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Study shows the importance of both obesity and biological sex in COVID-19 outcomes

A new animal study from Katherine Lee, a researcher with the West Virginia University School of Medicine, investigates why individuals with obesity may have a particularly difficult time fending off SARS-CoV-2, the virus that causes COVID-19.

19 Oct 2022

AI app to read COVID-19 lateral flow tests helps to reduce false results

An artificial intelligence app to read COVID-19 lateral flow tests helped to reduce false results in a new trial out today.

19 Oct 2022

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.

19 Oct 2022

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).

19 Oct 2022

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

A recent study under review at the journal Scientific Reports and currently available on the Research Square* preprint server reported the development of a robust pipeline for fabricating an mRNA vaccine portfolio to combat current and future coronavirus outbreaks, other infectious diseases, and cancer.

19 Oct 2022

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

A pseudovirus system based on deep mutational scanning determines how SARS-CoV-2 mutations can affect its ability to escape neutralization.

18 Oct 2022

SARS-CoV-2 placentitis may cause placental destruction and stillbirth in women not vaccinated for COVID-19

As compared to healthy women, pregnant women infected with SARS-CoV-2 are at a high risk of fatal clinical outcomes.

18 Oct 2022

New research finds microclotting and inflammatory molecule abnormalities in long-COVID

A new study published on the preprint server medRxiv* determines how endothelial activation and inflammation contribute to the formation of microclots in PASC.

18 Oct 2022

Penn State researchers lay the foundation for precision fabrication of tumor models

Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.

18 Oct 2022

Physical exercise improves cardiorespiratory fitness, alleviates adverse effects of cancer treatment

During chemotherapy, physical exercise intervention is safe, improves long-term cardiorespiratory fitness, and alleviates some of the adverse effects of cancer treatment, according to a study published in JACC: CardioOncology.

18 Oct 2022

Common oral bacterium promotes tumor progression-associated activity in pancreatic cancer cells

Virginia Tech researchers from the Department of Biomedical Engineering and Mechanics and the Department of Biochemistry have discovered a characteristic of a common oral bacterium that relocates to pancreatic cancer tumors that may help guide future therapeutic interventions for treatment.

18 Oct 2022

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

During brain development, neurons have to migrate long distances through complex environments until they reach their final destination.

18 Oct 2022

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies that can block metastasis.

18 Oct 2022

Research proposes a set of conditions that could be the starting point for ulcerative colitis

Ulcerative colitis is the most common type of inflammatory bowel disease, characterised by chronic ulcers and inflammation in the colon and rectum.

18 Oct 2022

Does skin inflammation exacerbate COVID-19?

In a new study, researchers discussed inflammation during infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Oct 2022

Study identifies genetic variation that influences lithium-induced neural proliferation

Bipolar disorder, a neuropsychiatric condition that includes manic and depressive episodes, affects about 1% of the population and is strongly influenced by genetics.

18 Oct 2022

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upwards of a billion dollars.

18 Oct 2022

Epigenetic changes related to Parkinson's disease are different in men and women, study says

The epigenetic changes linked to Parkinson's disease – a nervous system disorder that afflicts nearly 1 million Americans – are different in men and women, according to a new Rutgers study published in NPJ Parkinson's Disease.

18 Oct 2022

People with end-stage renal disease and psoriasis do not have increased risk for heart attack

Studies have suggested that psoriasis is an independent risk factor for heart attack in the general population, but investigators have made the surprising finding that in people who also have end-stage renal disease, which shares many risk factors with heart disease, it is not.

18 Oct 2022

What is the function of micronutrients in COVID-19 recovery?

Researchers assessed the function of micronutrients and metabolites derived from gut microbiota in coronavirus disease 2019 (COVID-19) recovery.

18 Oct 2022

B Cell News and Research

Study shows the importance of both obesity and biological sex in COVID-19 outcomes

AI app to read COVID-19 lateral flow tests helps to reduce false results

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

SARS-CoV-2 placentitis may cause placental destruction and stillbirth in women not vaccinated for COVID-19

New research finds microclotting and inflammatory molecule abnormalities in long-COVID

Penn State researchers lay the foundation for precision fabrication of tumor models

Physical exercise improves cardiorespiratory fitness, alleviates adverse effects of cancer treatment

Common oral bacterium promotes tumor progression-associated activity in pancreatic cancer cells

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

Research proposes a set of conditions that could be the starting point for ulcerative colitis

Does skin inflammation exacerbate COVID-19?

Study identifies genetic variation that influences lithium-induced neural proliferation

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

Epigenetic changes related to Parkinson's disease are different in men and women, study says

People with end-stage renal disease and psoriasis do not have increased risk for heart attack

What is the function of micronutrients in COVID-19 recovery?

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