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Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

The study tracks the long-term kinetics of antibody responses to SARS-CoV-2 after vaccination and infections in New York healthcare workers from 2020 to 2023. It reveals that antibody waning is slower after booster shots, but there's an upper limit to antibody levels, which gradually lowers with repeated SARS-CoV-2 exposures and vaccinations.

31 Aug 2023

Cracking the code on post-vaccine COVID protection

The study investigates the relationship between antibody levels and behavioral factors in 176 adults vaccinated with Pfizer's BNT162b2, finding that higher levels of specific antibodies correlate with greater protection against symptomatic COVID-19. It also suggests that current commercial assays may need reformatting for better risk prediction.

31 Aug 2023

New insights: Gut microbiome alterations linked to rising allergic disease prevalence

The association between the maturation of the infant gut microbiome and the infant immune system.

30 Aug 2023

West Nile virus surges to highest incidence since 2012

Researchers discuss the surveillance of West Nile virus and other arboviruses in the United States.

29 Aug 2023

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Researchers investigated immunologic and clinical findings indicative of SARS-CoV-2 exposure among individuals with postviral syndrome.

29 Aug 2023

Study finds that germline-encoded specificities cannot always predict the trajectory of B-cell responses

Researchers used computational simulations and experiments to investigate how genetic variations encoded in the germline impact B-cell responses.

29 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

Study shows that CD98hc can be targeted to deliver biotherapeutics in brain

Researchers engineered and characterized a blood-brain barrier transport vehicle targeting the CD98 heavy chain of heterodimeric amino acid transporters.

24 Aug 2023

Doctors and patients try to shame insurers online to reverse prior authorization denials

Sally Nix was furious when her health insurance company refused to pay for the infusions she needs to ease her chronic pain and fatigue.

23 Aug 2023

Current and future strategies for vaccinating against invasive pneumococcal disease

Researchers reviewed the immune mechanisms employed by existing vaccines for invasive pneumococcal disease.

23 Aug 2023

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

COVID-19 can increase the risk of various autoimmune diseases; however, this risk appears to be mitigated by vaccination against COVID-19.

21 Aug 2023

Glycans and GBPs: How their interplay shapes immunity in infection and autoimmune diseases

Researchers discuss the regulatory roles of glycans and glycan-binding proteins in modulating immune responses.

21 Aug 2023

Study suggests antibodies triggered by COVID-19 mRNA vaccination may depend on prior infection history

Researchers evaluated distinct immune responses to mRNA and vector-based COVID-19 vaccines and natural SARS-CoV-2 infections.

17 Aug 2023

Study evaluates differences in humoral immune response against SARS-CoV-2 in infants versus mothers

Researchers comparatively evaluated humoral immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among infants and their mothers.

16 Aug 2023

Study explores the challenges of the clinical diagnoses of acute exacerbation of chronic obstructive pulmonary disease

A recent study evaluated the clinical, laboratory, and radiographic characteristics of acute exacerbations of chronic obstructive pulmonary disease (AECOPD).

16 Aug 2023

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Researchers presented a scalable lipid nanoparticle production (SCALAR) platform to develop SARS-CoV-2 mRNA lipid nanoparticle vaccines.

15 Aug 2023

Study yields new knowledge about genes responsible for IgG production and release

A collaboration led by UCLA and the Seattle Children's Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type of antibody in the human body.

14 Aug 2023

Olfactory dysfunction following mild SARS-CoV-2 infection associated with neurological changes in structural connectivity

Researchers investigated the changes in olfactory bulb volume and structural connectivity of the brain in patients with olfactory dysfunction following mild SARS-CoV-2.

14 Aug 2023

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Scientists have developed a lymph node-targeted multi-epitope subunit vaccine that induces strong humoral and cellular immune responses against EBV in mice.

14 Aug 2023

Does convalescent serum treatment lower mortality in SARS-CoV-2-infected individuals?

Researchers evaluated the impact of convalescent serum therapy on all-cause mortality among COVID-19 patients.

14 Aug 2023

Immunoglobulin News and Research

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

Cracking the code on post-vaccine COVID protection

New insights: Gut microbiome alterations linked to rising allergic disease prevalence

West Nile virus surges to highest incidence since 2012

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Study finds that germline-encoded specificities cannot always predict the trajectory of B-cell responses

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Study shows that CD98hc can be targeted to deliver biotherapeutics in brain

Doctors and patients try to shame insurers online to reverse prior authorization denials

Current and future strategies for vaccinating against invasive pneumococcal disease

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

Glycans and GBPs: How their interplay shapes immunity in infection and autoimmune diseases

Study suggests antibodies triggered by COVID-19 mRNA vaccination may depend on prior infection history

Study evaluates differences in humoral immune response against SARS-CoV-2 in infants versus mothers

Study explores the challenges of the clinical diagnoses of acute exacerbation of chronic obstructive pulmonary disease

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Study yields new knowledge about genes responsible for IgG production and release

Olfactory dysfunction following mild SARS-CoV-2 infection associated with neurological changes in structural connectivity

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Does convalescent serum treatment lower mortality in SARS-CoV-2-infected individuals?

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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