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An Omicron wave predicted for England from December 2021 to April 2022

A study, published on the medRxiv* preprint server, focuses on the interaction between Omicron variants and public health interventions in England that promote immunity.

20 Dec 2021

New oral pill for COVID-19 home treatment

As cases and hospitalizations continue to rise in many countries, new treatments are being sought to arrest the progression of the disease, preventing severe illness and death or disability. One such is the small molecule molnupiravir, the focus of a new research paper.

20 Dec 2021

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

A new study posted to the bioRxiv* preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.

20 Dec 2021

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

The arrival of the Omicron (B.1.1.529) variant has brought into question the effectiveness of current COVID-19 treatments in preventing infection and death. New research published in the preprint bioRxiv* server suggests the efficacy of most monoclonal antibody treatments are ineffective against Omicron.

20 Dec 2021

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

The Omicron variant of SARS-CoV-2 may be significantly better than previous variants at evading vaccine-induced antibodies, according to new research from Cambridge - but preliminary evidence suggests it is less likely to cause severe COVID-19 illness in the lungs.

20 Dec 2021

U-M scientists develop a cell-free artificial cortex to study how cells divide

Animal cells are bound by a structure called a cell cortex—and this structure, researchers say, is a bit like a tent.

20 Dec 2021

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Researchers discuss the likely impact on current convalescent therapies and immunity of vaccinated individuals against the SARS-CoV-2 Omicron variant.

20 Dec 2021

UBR7 protein acts as a histone chaperone during DNA replication, study finds

The protein UBR7 acts as a histone chaperone, regulating histone re-deposition at specific sites during DNA replication, according a recent study published in The EMBO Journal.

20 Dec 2021

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Researchers conduct a comprehensive in vitro analysis of relatively unexplored host immune responses during SARS-CoV-2 infection.

20 Dec 2021

White-tailed deer are efficient carriers of SARS-CoV-2

Researchers demonstrate the susceptibility of white-tailed deer to SARS-CoV-2.

20 Dec 2021

New tool provides an unprecedented view of brain cell activity in a synapse

To solve the mysteries of how learning and memory occur, Johns Hopkins Medicine scientists have created a system to track millions of connections among brain cells in mice — all at the same time — when the animals' whiskers are tweaked, an indicator for learning.

20 Dec 2021

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Researchers discuss the sensitivity of the SARS-CoV-2 Omicron variant towards various monoclonal antibodies.

20 Dec 2021

Impact of acute kidney injury associated gene expression in human kidney cells

A new study attempts to perform a comparative single-cell census of human kidneys employing samples from individuals suffering from acute kidney injury and controls without the condition.

20 Dec 2021

Dreaded microbe can silence multiple types of pain, study suggests

Anthrax has a scary reputation. Widely known to cause serious lung infections in humans and unsightly, albeit painless, skin lesions in livestock and people, the anthrax bacterium has even been used as a weapon of terror.

20 Dec 2021

SARS-CoV-2 infection leads to distinct changes in proteomic and peptidomic profiles and posttranslational modifications

A new study indicates that as a result of SARS-CoV-2 infection comprehensive changes in protein processing and regulation occur.

20 Dec 2021

Researchers predict 200% increase in European coronavirus cases as Omicron spreads

New algorithms predict how the Omicron variant will spread across 27 countries in the European Union, the United Kingdom, and Switzerland.

20 Dec 2021

Computational analysis of the effect of SARS-CoV-2 Omicron variant spike protein mutations

A new study highlights the potential evolutionary trade-off observed in the omicron variant, detailing the dynamics of the protein structure, its interactions, and subsequent effects.

20 Dec 2021

A test to identify antibody effectiveness against COVID-19 variants

Since the start of the COVID-19 pandemic, variants have begun to emerge. We spoke to Jacob Heggestad about his rapid test that can detect these variants.

20 Dec 2021

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

A new study expands the understanding of the impact of receiving a prophylactic monoclonal antibody infusion, as well as other variables, on the endogenous immune response to complete COVID-19 immunization.

20 Dec 2021

Study suggests SARS-CoV-2 Omicron variant RBM binding may be weaker than in wild-type

A new study shows that the Omicron variant binds to the ACE2 receptor in a significantly weaker manner than other variants and the wild-type.

20 Dec 2021

Protein C News and Research

An Omicron wave predicted for England from December 2021 to April 2022

New oral pill for COVID-19 home treatment

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

U-M scientists develop a cell-free artificial cortex to study how cells divide

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

UBR7 protein acts as a histone chaperone during DNA replication, study finds

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

White-tailed deer are efficient carriers of SARS-CoV-2

New tool provides an unprecedented view of brain cell activity in a synapse

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Impact of acute kidney injury associated gene expression in human kidney cells

Dreaded microbe can silence multiple types of pain, study suggests

SARS-CoV-2 infection leads to distinct changes in proteomic and peptidomic profiles and posttranslational modifications

Researchers predict 200% increase in European coronavirus cases as Omicron spreads

Computational analysis of the effect of SARS-CoV-2 Omicron variant spike protein mutations

A test to identify antibody effectiveness against COVID-19 variants

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

Study suggests SARS-CoV-2 Omicron variant RBM binding may be weaker than in wild-type

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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