows. This raises the possibility that patients' own stem cells may one day be rescued and banked to treat their age-related diseases.

2 Nov 2011

Penn surgeons perform first bilateral hand transplantation

For the first time in the Delaware Valley Region, a patient has undergone a complex and intricate bilateral hand transplant that could significantly enhance the quality-of-life for persons with multiple limb loss.

2 Nov 2011

$Adiponectin linked to osteoporosis and increased risk of fractures$

Adiponectin linked to osteoporosis and increased risk of fractures

While obesity is a well-known cause of cardiovascular disease, research from the Sahlgrenska Academy at the University of Gothenburg, Sweden, has now revealed that the body's obesity hormones - adiponectin - are also linked to osteoporosis and an increased risk of fractures.

2 Nov 2011

Takeda receives FDA approval for VELCADE sNDA to treat MM

Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today announced that the U.S. Food and Drug Administration (FDA) has approved a supplemental new drug application (sNDA) for VELCADE (bortezomib) for Injection, which updates the label to include additional long-term overall survival (OS) data from the VISTA trial.

2 Nov 2011

Marathon recovery tips

More than 40,000 runners have spent the past several months training for the ING New York City Marathon. Once they have completed the race and achieved their goals, there are measures they can take to facilitate recovery, decrease post-race discomfort and return to running without injury. Eating immediately after the marathon, icing sore muscles, and having a gentle massage are only a few of the tips that Michael Silverman, PT, MSPT, physical therapist from the Rehabilitation Department at Hospital for Special Surgery in New York, offers runners who cross the finish line.

2 Nov 2011

Rigel reports net loss of $17.9 million for third quarter 2011

Rigel Pharmaceuticals, Inc. today reported financial results for the third quarter and nine months ended September 30, 2011.

1 Nov 2011

Scientists identify genetic mutation that causes rare childhood disease

An international collaboration of scientists, including researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health, has identified a genetic mutation that causes a rare childhood disease characterized predominantly by inflammation and fat loss.

1 Nov 2011

Heat, extreme exercise or febrile illness may also trigger MH

Malignant hyperthermia (MH) is a potentially life-threatening inherited disorder of muscle. Patients who are at risk for MH usually have no outward signs of muscle problems. However, when exposed to certain commonly used general anesthetics they may develop very high body temperature, increased heart rate and muscle breakdown. If not recognized and treated promptly MH may be fatal.

1 Nov 2011

Infiltration of white blood cells into blood vessels may explain high blood pressure in pregnancy

Virginia Commonwealth University School of Medicine researchers have discovered that the infiltration of white blood cells into an expectant mother's blood vessels may explain high blood pressure in pregnancy.

1 Nov 2011

Panel backs anthrax vaccine testing on children

An important panel of government advisers Friday recommended that the government should sponsor a controversial study to test the anthrax vaccine in children to see whether the inoculation would protect young Americans against a bioterrorist's attack.

31 Oct 2011

Leg muscle dysfunction related to severity of symptoms in heart failure patients

Doctors should not only treat the heart muscle in chronic heart failure patients, but also their leg muscles through exercise, say researchers in a study published today in the Journal of Applied Physiology.

31 Oct 2011

J&JPRD submits NUCYNTA ER sNDA to FDA for DPN associated neuropathic pain

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. announced today that it has submitted a supplemental New Drug Application to the U.S. Food and Drug Administration for NUCYNTA ER (tapentadol) extended-release tablets, an oral analgesic, for the management of neuropathic pain associated with diabetic peripheral neuropathy in adults.

31 Oct 2011

NALC's national bowling event to raise money for Muscular Dystrophy Association

Thousands of members of the National Association of Letter Carriers (NALC), an organization affiliated with the AFL-CIO, will head for scores of local bowling centers across the nation on Sunday, Nov. 6.

31 Oct 2011

Researchers shed light on inner workings of endocycle

An international team of researchers led by investigators in the U.S. and Germany has shed light on the inner workings of the endocycle, a common cell cycle that fuels growth in plants, animals and some human tissues and is responsible for generating up to half of the Earth's biomass.

31 Oct 2011