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Tools of Undiagnosed Diseases Network help unravel mystery of rare genetic disease

The first patient was a mystery. Arriving at Duke six years ago at the age of three, the youngster had mild developmental delays and physical characteristics that included a large body and large head circumference.

29 Sep 2016

New 3-D printed biomaterial could be effective in treating children with bone defects

A Northwestern University research team has developed a 3-D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic "bone" material, whose shape can be easily customized, one day could be especially useful for the treatment of bone defects in children.

29 Sep 2016

Researchers uncover key factor for promoting wound healing after corneal injuries

In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs) — which can differentiate into a variety of cells, including bone, cartilage, muscle and fat cells — are capable of returning clarity to scarred corneas; however, the mechanisms by which this happens remained a mystery — until now.

29 Sep 2016

Living healthy lifestyle could benefit men with high genetic risk of developing bowel cancer

Men with a high genetic risk of developing bowel cancer over the next 25 years could have a lower risk of developing the disease if they also have a healthy lifestyle, according to a Cancer Research UK-funded study published in the journal Genetics in Medicine today (Thursday).

29 Sep 2016

Trafficked people in England face significant barriers to access healthcare services, study finds

Trafficked people in England are often denied healthcare and face significant barriers to access NHS services, reveals new independent research funded by Department of Health Policy Research Programme and carried out by a team led by King's College London, the University of Stirling, The London School of Hygiene and Tropical Medicine and The University of Central Lancashire.

29 Sep 2016

Study reveals many female high school athletes do not report concussion injuries to trainers

Nearly half of female athletes participating in high school sports have had a diagnosed or suspected concussion—but most don't report these sports-related injuries to coaches or trainers, reports a study in the Journal of Trauma Nursing, official publication of the Society of Trauma Nurses, published by Wolters Kluwer.

29 Sep 2016

Researchers find children with Tourette syndrome faster at assembling sounds than normal kids

Children with Tourette syndrome may process aspects of language faster than other children, a new study shows.

29 Sep 2016

HPV vaccine can decrease incidence of cervical pre-cancers among young women, research shows

Every 20 minutes, someone in the United States receives a cancer diagnosis related to human papillomavirus. HPV causes cancer of the cervix, anus and throat.

29 Sep 2016

Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

A Mayo Clinic research team has found evidence suggesting that the controversial practice of ovary removal in premenopausal women to prevent ovarian cancer should be discontinued in women who are not at high risk of cancer.

29 Sep 2016

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

The Alzheimer's Drug Discovery Foundation announces a $2.1 million grant awarded to R. Scott Turner, MD, PhD, of Georgetown University Medical Center to conduct a phase II clinical trial of low-dose nilotinib (marketed as Tasigna for use as a cancer therapy) in patients with Alzheimer's disease.

29 Sep 2016

Ki67 may help spare some breast cancer patients from sentinel lymph node biopsies

Breast cancer patients over 50 years old could be spared invasive procedures by use of stratification based on tumour size and molecular characteristics, including Ki67.

29 Sep 2016

Cell migration occurs by intermittent bursts of activity, researchers find

Cell migration is a central process in the development and maintenance of multicellular organisms.

29 Sep 2016

FDA approves automated insulin delivery device for type 1 diabetes

The Food and Drug Administration (FDA) has approved a device that automatically monitors blood glucose levels and delivers insulin when appropriate, for people aged 14 years and older who have type 1 diabetes.

29 Sep 2016

Does exercise eliminate the ill effects of sitting? An interview with Prof. Ulf Ekelund

In short, the detrimental effects of sitting for prolonged hours can be divided into acute, or short-term, and long-term effects.

29 Sep 2016

Study finds no link between milk intake and cardiovascular risk

Researchers in Valencia participated in an international study that has debunked the association between milk and dairy products and increased cardiovascular risk.

29 Sep 2016

Bioactive compound from neem plant shows promising effects on prostate cancer

A team of international researchers led by Associate Professor Gautam Sethi from the Department of Pharmacology at the Yong Loo Lin School of Medicine at the National University of Singapore has found that nimbolide, a bioactive terpenoid compound derived from Azadirachta indica or more commonly known as the neem plant, could reduce the size of prostate tumour by up to 70 per cent and suppress its spread or metastasis by half.

29 Sep 2016

Recycling existing drugs may help fight several types of cancer

Researchers at the University of Bergen have discovered that a drug against kidney cancer possibly can fight several types of cancer.

29 Sep 2016

Hypertension linked to cognitive issues in children and adolescents

Hypertension, more commonly known as high blood pressure, has increased significantly in children, paralleling the current childhood obesity epidemic.

29 Sep 2016

Researchers discover how signals from infectious bacteria get to inflammasome sensors

Researchers at St. Jude Children's Research Hospital have discovered the way signals from infectious bacteria gain entry into the cytoplasm of host cells to activate disease-fighting inflammasomes.

29 Sep 2016

Frequent nighttime hot flashes may trigger mild depression symptoms during menopause

A woman's perception that she is experiencing a high number of nighttime hot flashes can trigger mild symptoms of depression during menopause, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

28 Sep 2016

Research News and Research

Tools of Undiagnosed Diseases Network help unravel mystery of rare genetic disease

New 3-D printed biomaterial could be effective in treating children with bone defects

Researchers uncover key factor for promoting wound healing after corneal injuries

Living healthy lifestyle could benefit men with high genetic risk of developing bowel cancer

Trafficked people in England face significant barriers to access healthcare services, study finds

Study reveals many female high school athletes do not report concussion injuries to trainers

Researchers find children with Tourette syndrome faster at assembling sounds than normal kids

HPV vaccine can decrease incidence of cervical pre-cancers among young women, research shows

Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

Ki67 may help spare some breast cancer patients from sentinel lymph node biopsies

Cell migration occurs by intermittent bursts of activity, researchers find

FDA approves automated insulin delivery device for type 1 diabetes

Does exercise eliminate the ill effects of sitting? An interview with Prof. Ulf Ekelund

Study finds no link between milk intake and cardiovascular risk

Bioactive compound from neem plant shows promising effects on prostate cancer

Recycling existing drugs may help fight several types of cancer

Hypertension linked to cognitive issues in children and adolescents

Researchers discover how signals from infectious bacteria get to inflammasome sensors

Frequent nighttime hot flashes may trigger mild depression symptoms during menopause

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