Aging News and Research

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A new technique to tag senescent cells

When it comes to treating disease, one promising avenue is addressing the presence of senescent cells. These cells - also known as "zombie cells" - stop dividing but don't die off as cells typically do.

27 Oct 2025

AI-powered app matches human-led programs in diabetes prevention

Researchers from Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health report that an AI-powered lifestyle intervention app for prediabetes reduced the risk of diabetes similarly to traditional, human-led programs in adults.

27 Oct 2025

Daily 40Hz audiovisual stimulation may slow cognitive decline in late-onset Alzheimer's patients

A new research paper documents the outcomes of five volunteers who continued to receive 40Hz light and sound stimulation for around two years after participating in an MIT early-stage clinical study of the potential Alzheimer's disease therapy.

27 Oct 2025

TRF1 protein depletion linked to leaner mice and altered metabolism

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

27 Oct 2025

Digital literacy and age-friendly employment opportunities can enhance well-being in older adults

Older adults face a high risk of isolation, especially after they retire. A recent study from the University of Georgia suggests smartphones, computers and tablets may help older adults stay connected.

27 Oct 2025

Scientists uncover excessive maturation and aging in the hippocampus

In a groundbreaking study, researchers at Fujita Health University and the Tokyo Metropolitan Institute of Medical Science have uncovered a previously overlooked form of brain abnormality linked to anxiety: excessive maturation and aging in the hippocampus, a state they term "hyper-maturity."

27 Oct 2025

Unlocking the secrets of vascular health through eye imaging

The tiny blood vessels in your eyes might hold the key to predicting a person's risk of developing heart disease and how fast they're biologically aging, according to researchers at McMaster University and Population Health Research Institute (PHRI) - a joint institute of Hamilton Health Sciences and McMaster.

24 Oct 2025

Unveiling the dual role of HIV integrase in viral replication

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain.

24 Oct 2025

Researchers map the complex sugar chains attached to rat serum proteins

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent variations with clear cell-type specificity.

24 Oct 2025

PAI-1 may be a promising therapeutic target for preventing age-related muscle and bone loss

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 11, 2025, titled "Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice."

23 Oct 2025

New York Regional Diabetes Research Center established with $10.8 million NIH grant

Albert Einstein College of Medicine has received a five-year, $10.8 million grant from the National Institutes of Health (NIH) to create the New York Regional Diabetes Research Center (NYR-DRC), a newly expanded multi-institutional center co-led with the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine.

23 Oct 2025

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

23 Oct 2025

When a hearing aid isn’t enough

Kitty Grutzmacher had contended with poor hearing for a decade, but the problem had worsened over the past year. Even with her hearing aids, "there was little or no sound," she said.

23 Oct 2025

Study sheds light on how aging unfolds in pets and humans

Scientists have long sought measurable signs in the body, called biomarkers, that reliably reveal our biological age or predict future health issues.

22 Oct 2025

Researchers gain new insights into aging based on studies in dogs

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.

22 Oct 2025

First-generation antihistamines increase delirium risk in older hospitalized patients

An analysis in the Journal of the American Geriatrics Society reveals that older inpatients admitted to physicians who prescribe higher amounts of first-generation antihistamines face an elevated risk of delirium while in the hospital.

22 Oct 2025

Scientists question the safety and efficacy of the diet for metabolic health

A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects of the ketogenic diet, raising important questions about its safety and efficacy for improving metabolic health.

22 Oct 2025

Report maps vaccination's comprehensive benefits for health and economy

A new Gerontological Society of America report, "Concentric Value of Vaccination: Intersecting Health, Economic, and Societal Benefits," provides evidence on the advantages of immunization for individual and population health, economic outcomes, and societal well-being.

22 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025