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Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Osaka Researchers, in partnership with other Japanese and U.S. scientists, report a new gene target, KPNB1, for treatment against epithelial ovarian cancer (EOC).

28 Sep 2017

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Cancers driven by mutations in the KRAS gene are among the most deadly. For decades, researchers have tried unsuccessfully to directly target mutant KRAS proteins as a means to treat tumors.

28 Sep 2017

Rogue messengers can negatively affect the body's immune system response against cancer

Researchers from Trinity College Dublin have made a discovery around treatment-resistant breast cancer that may turn the phrase, 'don't shoot the messenger', on its head. The scientists have found that cell to cell messengers released by cancer cells which are not responding to treatment, can negatively affect the body's immune system response against cancer.

28 Sep 2017

Blood test may predict treatment outcomes for patients with localized NSCLC

A new study demonstrates that a blood test to detect cancer may predict treatment outcomes for patients with localized non-small cell lung cancer (NSCLC) and afford physicians additional lead time to personalize treatment for recurrent disease.

28 Sep 2017

Cancer vaccines need to target immune fighters that can withstand battle against malicious tumors

Cancer vaccines may need to better target T cells that can hold up to the long fight against cancer, scientists report.

27 Sep 2017

Clinical trial demonstrates safety, efficacy of focused ultrasound to treat pediatric osteoid osteoma

Karun Sharma, MD, PhD, Director of Interventional Radiology, and colleagues at Sheikh Zayed Institute for Pediatric Surgical Innovation at Children's National Health System in Washington, DC, have completed their clinical trial to treat benign but painful bone tumors (osteoid osteoma) in children.

27 Sep 2017

Plant substance shows inhibitory effects on cancer stem cells

The plant Ambrosia arborescens grows at a high elevation in large parts of South America, and is traditionally used as a medicinal plant. The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three different breast cancer cell lines.

27 Sep 2017

Researchers explore potential of traditional Chinese ink for cancer treatment

For hundreds of years, Chinese calligraphers have used a plant-based ink to create beautiful messages and art. Now, one group reports in ACS Omega that this ink could noninvasively and effectively treat cancer cells that spread, or metastasize, to lymph nodes.

27 Sep 2017

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

Notre Dame's HCRI publishes two papers involving ovarian cancer research

Two papers involving ovarian cancer research at the University of Notre Dame's Harper Cancer Research Institute, one featuring new research and the other a review article, were published as cover stories in their respective journals.

27 Sep 2017

Huddersfield cancer scientists aim to develop new treatments for young people

CANCER researchers at the University of Huddersfield aim to develop new treatments specifically for young people and they will be aided in their quest by financial support from a locally-based charity.

27 Sep 2017

Drug combination produces synergistic effect against growth of triple-negative breast cancer

In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death.

26 Sep 2017

New approaches to treat aggressive NUT midline carcinoma

Precision medicine, which custom-tailors therapies to the needs of individual patients, is becoming more and more important in cancer therapy. Today, molecular-biological diagnostics can precisely identify alterations in tumor cells.

26 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Pediatric researchers investigating the childhood cancer neuroblastoma have identified common gene variants that raise the risk of an aggressive form of that disease. The discovery may assist doctors in better diagnosing subtypes of neuroblastoma.

25 Sep 2017

Probiotic bacteria can change intestinal flora of patients with colon cancer, study finds

Living lactic acid bacteria, probiotics, can change the intestinal flora of patients with cancer of the colon. These are the findings of a study published in the journal BMJ Open Gastroenterology.

25 Sep 2017

New MRI contrast agent differentiates between aggressive and slow-growing breast cancers

A new magnetic resonance imaging (MRI) contrast agent being tested by researchers at Case Western Reserve University not only pinpoints breast cancers at early stages but differentiates between aggressive and slow-growing types.

25 Sep 2017

New gel patch could speed up healing and minimize formation of scars

Scientists from Nanyang Technological University, Singapore have developed a new gel patch prototype that could speed up the healing of a skin wound while minimizing the formation of scars. The team unveiled the patch today as a proof-of-concept.

25 Sep 2017

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Research by Rutgers Cancer Institute of New Jersey investigators shows the targeting of a binding protein of mutant p53 known as Rac1 could lead to new therapeutic strategies for patients whose cancer carries mutations in the p53 gene.

22 Sep 2017

NCI selects UTSW cancer researcher to receive Outstanding Investigator Award

The National Cancer Institute has selected UT Southwestern Medical Center cancer researcher Dr. Ralph DeBerardinis to receive its prestigious Outstanding Investigator Award.

22 Sep 2017

Tumor News and Research

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Rogue messengers can negatively affect the body's immune system response against cancer

Blood test may predict treatment outcomes for patients with localized NSCLC

Cancer vaccines need to target immune fighters that can withstand battle against malicious tumors

Clinical trial demonstrates safety, efficacy of focused ultrasound to treat pediatric osteoid osteoma

Plant substance shows inhibitory effects on cancer stem cells

Researchers explore potential of traditional Chinese ink for cancer treatment

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Notre Dame's HCRI publishes two papers involving ovarian cancer research

Huddersfield cancer scientists aim to develop new treatments for young people

Drug combination produces synergistic effect against growth of triple-negative breast cancer

New approaches to treat aggressive NUT midline carcinoma

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Probiotic bacteria can change intestinal flora of patients with colon cancer, study finds

New MRI contrast agent differentiates between aggressive and slow-growing breast cancers

New gel patch could speed up healing and minimize formation of scars

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

NCI selects UTSW cancer researcher to receive Outstanding Investigator Award

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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