Genetic News and Research

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Genetic mutation associated with autism can impair oxytocin-mediated social behavior

Autism spectrum disorder is a neurodevelopmental condition involving impaired social abilities, and this makes it a fascinating subject for neuroscientists like Prof. Teiichi Furuichi of the Tokyo University of Science who study the neuroscience of social behavior.

19 May 2021

Potent antibody with unique genetic signature and spike recognition mechanism neutralizes SARS-CoV-2

In a new study, researchers used an antibody discovery technology to identify a new potently neutralizing antibody with a unique mode of SARS-CoV-2 recognition. They reported their results on the bioRxiv preprint server.

18 May 2021

SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France

Researchers discovered the first N440K variant and the new E484Q and L452R Indian variants isolated in France in a recent study. They presented the genetic mutations in the isolated genomes and the phylogenetic tree, including these strains among different SARS-CoV-2 clades. This work is posted on the bioRxiv preprint server.

18 May 2021

Higher levels of inflammatory proteins in the blood are associated with aggressive traits

Aggression is common in many neuropsychiatric diseases, such as dementia, autism spectrum disorder, and schizophrenia.

18 May 2021

New coronavirus test can get fast, accurate results from saliva samples

A new coronavirus test can get accurate results from a saliva sample in less than 30 minutes, researchers report in the journal Nature Communications.

18 May 2021

Researchers link “genetic signatures” of bacteria in the human gut to multiple diseases

We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome.

18 May 2021

A promising drug delivery system for therapeutics that shut down harmful genes

Viruses attack the body by sending their genetic code -- DNA and RNA -- into cells and multiplying. A promising class of therapeutics that uses synthetic nucleic acids to target and shut down specific, harmful genes and prevent viruses from spreading is gaining steam.

18 May 2021

Sperm deliver signals to female reproductive tissues to increase the chances of conception

Sperm are generally viewed as having just one action in reproduction - to fertilize the female's egg - but studies at the University of Adelaide are overturning that view.

18 May 2021

Abnormal blood levels of proteins linked to dementia, Alzheimer's disease

The development of dementia, often from Alzheimer's disease, late in life is associated with abnormal blood levels of dozens of proteins up to five years earlier, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health

18 May 2021

Breastfeeding safe and beneficial in SARS-CoV-2 infection

\With the onset of the coronavirus disease 2019 (COVID-19) pandemic, hundreds of millions of people became infected worldwide, including thousands of pregnant women near term. The question of vertical transmission to the infant via the placenta or breast milk was very real, leading to a near-total ban on breastfeeding in this group.

17 May 2021

New insights into how AI will lead to developments in assisted reproductive technology

The 10th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE) has provided exciting insights into likely developments and future possibilities in assisted reproductive technology including artificial intelligence.

17 May 2021

Lifestyle changes can benefit people with high genetic risk for colorectal cancer

People with a high polygenic risk score for colorectal cancer could benefit more at preventing the disease by leading healthy lifestyles than those at lower genetic risk, according to a study by Vanderbilt researchers published in the April issue of The American Journal of Clinical Nutrition.

17 May 2021

Nanotechnology and COVID-19 diagnosis and treatment

The development of nano-biosensors and nanoparticle-based vaccines and medicines has opened a new path toward better management of the coronavirus disease 2019 (COVID-19) pandemic. In a recently published article in the journal ACS Biomaterials Science & Engineering, scientists have reviewed recent advancements in nanotechnology-based diagnostic and therapeutic interventions against human coronaviruses.

17 May 2021

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.

17 May 2021

Retinal scans may provide an early sign of Alzheimer's disease

While it has been said that the eyes are a window to the soul, a new study shows they could be a means for understanding diseases of the brain.

17 May 2021

What can ancient feces tell us about the evolution of the human gut microbiome?

Researchers at the Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center in Boston, Massachusetts, analyzed microbial DNA found in indigenous human paleofeces (desiccated excrement) from dry caves in northern Mexico and Utah. They found that the ancient human gut microbiome is similar to those of modern-day people from non-industrialized populations.

14 May 2021

Supercarriers: Just 2% of SARS-CoV-2 positive people carry 90% of the virus

A new study published in the Proceedings of the National Academy of Sciences shows that the vast majority of the viral load in a community at any given point is present in a very small minority of the infected population, underlining the vast differences in viral loads between individuals.

14 May 2021

A magnetofluidic platform for SARS-CoV-2 variant and respiratory pathogen detection

Recent research published on the medRxiv* server has developed a portable, magnetofluidic cartridge platform, for automated PCR testing in <30 min, for rapid multiplexed screening of pathogens. A multidisciplinary team of researchers at Johns Hopkins University and the Johns Hopkins University School of Medicine developed these cartridges for multiplexed detection of SARS-CoV-2 with distinctive variant mutations or with Influenza A and B.

13 May 2021

Novel nanotechnology could change the lives of people living with cystic fibrosis

World-first nanotechnology developed by the University of South Australia could change the lives of thousands of people living with cystic fibrosis (CF) as groundbreaking research shows it can improve the effectiveness of the CF antibiotic Tobramycin, increasing its efficacy by up to 100,000-fold.

13 May 2021

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

A new study, released as a preprint on the bioRxiv* server, focuses on the lipid molecule called phosphatidic acid (PA), showing its crucial role in the replication of this virus, and thus its potential as a target for therapeutic intervention.

13 May 2021

Genetic News and Research

Genetic mutation associated with autism can impair oxytocin-mediated social behavior

Potent antibody with unique genetic signature and spike recognition mechanism neutralizes SARS-CoV-2

SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France

Higher levels of inflammatory proteins in the blood are associated with aggressive traits

New coronavirus test can get fast, accurate results from saliva samples

Researchers link “genetic signatures” of bacteria in the human gut to multiple diseases

A promising drug delivery system for therapeutics that shut down harmful genes

Sperm deliver signals to female reproductive tissues to increase the chances of conception

Abnormal blood levels of proteins linked to dementia, Alzheimer's disease

Breastfeeding safe and beneficial in SARS-CoV-2 infection

New insights into how AI will lead to developments in assisted reproductive technology

Lifestyle changes can benefit people with high genetic risk for colorectal cancer

Nanotechnology and COVID-19 diagnosis and treatment

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

Retinal scans may provide an early sign of Alzheimer's disease

What can ancient feces tell us about the evolution of the human gut microbiome?

Supercarriers: Just 2% of SARS-CoV-2 positive people carry 90% of the virus

A magnetofluidic platform for SARS-CoV-2 variant and respiratory pathogen detection

Novel nanotechnology could change the lives of people living with cystic fibrosis

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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