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Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

Researchers explored genomic rearrangements in monkeypox virus genomes and investigated whether such rearrangements represented viral adaption to humans (host).

25 Oct 2022

Scientists develop new method to study the proteins released by cells

A new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer, has been developed by scientists at the Francis Crick Institute and Imperial College London.

25 Oct 2022

Harmless group of bacteria linked with increased risk of death in patients with end-stage renal disease

A big group of bacteria found in our soil, our water and our showerheads are harmless for most of us, but a new study indicates they are associated with an increased risk of dying in individuals whose kidneys have failed.

25 Oct 2022

Researchers design a COVID-19 vaccine construct using hybrid SARS-CoV-2 spike protein and nucleocapsid protein peptides

Researchers designed a COVID-19 vaccine construct using hybrid SARS-CoV-2 S protein (containing SARS-CoV-2 Delta and Omicron variant mutations) and N protein peptides that confer T lymphocyte-mediated immune protection.

25 Oct 2022

The impact of existing and theoretical mutations on SARS-CoV-2 CD8+ T cell targets

Researchers evaluated the effect of mutations in SARS-CoV-2 variants of concern on CD8+ T cell responses.

25 Oct 2022

Researchers streamline way to manufacture CAR T-cells in just 24 hours

Researchers at University Hospitals (UH) Seidman Cancer Center and a biotech start-up company have developed a streamlined way to manufacture CAR T-cells for immunotherapy treatment in just 24 hours – an improvement over the team's previous benchmark of eight days and commercial suppliers that typically take three weeks.

25 Oct 2022

Researchers discover molecular mechanisms behind mitochondrial dysfunction in chronic heart failure

Investigations in Japan have uncovered some molecular mechanisms behind mitochondrial dysfunction in chronic heart failure.

25 Oct 2022

MSU researchers receive $3 million NIH grant to study testosterone’s role in depression

Major depressive disorder affects women twice as often as men, but researchers are still trying to identify the reasons why.

24 Oct 2022

In utero exposure to flame retardant results in altered brain development in newborn rats

A new study from North Carolina State University shows that exposure in utero to the flame retardant FireMaster 550 (FM 550), or to its individual brominated (BFR) or organophosphate ester (OPFR) components, resulted in altered brain development in newborn rats.

24 Oct 2022

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

Using a novel systems biology approach, scientists at University of California San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis (RA), a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.

24 Oct 2022

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Alzheimer's disease (AD), characterized by an accumulation of β-amyloid protein (Aβ) in brain tissue, is a leading cause of dementia.

24 Oct 2022

Researchers discover new type of microglia related to stroke in the ischemia/reperfusion injured brain

A research team, affiliated with UNIST has identified a new type of microglia associated with stroke in the ischemia/reperfusion (I/R) injured brain.

24 Oct 2022

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

Celebrating the Alderley Park Grand Opening

HQ Plasmid Center of Excellence based at UK life science hotspot now open for business.

From Charles Rivers Laboratories Cell and Gene Therapy 24 Oct 2022

What is the efficacy of mulberry component Kuwanon C against COVID-19?

A recent study determined the underlying antiviral mechanism of KC associated with the inhibition of SARS-CoV-2.

24 Oct 2022

Longitudinal cohort study of primary healthcare workers reveals long-lasting SARS-CoV-2 humoral immunity in the absence of vaccination

Researchers performed a longitudinal cohort study to assess the levels of immunoglobulins M (IgM), G (IgG), and A (IgA) against the spike and nucleocapsid proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Oct 2022

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Researchers developed integrated host-microbe plasma metagenomics to facilitate sepsis diagnosis.

24 Oct 2022

B Cell News and Research

Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

Scientists develop new method to study the proteins released by cells

Harmless group of bacteria linked with increased risk of death in patients with end-stage renal disease

Researchers design a COVID-19 vaccine construct using hybrid SARS-CoV-2 spike protein and nucleocapsid protein peptides

The impact of existing and theoretical mutations on SARS-CoV-2 CD8+ T cell targets

Researchers streamline way to manufacture CAR T-cells in just 24 hours

Researchers discover molecular mechanisms behind mitochondrial dysfunction in chronic heart failure

MSU researchers receive $3 million NIH grant to study testosterone’s role in depression

In utero exposure to flame retardant results in altered brain development in newborn rats

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Researchers discover new type of microglia related to stroke in the ischemia/reperfusion injured brain

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

Celebrating the Alderley Park Grand Opening

What is the efficacy of mulberry component Kuwanon C against COVID-19?

Longitudinal cohort study of primary healthcare workers reveals long-lasting SARS-CoV-2 humoral immunity in the absence of vaccination

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Effectiveness of COVID-19 vaccines in preventing hospitalizations among immunocompromised adults

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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