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Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.

27 Sep 2023

Improving treatment outcomes for individuals with acute spinal cord injury

A special focus issue of the peer-reviewed Journal of Neurotrauma highlights the latest findings of the North American Clinical Trials Network (NACTN), aimed at improving outcomes for individuals with acute spinal cord injury (SCI).

27 Sep 2023

Prolonged mismatch between calories eaten and burned may be putting many athletes at risk of REDs

The estimated prevalence of REDs varies by sport, ranging from 15% to 80%. The syndrome often goes unrecognised by athletes themselves, their coaches, and team clinicians, and may unwittingly be exacerbated by the 'sports culture,' because of the perceived short term gains on performance from intentionally or unintentionally limiting calorie intake, warns the Statement.

26 Sep 2023

Could next-generation antimicrobial agents act as an alternative to standard antibiotics?

Next-generation antimicrobial agents (NGAs) as a potential alternative to standard antibiotics

26 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions.

25 Sep 2023

Study discovers a new endocytic pathway in budding yeast

Endocytosis is an important cellular process through which cells internalize substances such as water and nutrients.

25 Sep 2023

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Researchers proposed a simplified approach for analyzing mRNA vaccines using long-read sequencing.

22 Sep 2023

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

An international clinical trial exploring a new way to treat rare and aggressive gynaecological cancers has launched in Melbourne.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Digital vision training may not be an effective treatment for amblyopia in children

In the "ThemenCheck Medizin" procedure offered by the German Institute for Quality and Efficiency in Health Care (IQWiG), interested members of the public can submit proposals for the assessment of medical procedures and technologies.

21 Sep 2023

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

In a collaborative study published in The Lancet Microbe, the team of scientists, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and WEHI (Walter and Eliza Hall Institute of Medical Research), revealed MPXV-CRISPR – a powerful diagnostic tool capable of detecting MPXV in clinical samples with acute precision and at a faster rate than any other method, thanks to the power of CRISPR technology.

20 Sep 2023

CST and Leica Biosystems partner to enable companion diagnostics for personalized medicine

Cell Signaling Technology (CST), a life science discovery technology company and leading provider of antibodies, kits, and services, is partnered with Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging, to support the development of companion diagnostics (CDx) assays using the extensive portfolio of best-in-class antibodies from CST validated for immunohistochemistry (IHC).

From Cell Signaling Technology 20 Sep 2023

Hospital wastewater teeming with antibiotic-resistant genes, poses infection risk

Researchers from the UK and the Republic of Ireland have found high levels of antibiotic-resistant genes in the wastewater system of a major teaching hospital. The findings underscore the urgent need for regular decontamination and more stringent infection control measures to protect patients.

19 Sep 2023

UK Markey Cancer Center becomes NCI-Designated Comprehensive Cancer Center

The University of Kentucky Markey Cancer Center announced today that it has earned a National Cancer Institute "Comprehensive" Cancer Center designation, the highest level of recognition awarded by the NCI. Markey is the first and only center in Kentucky to achieve this designation, and the next-closest Comprehensive Cancer Center is nearly 200 miles from Lexington.

15 Sep 2023

New nano-thin superbug-slaying material could revolutionize wound healing

Researchers have invented a nano-thin superbug-slaying material that could one day be integrated into wound dressings and implants to prevent or heal bacterial infections.

14 Sep 2023

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Researchers designed and evaluated a multi-epitope vaccine targeting the main outer membrane protein of Chlamydia pneumoniae using immunoinformatics.

14 Sep 2023

UC Riverside study uncovers COVID's Achilles heel

New UC Riverside research has revealed COVID's Achilles heel - its dependence on key human proteins for its replication - which can be used to prevent the virus from making people sick.

13 Sep 2023

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

Researchers identify a super-enhancer-regulated RNA-binding protein cascade that drives the growth of pancreatic ductal adenocarcinoma, a deadly form of pancreatic cancer. The discovery offers a promising new avenue for targeted therapy, potentially sidestepping severe side effects associated with other treatments.

10 Sep 2023

Translation News and Research

Study details the key role played by neutrophils in ensuring survival of brain cancers

Improving treatment outcomes for individuals with acute spinal cord injury

Prolonged mismatch between calories eaten and burned may be putting many athletes at risk of REDs

Could next-generation antimicrobial agents act as an alternative to standard antibiotics?

Intranasal vaccine shows promise against COVID variants in hamsters

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Study discovers a new endocytic pathway in budding yeast

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Digital vision training may not be an effective treatment for amblyopia in children

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

CST and Leica Biosystems partner to enable companion diagnostics for personalized medicine

Hospital wastewater teeming with antibiotic-resistant genes, poses infection risk

UK Markey Cancer Center becomes NCI-Designated Comprehensive Cancer Center

New nano-thin superbug-slaying material could revolutionize wound healing

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

UC Riverside study uncovers COVID's Achilles heel

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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