Cell Death News and Research

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Researchers uncover a new way the immune system detects coronavirus infection

In a recent study posted to bioRxiv*, researchers in the United States demonstrated that the main protease (Mpro) of coronaviruses (CoVs) activates host inflammasome responses.

27 Sep 2022

Study identifies potential therapeutic targets for preventing aminoglycoside-induced hearing loss

Researchers at Indiana University School of Medicine are developing new ways to study why an antibiotic causes hair cell death and permanent hearing loss in people.

27 Sep 2022

Does leptin play a role in Parkinson’s disease?

Scientists review in vitro and in vivo evidence associated with Parkinson's disease and leptin.

26 Sep 2022

Selectively targeting iGPX4 may be a promising therapeutic strategy for metabolic-associated fatty liver disease

This new article publication from Acta Pharmaceutica Sinica B, discusses targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease.

26 Sep 2022

Researchers successfully deliver a common blood pressure drug directly to cells’ ‘power plants’

In a study using lab-grown cells, Johns Hopkins Medicine researchers specializing in aging report they have successfully delivered a common blood pressure drug directly to the inner membrane of mitochondria, the "power plants" in the cells of humans, animals, plants and most other organisms.

20 Sep 2022

Research opens a new avenue for the treatment of cancer by phototherapy

One approach to treating cancer is photodynamic therapy using photo-uncaging systems, in which light is used to activate a cancer-fighting agent in situ at the tumor.

20 Sep 2022

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

Scientists have shown how tumour cells evade immunotherapy by generating unique, temporary cell-in-cell structures, where the inner cells remain in tact and can return to single tumour cells.

20 Sep 2022

Cell's anti-aging structures can set the damage threshold a cancer cell can sustain, study shows

A new study led by Claus M. Azzalin, group leader at Instituto de Medicina Molecular João Lobo Antunes- iMM and published today in the prestigious scientific journal Proceedings of the National Academy of Sciences (PNAS) shows, for the first time, that the cell's anti-aging structures – the telomeres – can set the damage threshold a cancer cell can sustain and above which cells cannot continue to divide and die.

20 Sep 2022

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process "autophagy."

19 Sep 2022

Large molecules glom together into dense droplets to create squishy circuits in cells

An emerging field explores how groups of molecules condense together inside cells, the way oil droplets assemble and separate from water in a vinaigrette.

14 Sep 2022

Experimental drug prolongs survival, improves muscle function in mice severe Duchenne muscular dystrophy

Researchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne muscular dystrophy (DMD).

13 Sep 2022

New long-term opioid use associated with a heightened risk of death, study finds

New long term use of opioids to quell pain after lung cancer surgery is linked to a 40% heightened risk of death from any cause within the next 2 years, finds research published online in the journal Regional Anesthesia & Pain Medicine.

13 Sep 2022

Exercise hormone reduces protein levels linked to Parkinson's disease

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice.

12 Sep 2022

Using Q-bodies for imaging intracellular proteins in live cells

Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development.

9 Sep 2022

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020.

9 Sep 2022

Research on the antimicrobial effects of human milk oligosaccharides

In a recent review published in the journal Current Opinion in Chemical Biology, researchers discussed the latest advances in the antimicrobial properties of human milk.

9 Sep 2022

Licorice compounds proposed as effective candidates for treatment of COVID-19

Researchers describe the different mechanisms by which licorice active ingredients target SARS-CoV-2.

8 Sep 2022

The role of some important antioxidants in major clinical outcomes of subjects with COVID-19

Researchers investigated the role of antioxidants such as selenium, zinc, α-lipoic acid, and vitamins A, E, D, and C in improving the clinical outcomes of COVID-19.

8 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences 5 Sep 2022

Depletion of reactive astrocytes regresses glioblastoma

A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth. The work found that both mechanisms are controlled by brain cells called astrocytes, and in their absence, the tumor cells die and are eliminated.

2 Sep 2022

Cell Death News and Research

Researchers uncover a new way the immune system detects coronavirus infection

Study identifies potential therapeutic targets for preventing aminoglycoside-induced hearing loss

Does leptin play a role in Parkinson’s disease?

Selectively targeting iGPX4 may be a promising therapeutic strategy for metabolic-associated fatty liver disease

Researchers successfully deliver a common blood pressure drug directly to cells’ ‘power plants’

Research opens a new avenue for the treatment of cancer by phototherapy

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

Cell's anti-aging structures can set the damage threshold a cancer cell can sustain, study shows

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

Large molecules glom together into dense droplets to create squishy circuits in cells

Experimental drug prolongs survival, improves muscle function in mice severe Duchenne muscular dystrophy

New long-term opioid use associated with a heightened risk of death, study finds

Exercise hormone reduces protein levels linked to Parkinson's disease

Using Q-bodies for imaging intracellular proteins in live cells

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

Research on the antimicrobial effects of human milk oligosaccharides

Licorice compounds proposed as effective candidates for treatment of COVID-19

The role of some important antioxidants in major clinical outcomes of subjects with COVID-19

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Depletion of reactive astrocytes regresses glioblastoma

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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