Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

Sanofi, POZEN ink license agreement to commercialize PA8140 and PA32540 tablets in US

Sanofi US and POZEN Inc. announced the signing of an exclusive license agreement for the commercialization of POZEN's proprietary, investigational, coordinated-delivery tablets combining immediate-release omeprazole, a proton pump inhibitor, and enteric-coated aspirin in a single tablet ("PA"), PA8140 and PA32540.

5 Sep 2013

First Edition: September 4, 2013

Todays headlines include reports about how the Balitmore Ravens will be part of the effort to raise public awareness about Maryland's health exchange.

4 Sep 2013

Indicators of poor preoperative health predict risk of major medical complications

For older adults undergoing surgery for spinal stenosis, some simple indicators of poor preoperative health predict a high risk of major medical complications, reports a study in the September 1 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

4 Sep 2013

Free reference and lifestyle tool now available for people affected by paralysis

For the first time, individuals living with paralysis and their caregivers can access the comprehensive Paralysis Resource Guide digitally on their smartphone, Nook, iPad or Kindle. The third edition of this vital resource, compiled and distributed by the Christopher & Dana Reeve Foundation Paralysis Resource Center, is a free reference and lifestyle tool for people affected by paralysis.

4 Sep 2013

Over half of people with hypertension unaware of the condition, very few take adequate treatment

A global study has found that many patients don't know they have hypertension and, even if they do, too few are receiving adequate drug therapy for their hypertension.

4 Sep 2013

Study: Fixed-dose combination medication helps CVD patients

In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual care resulted in significantly improved medication adherence after 15 months and small improvements in systolic blood pressure and low-density lipoprotein cholesterol, according to a study in the September 4 issue of JAMA.

4 Sep 2013

Study: Nearly 12% of Chinese adults have diabetes and about 50% at risk of developing the disease

A study based on a nationally representative sample of adults in China in 2010 indicates that nearly 12 percent of Chinese adults had diabetes and the prevalence of prediabetes was about 50 percent, according to a study in the September 4 issue of JAMA.

4 Sep 2013

NIH-funded study finds zebrafish model may help identify treatments for childhood epilepsy

According to new research on epilepsy, zebrafish have certainly earned their stripes. Results of a study in Nature Communications suggest that zebrafish carrying a specific mutation may help researchers discover treatments for Dravet syndrome (DS), a severe form of pediatric epilepsy that results in drug-resistant seizures and developmental delays.

4 Sep 2013

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Researchers from The University of Manchester and Central Manchester University Hospitals NHS Trust have identified proteins in the blood that could be used to predict whether a woman in her first pregnancy is at increased risk of developing pre-eclampsia.

From The University of Manchester 4 Sep 2013

Obese people with high insulin levels likely to experience better blood vessel function following weight loss

Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have found that among obese people who had lost considerable weight, those with high insulin levels--a marker of insulin resistance in the body--were the most likely to experience better blood vessel function following the weight loss. These findings appear online in the Journal of the American College of Cardiology.

4 Sep 2013

AQUARIUS trial data shows Aliskiren reduced incidents of death, stroke, heart attack

Patients with clogged and hardened arteries who already have their blood pressure under control may benefit from an additional blood pressure-lowering medication, according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C5Research).

4 Sep 2013

More young people show risk factors for common type of strokes

Fifteen percent of the most common type of strokes occur in adolescents and young adults, and more young people are showing risk factors for such strokes, according to a report in the journal Neurology.

4 Sep 2013

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Omecamtiv mecarbil, a cardiac myosin-activator, did not achieve its primary efficacy endpoint in reducing dyspnoea (shortness of breath) in patients with acute heart failure, according to the results of the phase II ATOMIC-AHF (Acute Treatment with Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure) study.

3 Sep 2013

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

Low BMI is a risk factor for CVD in hypertensive patients with diabetes, according to research presented at the ESC Congress today by Dr Takanori Nagahiro from Japan. The findings provide evidence for an obesity paradox in hypertensive patients with glucose intolerance.

3 Sep 2013

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

Researchers from Brigham and Women's Hospital (BWH) have developed a risk score calculation that can help predict which patients with rhabdomyolysis (a condition that occurs due to muscle damage) may be at risk for the severe complication of kidney failure or death.

3 Sep 2013

Proteins in blood could predict woman at increased risk of developing pre-eclampsia

3 Sep 2013

Respiratory infection antibiotic guidance often ignored

Researchers from the USA say that more must be done to improve adherence to guidelines for antibiotic prescriptions for upper respiratory tract infections, sinusitis, and pharyngitis.

2 Sep 2013

BP variability a long-term challenge

Blood pressure variability over the long term predicts mortality among patients receiving treatment for hypertension, a study shows.

2 Sep 2013

NPS MedicineWise reiterates safety messages around newer oral anticoagulants

NPS MedicineWise is reiterating safety messages around the newer anticoagulants dabigatran (Pradaxa) and apixaban (Eliquis) following their PBS listing for preventing stroke on 1 September 2013 – and again for rivaxabaran (Xarelto) which was PBS listed in August for the same purpose.

2 Sep 2013

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Metabolically healthy women have the same cardiovascular disease risk regardless of their BMI, according to research presented at the ESC Congress today by Dr S-ren Sk-tt Andersen and Dr Michelle Schmiegelow from Denmark.

2 Sep 2013

Stroke News and Research

Further Reading

Sanofi, POZEN ink license agreement to commercialize PA8140 and PA32540 tablets in US

First Edition: September 4, 2013

Indicators of poor preoperative health predict risk of major medical complications

Free reference and lifestyle tool now available for people affected by paralysis

Over half of people with hypertension unaware of the condition, very few take adequate treatment

Study: Fixed-dose combination medication helps CVD patients

Study: Nearly 12% of Chinese adults have diabetes and about 50% at risk of developing the disease

NIH-funded study finds zebrafish model may help identify treatments for childhood epilepsy

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Obese people with high insulin levels likely to experience better blood vessel function following weight loss

AQUARIUS trial data shows Aliskiren reduced incidents of death, stroke, heart attack

More young people show risk factors for common type of strokes

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

Proteins in blood could predict woman at increased risk of developing pre-eclampsia

Respiratory infection antibiotic guidance often ignored

BP variability a long-term challenge

NPS MedicineWise reiterates safety messages around newer oral anticoagulants

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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