Biochemistry News and Research

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New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Discovery provides better understanding of retinal protein's structure and function

Scientists have discovered a mechanism by which an area of a protein shape-shifts to convert vitamin A into a form usable by the eye's light-sensing photoreceptor cells.

26 Oct 2022

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

Using a novel systems biology approach, scientists at University of California San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis (RA), a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.

24 Oct 2022

TANGO2 plays a role in heme homeostasis, research reveals

Heme, the iron-holding molecule that gives blood its red color, is essential for life. Yet, ironically, it can be quite toxic if not properly handled. In fact, numerous diseases – from various cancers to cardiovascular diseases – are associated with defects in heme homeostasis.

21 Oct 2022

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Pseudomonas aeruginosa (P.a.) are resistant to most antibiotics and cause life-threatening infections of wounds or the lungs.

21 Oct 2022

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Mitochondria - the organelles responsible for energy production in human cells - were once free-living organisms that found their way into early eukaryotic cells over a billion years ago.

20 Oct 2022

Nutrition education needed for all healthcare professionals to better support public health, research suggests

All healthcare professionals should study a curriculum of nutrition education during their studies in order to help better support public health - new paper suggests.

20 Oct 2022

Common oral bacterium promotes tumor progression-associated activity in pancreatic cancer cells

Virginia Tech researchers from the Department of Biomedical Engineering and Mechanics and the Department of Biochemistry have discovered a characteristic of a common oral bacterium that relocates to pancreatic cancer tumors that may help guide future therapeutic interventions for treatment.

18 Oct 2022

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies that can block metastasis.

18 Oct 2022

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upwards of a billion dollars.

18 Oct 2022

Recent innovations in infectious disease diagnostics

A recent Clinical Biochemistry editorial reports the latest innovations in the field of infectious disease diagnostics.

17 Oct 2022

KAUST study reveals unexpected role for zinc in the prevention of Parkinson's disease

Revealing zinc's interaction with a critical transport protein underscores the need to study biological pathways under physiologically relevant conditions.

17 Oct 2022

Novel drug target for triple-negative breast cancer discovered

Research led by Dr. Suresh Alahari, Professor of Biochemistry at LSU Health New Orleans' Schools of Medicine and Graduate Studies, reports a combination of a novel small inhibitory molecule and an FDA-approved chemotherapy drug suppresses the growth of triple-negative breast cancer cells synergistically.

17 Oct 2022

Increased TMPRSS2 expression in tongue tissue of females and alcohol drinkers identified as a potential risk factor for SARS-CoV-2 infection

Researchers explored the association between the expressions of the ACE-2 receptor and TMPRSS2 in the tongue tissue and dysgeusia during SARS-CoV-2 infections.

17 Oct 2022

How the ‘love hormone’ oxytocin may have heart-healing properties

In this interview, News Medical speaks to Dr. Aitor Aguirre, Assistant Professor of Biomedical Engineering at Michigan State University, about how the ‘love hormone’ oxytocin may provide heart-healing properties.

17 Oct 2022

A rare case of Hashimoto encephalopathy after COVID vaccination

In a recent ‘Letter to the Editor’ published in the English edition of the journal Neurologandiacute, researchers reported the rare occurrence of Hashimoto encephalopathy in a recipient of the (COVID-19) vaccine Spikevax. Spikevax, research name mRNA-1273, is a COVID-19 vaccine based on the messenger ribonucleic acid (mRNA) technology.

16 Oct 2022

Biochemistry News and Research

New discovery may change the textbook model of GPCR-mediated signaling

Discovery provides better understanding of retinal protein's structure and function

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

TANGO2 plays a role in heme homeostasis, research reveals

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Nutrition education needed for all healthcare professionals to better support public health, research suggests

Common oral bacterium promotes tumor progression-associated activity in pancreatic cancer cells

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

Recent innovations in infectious disease diagnostics

KAUST study reveals unexpected role for zinc in the prevention of Parkinson's disease

Novel drug target for triple-negative breast cancer discovered

Increased TMPRSS2 expression in tongue tissue of females and alcohol drinkers identified as a potential risk factor for SARS-CoV-2 infection

How the ‘love hormone’ oxytocin may have heart-healing properties

A rare case of Hashimoto encephalopathy after COVID vaccination

Protoporphyrin IX delayed fluorescence imaging as a modality for hypoxia-based oncologic surgical guidance

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Virginia Tech researchers examine how sleep deprivation may affect mosquito’s ability to spread disease

Researchers uncover an intriguing previously unknown ability of Swiss army knife enzyme

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