Inflammasome News and Research

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Surprising new role for a key immune regulator revealed

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

3 Aug 2023

The roles and plausible mechanisms of pyroptosis in renal inflammation and fibrosis

Researchers summarize available data on pyroptosis in the context of renal fibrosis, as well as its prevention and treatment.

1 Aug 2023

Researchers discover a protein that plays critical roles in alerting the body to a bacterial infection

A team led by researchers at Massachusetts General Hospital (MGH) has discovered a protein that plays critical roles in alerting the body to a bacterial infection and initiating an effective immune response to fight back against the invasion.

27 Jul 2023

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses.

16 Jun 2023

Biologists discover a previously unknown way that the immune system detects viruses

Inflammasomes make up an intricate system of molecular sensors that our bodies use to sound an alarm when an infection occurs.

8 Jun 2023

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Study findings offer hope for the development of novel treatments for leishmaniasis

In an article published in the journal Nature Communications, researchers at the University of São Paulo (USP) in Brazil show how protozoans of the genus Leishmania that cause leishmaniasis manipulate a protein that plays an essential role in the organism's defense in order to continue to replicate, preventing the body from vanquishing the disease.

23 May 2023

Ketogenic diet: A metabolic makeover boosting immunity and battling inflammation

A recent study discusses alterations in the human metabolic fingerprint associated with the keto diet.

8 May 2023

How do viral infections cause autoimmune diseases?

Researchers describe the pathological mechanisms of virus-induced autoimmune diseases.

28 Mar 2023

Candida auris escapes innate immunity through metabolic reprogramming

A team of scientists from Australia and Israel demonstrates that Candida auris, a fungus associated with life-threatening and drug-resistant infections, escapes the host's innate immune response by destroying macrophages through metabolic reprogramming. The fungus is also capable of escaping antimicrobial inflammatory response.

23 Mar 2023

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

Tyrosine kinase inhibitors are a type of targeted cancer medicine that can attack specific types of cancer cells and prevent them from multiplying.

17 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Researchers assessed the impact of an anti-CD3 monoclonal antibody called Foralumab in COVID-19 treatment.

9 Mar 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Emad Ibrahim, M.D., director of the Male Fertility Research Program at The Miami Project to Cure Paralysis and the clinical andrology lab at the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine, has been awarded a $3.25 million grant by the Department of Defense for a four-year study on the use of an oral medication to treat an infertility issue that affects most men with spinal cord injury.

27 Feb 2023

Inflammasome News and Research

Surprising new role for a key immune regulator revealed

The roles and plausible mechanisms of pyroptosis in renal inflammation and fibrosis

Researchers discover a protein that plays critical roles in alerting the body to a bacterial infection

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Biologists discover a previously unknown way that the immune system detects viruses

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Study findings offer hope for the development of novel treatments for leishmaniasis

Ketogenic diet: A metabolic makeover boosting immunity and battling inflammation

How do viral infections cause autoimmune diseases?

Candida auris escapes innate immunity through metabolic reprogramming

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Mass spectrometry-based identification of COVID-19 biomarkers

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

UVA research provides new insight into common causes of vision loss

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Understanding the relationship between SARS-CoV-2 infection and periodontitis

A machine-learning approach to identify asthma subtypes based on molecular signatures

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

Industry Focus eBook - Cell biology (5th edition) eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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