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UniSA researchers are putting cancer patients at the heart of clinical trials

From bench to bedside, the journey towards new cancer therapies is full of challenges. Clinical trials – where new treatments are tested on people – are vital, but with fewer than five per cent of cancer patients participating worldwide, it’s a long road to travel.

1 Sep 2021

Pet dogs can detect specific smell associated with epileptic seizures

New research led by Queen’s University Belfast has shown that dogs can predict epileptic seizures, offering a warning sign to owners that has the potential to save lives.

1 Sep 2021

Researchers develop new photodynamic therapy for the treatment of deep tumors

Therapies should be highly effective and as free as possible of side effects—a big challenge, particularly in the case of cancer.

1 Sep 2021

Manualized equine-assisted therapy shows promise for treating veterans with PTSD

As veterans have high rates of posttraumatic stress disorder (PTSD) and historically poor treatment outcomes and high attrition, alternative treatments have gained much popularity despite lack of rigorous research.

1 Sep 2021

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

After over a century of development, cancer immunotherapy (CIT) has risen to become a promising approach for treating cancer. Unlike conventional methods that try to kill cancer cells directly, CIT involves modifying or stimulating the immune system's natural ability to fight the disease. So far, various CIT treatments have shown remarkable results in terms of survival rates, and many new and combination strategies are currently under study.

1 Sep 2021

Walking can power an implantable stimulator device to speed up tendon healing

Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, have shown how the simple act of walking can power an implantable stimulator device to speed up treatment of musculoskeletal diseases.

31 Aug 2021

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy.

31 Aug 2021

New study could help orthopedic surgeons to better identify patients for foot surgery

A new study by researchers at Hospital for Special Surgery in New York City could help orthopedic surgeons better identify which patients will benefit most from surgery to correct debilitating age-related deterioration of their foot arches.

31 Aug 2021

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

A new study published in mBio discusses the microevolution of SARS-CoV-2.

31 Aug 2021

Community-based program can help reduce in-home falls among older adults

For many aging Americans, the dream of maintaining an active, independent lifestyle while living at home comes crashing down with a fall. Falls are the leading cause of injury, accidental death and premature placement in a nursing home among older adults in the United States.

31 Aug 2021

Hormones play a vital role in the development of breast cancer

A study by RCSI University of Medicine and Health Sciences has provided greater insight into the role that hormones play in the development of breast cancer in patients. The novel findings could enhance the treatment for breast cancer, assisting clinicians in optimising individual patient care and improving overall survival rates for patients.

31 Aug 2021

New compounds offer a two-for-one punch to fight estrogen-sensitive breast cancer

A set of compounds developed by scientists at Scripps Research in Florida target estrogen-sensitive breast cancer cells in new ways, potentially creating better options for patients with treatment-resistant cancers.

31 Aug 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

Study identifies actionable genes and candidate drugs in biliary tract cancer using a knowledgebase

Oncotarget published "Actionability evaluation of biliary tract cancer by genome transcriptome analysis and Asian cancer knowledgebase" which reported that it is necessary to investigate actionable genes and candidate drugs using a sophisticated knowledgebase and characterize BTCs immunologically for evaluating the actionability of molecular and immune therapies.

31 Aug 2021

AI approach helps identify heart failure patients who will benefit from beta-blocker therapy

Researchers at the University of Birmingham have developed a new way to identify patients with heart failure who will benefit from treatment with beta-blockers.

31 Aug 2021

Research sheds light on potential biological mechanisms that impact adherence to medications

How strictly patients follow a prescribed drug treatment (drug adherence) is clearly important if the therapy is to have maximum effect. A number of things can affect adherence, including behavioral and socioeconomic factors, but to date there have been few investigations into the role played by genetics. Now, research to be presented at the annual conference of the European Society of Human Genetics today has thrown new light on the potential biological mechanisms that can affect adherence to treatment.

31 Aug 2021

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Aging-US published "The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence" which reported that cellular senescence may be a side effect of chemotherapy and other anti-cancer treatments that may promote inflammation and paracrine secondary senescence in healthy tissues.

31 Aug 2021

Cardiovascular safety of prostate cancer treatments remains unresolved

The relative cardiovascular safety of different types of androgen deprivation therapy (ADT) for prostate cancer remains unresolved after the PRONOUNCE trial was terminated early. The late breaking research is presented in a Hot Line session today at ESC Congress 2021.

30 Aug 2021

Intensive blood-pressure control benefits older hypertensive patients

Aggressive blood pressure treatment in older hypertensive patients lowers the incidence of cardiovascular events compared to standard therapy, without increasing adverse outcomes. That's the finding of late breaking research presented in a Hot Line session today at ESC Congress 2021.

30 Aug 2021

Combination therapy given in fixed doses can cut risk of cardiovascular disease by more than half

A combination therapy of aspirin, statins and at least two blood pressure medications given in fixed doses can slash the risk of fatal cardiovascular disease (CVD) by more than half, says an international study led by Hamilton researchers.

30 Aug 2021

Therapy News and Research

UniSA researchers are putting cancer patients at the heart of clinical trials

Pet dogs can detect specific smell associated with epileptic seizures

Researchers develop new photodynamic therapy for the treatment of deep tumors

Manualized equine-assisted therapy shows promise for treating veterans with PTSD

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

Walking can power an implantable stimulator device to speed up tendon healing

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

New study could help orthopedic surgeons to better identify patients for foot surgery

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

Community-based program can help reduce in-home falls among older adults

Hormones play a vital role in the development of breast cancer

New compounds offer a two-for-one punch to fight estrogen-sensitive breast cancer

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Study identifies actionable genes and candidate drugs in biliary tract cancer using a knowledgebase

AI approach helps identify heart failure patients who will benefit from beta-blocker therapy

Research sheds light on potential biological mechanisms that impact adherence to medications

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Cardiovascular safety of prostate cancer treatments remains unresolved

Intensive blood-pressure control benefits older hypertensive patients

Combination therapy given in fixed doses can cut risk of cardiovascular disease by more than half

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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