Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

CDCA7 identified as key player in hemimethylation sensing

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked.

28 Aug 2024

Study illuminates CDCA7's role in DNA methylation

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism.

27 Aug 2024

Innovative drug reduces inflammation in rats by inhibiting neutrophil activation

A newly developed compound that reduces harmful inflammation in rats caused by overactive neutrophils shows great potential as a safer treatment for various inflammatory diseases in humans.

23 Aug 2024

Common fatty acid could improve treatment of recurrent bacterial vaginosis infections

Researchers investigated oleic acid as a potential treatment to inhibit Lactobacillus iners dominance in bacterial vaginosis.

22 Aug 2024

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Researchers found that valproic acid (VPA), especially when combined with DHA, significantly reduces SARS-CoV-2 infection rates and severity, potentially activating antiviral mechanisms. Epidemiologic data support VPA's role in reducing COVID-19 severity and hospitalization rates.

6 Aug 2024

Climate change-driven migrations worsen infectious diseases in vulnerable regions

Climate change-driven migrations increase infectious disease risks by spreading pathogens and overcrowding vulnerable regions, demanding urgent, targeted interventions.

1 Aug 2024

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications.

24 Jul 2024

40% of US cancer cases linked to lifestyle choices

Nearly 40% of cancer cases and 44% of cancer deaths in 2019 were due to modifiable risk factors, with cigarette smoking as the leading cause. This study highlights the potential to significantly reduce cancer burden through lifestyle changes.

14 Jul 2024

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Chromosome 18q deletion (18q del) syndromeis a rare genetic condition disorder, affecting approximately 1 in 40,000 to 55,000 individuals, caused by the deletion of genetic material on the long arm of chromosome 18.

11 Jul 2024

Study: 40% of cancer cases in the U.S. attributable to modifiable risk factors

A new study led by researchers at the American Cancer Society (ACS) finds four in 10 cancer cases and about one-half of all cancer deaths in adults 30 years old and older in the United States (or 713,340 cancer cases and 262,120 cancer deaths in 2019) could be attributed to modifiable risk factors, including cigarette smoking, excess body weight, alcohol consumption, physical inactivity, diet, and infections.

11 Jul 2024

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Researchers reveal both direct and indirect mechanisms of SARS-CoV-2-induced lymphopenia, highlighting the role of CD147 and alternative viral entry routes into T cells.

8 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

New HIV test targets neglected strains in global cure hunt

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa - a vital tool in the search for an HIV cure that will benefit patients around the world.

3 Jul 2024

Immunodeficiency News and Research

Further Reading

CDCA7 identified as key player in hemimethylation sensing

Study illuminates CDCA7's role in DNA methylation

Innovative drug reduces inflammation in rats by inhibiting neutrophil activation

Common fatty acid could improve treatment of recurrent bacterial vaginosis infections

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Climate change-driven migrations worsen infectious diseases in vulnerable regions

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

40% of US cancer cases linked to lifestyle choices

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Study: 40% of cancer cases in the U.S. attributable to modifiable risk factors

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

New HIV test targets neglected strains in global cure hunt

Early detection of aggressive multiple myeloma through molecular analysis

Human milk banks improve infant health but can't fully replace mother's milk

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Rising syphilis cases highlight gaps in public knowledge on symptoms and treatment

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Gene therapy trial: restored hearing in children with hereditary deafness

New strategy targets rare B cells for effective HIV vaccine development

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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