Neurodegenerative Diseases News and Research

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Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Researchers from the Neurobiology of miRNA team coordinated by Davide De Pietri Tonelli at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) has discovered the correlation between a class of small RNA molecules, piRNAs, and brain inflammation.

15 Dec 2022

Study uncovers previously unknown genetic cause of late-onset cerebellar ataxia

A new study published on Dec. 14, 2022 in the New England Journal of Medicine reports the identification of a previously unknown genetic cause of a late-onset cerebellar ataxia, a discovery that will improve diagnosis and open new treatment avenues for this progressive condition.

15 Dec 2022

Study reveals limited effects of longevity treatments on the aging process

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

14 Dec 2022

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Amyloid plaques — protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, early-onset Alzheimer's, according to research funded by the National Institutes of Health.

12 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Researchers discover a previously unknown mechanism that drives aging

Northwestern University researchers have discovered a previously unknown mechanism that drives aging.

9 Dec 2022

New study details the neuronal response to excessive aged-related iron accumulation

Iron (Fe) accumulates in the brain cortex with aging. A plethora of studies indicate that progressive iron accumulation in the substantia nigra (SN) in the aged human brain is a major risk factor for Parkinson's disease (PD) and other neurodegenerative diseases, but not everyone.

6 Dec 2022

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

University of Central Florida researchers have created unique technology for treating osteoporosis that uses nanobubbles to deliver treatment to targeted areas of a person's body.

6 Dec 2022

Scientists discover new potential mechanism for vision loss

Visual cells in the human retina may not simply die in some diseases, but are mechanically transported out of the retina beforehand.

1 Dec 2022

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

A change in the DNA code (mutation) of a gene that plays a key role in the brain's immune defenses may prevent related cells from clearing away protein-filled clumps, a new study in mice shows.

30 Nov 2022

Study reveals wasteosomes as markers of chronic glymphatic system insufficiency

A new study led by researchers from the University of Barcelona shows that wasteosomes - structures that act as containers for brain waste products - indicate a malfunction of the glymphatic system, a recently discovered system that is an important brain-cleaning mechanism.

30 Nov 2022

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

30 Nov 2022

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

30 Nov 2022

Mediterranean diet provides many benefits to overweight and obese seniors

The World Health Organization (WHO) defines overweight and obesity as excessive fat accumulations, posing health risks. A Spanish survey indicated a significant increase in obesity (from 7.4 % to 17.4%.) between 1987 and 2017. Interestingly, it was observed that obesity is more prevalent in men than in women who are below 65 years of age. However, beyond the age of 65, obesity in women outnumbered men.

29 Nov 2022

Neurodegenerative Diseases News and Research

Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Study uncovers previously unknown genetic cause of late-onset cerebellar ataxia

Study reveals limited effects of longevity treatments on the aging process

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

How human cell atlases provide the missing links between genes, diseases and therapies

Researchers discover a previously unknown mechanism that drives aging

New study details the neuronal response to excessive aged-related iron accumulation

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

Scientists discover new potential mechanism for vision loss

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

Study reveals wasteosomes as markers of chronic glymphatic system insufficiency

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

Mediterranean diet provides many benefits to overweight and obese seniors

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Study provides a key link between the social environment and healthy brains

Study reveals structural insights into the elusive tankyrase protein that fuels bowel cancer

Time-restricted eating may benefit Alzheimer's

Gut microbiome plays a role in Alzheimer's

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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