Peptides News and Research

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Developing a COVID-19 vaccine using inactivated E. coli

A team of researchers inactivated whole-cell E.coli with a reduced genome and utilized this to express coronavirus-specific fusion peptides, demonstrating a potent anamnestic response.

19 Mar 2021

Using nanoparticles for efficient delivery of antimicrobial peptides to treat deep infections

Announcing a new article publication for BIO Integration journal. In this review article the authors Yingxue Deng, Rui Huang, Songyin Huang and Menghua Xiong from South China University of Technology, Guangzhou, Guangdong, P. R. China and Sun Yat-sen University, Guangzhou, Guangdong, P. R. China discuss how nanoparticles enable efficient delivery of antimicrobial peptides for the treatment of deep infections.

18 Mar 2021

SARS-CoV-2 Brazilian variant may potentially escape T cell-mediated host immune responses

A team of scientists from Brazil recently explored the abilities of the UK, South African, and Brazilian variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to evade host CD8+ T cell responses induced by natural infection or vaccination. The findings reveal reduced antigenic coverage for the P.2 Brazilian lineage, indicating its ability to evade SARS-CoV-2-induced T cell responses.

16 Mar 2021

48Hour Discovery and Merck join hands to accelerate drug development

48Hour Discovery and CQDM are proud to announced that the company has been awarded $800,000 for peptide drug discovery using its patented drug discovery platform.

15 Mar 2021

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

In a recent bioRxiv preprint research paper, Botond Z. Igyártó and colleagues from Thomas Jefferson University demonstrated the inflammatory nature of the lipid nanoparticles (LNPs).

15 Mar 2021

Scientists increase potency of HIV-1 antibody, identify new ways to develop vaccines

Much like coronavirus, circulating HIV-1 viruses mutate into diverse variants that pose challenges for scientists developing vaccines to protect people from HIV/AIDS.

12 Mar 2021

New approach could treat infertility caused by abnormal GnRH secretion

Reports suggest that at least 25% of ovarian disorders are due to dysfunction of the brain mechanism in the hypothalamus that controls the gonadotropin-releasing hormone (GnRH), which is a molecule that governs the reproductive function in men and women by regulating the release of a range of reproductive hormones into the body, particularly gonadotropins, from the pituitary gland, which is located underneath the brain.

12 Mar 2021

New biodegradable nanoprobes could help detect cancer more accurately

New Imperial-developed nanoprobes tested in zebrafish could help detect cancer more accurately and might aid diagnosis and therapy in the future.

11 Mar 2021

Is a single mRNA COVID-19 vaccine dose enough for recovered individuals?

A new study deals with the evaluation of adaptive immune response to COVID-19 vaccination in candidates who have recovered from SARS-CoV-2 infection.

11 Mar 2021

Information from ancient teeth could reveal new insights about the past

There's a surprising amount of information stored in the hardened plaque, or calculus, between teeth. And if that calculus belongs to the remains of a person who lived in ancient times, the information could reveal new insights about the past.

11 Mar 2021

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.

10 Mar 2021

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

9 Mar 2021

SARS-CoV-2's amyloid-driving nucleoprotein could inform future therapeutic research

New research led by researchers at the University of California Los Angeles and the University of Texas Southwestern Medical Center in the US suggests that functional amyloid fibrils could play an integral role in developing COVID-19 treatments.

9 Mar 2021

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

A new study, released as a preprint on the bioRxiv* server, reports an optimized coronavirus disease 2019 (COVID-19) vaccine candidate, which, claim the researchers, may be less likely to produce reactions like fevers. It may also have increased protective potential against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

9 Mar 2021

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

At the virtual 17th US HUPO Conference (US HUPO 2021), Bruker Corporation (Nasdaq: BRKR) today announces progress with several collaborations in deep, unbiased plasma proteomics, leveraging the speed, sensitivity and dynamic range of 4D proteomics on timsTOF Pro systems.

From Bruker Daltonics 9 Mar 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

The currently developed vaccines against SARS-CoV-2 include the RBD in their immunogen. With a similar objective, a new study developed an RBD protein-based vaccine candidate against the SARS-CoV-2, using self-assembling Helicobacter pylori-bullfrog ferritin nanoparticles as an antigen delivery system. The study is published recently in the journal mBio (by the American Society of Microbiology).

8 Mar 2021

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

4 Mar 2021

The Role of D-Amino Acids in Humans

In this interview, Dr. Daniel Armstrong from the University of Texas at Arlington talks to News-Medical Life Sciences about his upcoming Pittcon presentation.

From Pittcon 4 Mar 2021

New Nature Communications publication by Mann & Theis Groups harnesses the benefits of large-scale peptide collisional cross section (CCS) measurements and deep learning for 4D-proteomics

Bruker Corporation today announces a seminal publication from the groups of Professors Matthias Mann and Fabian Theis in the journal Nature Communications with the title ‘Deep learning the collisional cross sections of the peptide universe from a million experimental values’ by Florian Meier et al.

From Bruker Daltonics 4 Mar 2021

SARS-CoV-2 variants do not substantially affect CD4+ and CD8+ T cell responses, study shows

Researchers from California in the United States have conducted a study showing that important adaptive immune responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are not affected by four recently emerged variants of the virus.

3 Mar 2021

Peptides News and Research

Developing a COVID-19 vaccine using inactivated E. coli

Using nanoparticles for efficient delivery of antimicrobial peptides to treat deep infections

SARS-CoV-2 Brazilian variant may potentially escape T cell-mediated host immune responses

48Hour Discovery and Merck join hands to accelerate drug development

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

Scientists increase potency of HIV-1 antibody, identify new ways to develop vaccines

New approach could treat infertility caused by abnormal GnRH secretion

New biodegradable nanoprobes could help detect cancer more accurately

Is a single mRNA COVID-19 vaccine dose enough for recovered individuals?

Information from ancient teeth could reveal new insights about the past

Researchers confirm new drug development route for treating multiple sclerosis, asthma

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

SARS-CoV-2's amyloid-driving nucleoprotein could inform future therapeutic research

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

The Role of D-Amino Acids in Humans

New Nature Communications publication by Mann & Theis Groups harnesses the benefits of large-scale peptide collisional cross section (CCS) measurements and deep learning for 4D-proteomics

SARS-CoV-2 variants do not substantially affect CD4+ and CD8+ T cell responses, study shows

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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