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PRDM16 regulates the balance between proliferation and maturation in human cardiomyocytes

Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in cardiovascular biology.

7 Aug 2026

Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target

Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome.

7 Aug 2026

Severe COVID-19 reactivates dormant viruses and may leave a lasting viral signature

A longitudinal study of 1,154 hospitalized COVID-19 patients found widespread reactivation of chronic Herpesviridae and Anelloviridae, with distinct viral patterns linked to disease severity, inflammation, and clinical outcomes. Anelloviridae also persisted during convalescence and were associated with physical deficits in long COVID, although the study did not establish causation.

7 Aug 2026

Meningococcal B vaccine linked to lower gonorrhoea risk

The meningococcal B (MenB) vaccine could provide protection against more than one disease, with new research linking it to a significant reduction in the risk of gonorrhoea in young Territorians.

6 Aug 2026

First-trimester protein intake linked to lower odds of small-for-gestational-age birth

A secondary analysis of 7,067 nulliparous participants found that first-trimester protein intake of 0.8 to less than 1.1 g/kg/day was associated with 22% lower adjusted odds of delivering an SGA infant than intake of at least 1.1 g/kg/day. The association was exploratory, with no dose-response pattern and no confirmation in sensitivity analyses.

6 Aug 2026

Hypothyroidism linked to higher risk of obstructive sleep apnea

According to a study conducted in Brazil by researchers at the Federal University of São Paulo (UNIFESP) with participants from the São Paulo Epidemiological Sleep Study (EPISONO 2018), people with hypothyroidism experience a higher frequency and severity of obstructive sleep apnea (OSA).

5 Aug 2026

Physical activity linked to lower stroke and death risk in adults with atrial fibrillation

Being physically active was linked to a lower risk of stroke and death for adults with atrial fibrillation, or AFib, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

5 Aug 2026

Tadalafil may increase glaucoma risk in men with enlarged prostates

An erectile dysfunction drug that is also used to treat symptoms like sudden urgency and frequency, which are associated with an enlarged prostate in men, may heighten the risk of the serious eye condition, glaucoma, finds a large comparative study published online in the British Journal of Ophthalmology.

4 Aug 2026

Study links AI companions to increased loneliness and lower well-being

AI companions are becoming increasingly popular, with millions of users forming deep connections with persona-based chatbots and simulated AI partners.

4 Aug 2026

AI tool helps customize radiopharmaceutical therapy dosing

Radiopharmaceutical therapy (RPT) has made great strides over the last 50 years, having only recently received FDA approval to treat prostate cancer. But despite the progress-and billions of dollars of industry investments-one area that has lagged behind is dosing, which is still one-size-fits-all.

4 Aug 2026

Child-friendly lung test identifies subtle abnormalities before stem cell transplant

As spirometry requires coordinated deep breathing and can be challenging for children to perform, researchers from the USA, as part of the TRANSPIRE study investigating lung complications in children undergoing hematopoietic stem cell transplantation (HSCT), explored the potential of oscillometry, a simple and child-friendly lung function test.

3 Aug 2026

New ultrasound technique breaches blood brain barrier to treat gliomas

In a promising sign for the potential of focused sound waves to improve care for brain tumors, UVA Health researchers have determined that tumors called gliomas may be even more receptive to targeted drug delivery than normal brain tissue.

30 Jul 2026

Looking babies in the eyes may help them learn

Research reveals that direct eye contact enhances language learning in infants through adult-to-infant neural connectivity, highlighting its social relevance.

30 Jul 2026

When sleep changes in women over 80, it may signal more than aging

Researchers tracked sleep-wake changes over five years in 704 women in their 80s and 90s using wrist actigraphy. Declining nighttime sleep and increasing 24-hour sleepiness were associated with approximately twice the hazard of all-cause mortality.

29 Jul 2026

Low-fat diet lowers dietary glycation compounds for years in postmenopausal women

Researchers analyzing dietary data from 40,209 postmenopausal women found that a low-fat pattern emphasizing fruits, vegetables, and grains was associated with sustained reductions in estimated dietary advanced glycation end-product intake over approximately seven years. The findings suggest broad dietary changes may lower dAGE intake without specific cooking instructions, although the study did not measure biological AGE exposure or determine whether the reductions influenced breast cancer outcomes.

29 Jul 2026

We underestimate how much personality changes with age, study finds

Researchers compared beliefs from 887 US adults with modeled lifespan trajectories from 166,971 participants across eight longitudinal studies. Population-average Big Five traits changed as much as or more than many health, financial, psychological, and social measures, despite people perceiving personality as unusually stable.

29 Jul 2026