Efficacy News and Research

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CDC recommends new vaccine for shingles

Last month a U.S. Food and Drug Administration (FDA) advisory panel had voted 11 to 0 approving a shingles vaccine for its use in adults aged 50 and over. The panel unanimously accepted the safety and efficacy of the vaccine and thus GlaxoSmithKline’s Shingrix.

25 Oct 2017

APC gene mutations play dual role in development of colorectal cancer, research suggests

Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm the immune system, leaving it unable to tackle inflammation of the colonic mucosa.

24 Oct 2017

Study identifies protein that plays crucial role in diabetic retinopathy

For millions of Americans, their world is dissolving into an unrecognizable blur. Diabetic retinopathy is an eye disease affecting one-third of the estimated 30 million Americans who struggle with diabetes. As the patients' vision slowly fades, it never recovers and few treatments are available.

24 Oct 2017

Study offers solution to protect against vaccine-enhanced respiratory disease

Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory disease that results when patients given an early form of a vaccine for respiratory syncytial virus (RSV) are exposed to RSV, according to a study led by Georgia State University.

23 Oct 2017

Study shows link between symptom burden and use of health care services in advanced cancer patients

Hospitalized patients with advanced cancer who report more intense and numerous physical and psychological symptoms appear to be at risk for longer hospital stays and unplanned hospital readmissions.

23 Oct 2017

RAND researchers estimate health care savings over next decade from biosimilars

Introducing "biosimilar" versions of complex biologic drugs used to treat illnesses such as cancer and rheumatoid arthritis could cut health care spending in the United States by $54 billion over the next decade, according to new analysis from the RAND Corporation.

23 Oct 2017

Osteocytes play crucial role as major source of RANKL during orthodontic tooth movement

Tokyo Medical and Dental University research team demonstrated that osteocytes have a crucial role in orthodontic tooth movement as the major source of receptor activator of nuclear factor-κB ligand (RANKL), a protein crucial to bone remodeling.

23 Oct 2017

Adipose-derived stem cell clinical trial focuses on non-healing leg wounds

Sanford Health is launching its second adipose-derived stem cell clinical trial - this one to focus on non-healing leg wounds.

20 Oct 2017

Small RNA molecules trigger cancer cells to commit suicide

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

19 Oct 2017

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element can be a potent force against cancer.

17 Oct 2017

New imaging system offers better way to monitor brain changes from Alzheimer's in mouse models

An estimated 5.5 million Americans live with Alzheimer's disease, a type of dementia that causes problems with memory, thinking and behavior. Although treatments can slow the worsening of symptoms, scientists are still working to better understand the neurodegenerative disease so that curative and preventative medicines can be developed.

17 Oct 2017

Scientists receive critical funding to study treatments for three deadly cancers

Immunotherapy for leukemia patients has been nothing short of a miracle. Now scientists hope to use that science and other forms of gene therapy to tackle three of the deadliest forms of cancer: glioblastoma (brain cancer), sarcoma (bone cancer) and ovarian cancer.

17 Oct 2017

Dietary combination transforms lethal breast cancers into highly treatable form

Researchers at the University of Alabama at Birmingham have found a dietary combination that transforms the most lethal of all breast cancers into a highly treatable breast cancer.

17 Oct 2017

Magic mushrooms chemical Psilocybin for treatment of hard-to treat depression

A new study from UK has found efficacy of psilocybin – a chemical found in “magic mushrooms”, in severe depression. The study involved 19 patients with severe depression. The patients took the psilocybin and around half of them improved and reported maintained improvement after 5 weeks of therapy. The patients however also received psychological care along with the treatment.

16 Oct 2017

Efficacy News and Research

CDC recommends new vaccine for shingles

APC gene mutations play dual role in development of colorectal cancer, research suggests

Study identifies protein that plays crucial role in diabetic retinopathy

Study offers solution to protect against vaccine-enhanced respiratory disease

Study shows link between symptom burden and use of health care services in advanced cancer patients

RAND researchers estimate health care savings over next decade from biosimilars

Osteocytes play crucial role as major source of RANKL during orthodontic tooth movement

Adipose-derived stem cell clinical trial focuses on non-healing leg wounds

Small RNA molecules trigger cancer cells to commit suicide

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

New imaging system offers better way to monitor brain changes from Alzheimer's in mouse models

Scientists receive critical funding to study treatments for three deadly cancers

Dietary combination transforms lethal breast cancers into highly treatable form

Magic mushrooms chemical Psilocybin for treatment of hard-to treat depression

Wake Forest Baptist scientists win grant to develop more effective treatments for brain cancer

AASM’s new position statement describes clinical use of home sleep apnea test

Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome

New study uncovers 13 previously-unknown genetic risk variants for restless legs syndrome

Ebola vaccine that provides a year’s worth of protection developed

Birth control method for men by gene editing

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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