Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Unraveling the mysteries of post-acute infection syndromes

In recent years, doctors and scientists are increasingly studying long-lasting illnesses that begin after someone recovers from an infection.

1 Aug 2025

New research reveals why fiber-rich diets fuel you better than refined foods

This study quantifies how much energy the human body harvests from gut microbial fermentation of dietary fiber, integrating bacterial physiology, diet, and metagenomic data. Results reveal that dietary fiber, not microbiome composition, mainly determines the amount of short-chain fatty acids absorbed, impacting daily energy and metabolic health.

31 Jul 2025

Can stacking creatine and β-alanine give you extra gains? Here’s what science says

Co-supplementation with creatine and β-alanine may enhance high-intensity exercise performance, especially in repeated short bursts. However, it offers no additional benefit over creatine alone for maximal strength, aerobic capacity, or body composition.

30 Jul 2025

Dual targeting of lipid kinases offers hope against emerging viruses

Lipid kinases are enzymes that play a critical role in both cell signalling and membrane trafficking by phosphorylating lipid molecules in the body.

14 Jul 2025

Virginia Tech researchers explore creatine therapy for brain health

Creatine is popularly known as a muscle-building supplement, but its influence on human muscle function can be a matter of life or death.

9 Jul 2025

Reversing immune fatigue offers new hope for cancer treatment

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

7 Jul 2025

ADA2 regulates inflammation through lysosomal and extracellular mechanisms

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and activation.

7 Jul 2025

Mitochondria depletion in stem cells offers insights into cellular energy and evolution

By using a genetic technique developed at UT Southwestern Medical Center that forces cells to rid themselves of mitochondria, researchers are gaining new insights into the function of these critical organelles.

7 Jul 2025

Brain cells can burn fat to fuel activity

While glucose, or sugar, is a well-known fuel for the brain, Weill Cornell Medicine researchers have demonstrated that electrical activity in synapses—the junctions between neurons where communication occurs—can lead to the use of lipid or fat droplets as an energy source.

1 Jul 2025

Study uncovers how inflammation in brain blood vessels exacerbates damage in vascular dementia

A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional recovery in mice.

1 Jul 2025

Targeting mitochondrial dynamics to combat breast cancer metastasis

Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to its aggressive nature and limited therapeutic targets.

27 Jun 2025

Experimental drug promotes weight loss by heating fat instead of suppressing appetite

An article published in the journal Nature Metabolism presents an experimental drug that stimulates adipose tissue cells to produce heat through a process known as thermogenesis, thereby promoting weight loss.

24 Jun 2025

Could a diabetes drug be the key to stopping Alzheimer’s?

Investigating tirzepatide's role in Alzheimer's reveals its potential to improve brain function and reduce inflammation, linking diabetes and neurodegeneration.

17 Jun 2025

Understanding the role of astrocytes in depression and neuroinflammation

Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in activities that were previously associated with happiness.

13 Jun 2025

Inhibiting cancer cells' energy source with natural acid ester

Looking to nature for answers to complex questions can reveal new and unprecedented results that can even affect cells on molecular levels.

10 Jun 2025

What happens to your body and mind during a five-day water fast?

A five-day water-only fast led to significant weight, fat, and lean muscle loss in middle-aged women, along with improved mood and marked changes in metabolic and inflammatory markers. The study also found that psychological traits like emotional intelligence and impulsivity influenced the amount of fat and muscle lost during fasting.

9 Jun 2025