Kidney Failure News and Research

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Early treatment withdrawal offers safety and savings for patients with rare kidney disease

Early withdrawal of a treatment for patients with a rare kidney disease is possible without relapse, safer for patients and saves the NHS millions of pounds, new research has revealed.

7 Aug 2025

Suppression of cdc42 activity could be a promising therapy for nephrotic syndrome

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression of cdc42 activity could be a promising therapy for nephrotic syndrome.

6 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

New Swiss study probes lingering fatigue after Legionnaires' disease

Researchers in Switzerland launched the LongLEGIO study to compare the long-term health impacts of Legionnaires’ disease and other bacterial pneumonias. Baseline data reveal key differences in comorbidities and quality of life between the groups, with follow-up underway.

4 Aug 2025

Addressing avoidable hospitalizations in terminally ill nursing home residents

Hospitalizations and emergency department (ED) visits can be distressing and costly for nursing home residents – especially those who are severely impaired or terminally ill. Despite their vulnerability, these individuals are frequently transferred to hospitals, even though up to 40% of such transfers over the past 25 years are considered potentially avoidable by health care professionals.

25 Jul 2025

AI tool helps doctors predict hospital death risk in cirrhosis patients

Predicting who might die while in the hospital is one of the hardest challenges for doctors caring for people with serious liver disease.

24 Jul 2025

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide significant benefits for cardiovascular, kidney, liver, joint, and sleep-related diseases. These effects extend beyond weight loss, suggesting anti-inflammatory mechanisms with broad potential for managing chronic diseases.

22 Jul 2025

Maybe it’s not just aging. Maybe it’s anemia.

Gary Sergott felt weary all the time. "I'd get tired, short of breath, a sort of malaise," he said. He was cold even on warm days and looked pale with dark circles under his eyes.

17 Jul 2025

New analysis reveals widespread progression of CKM syndrome across the U.S.

One in three adults in the U.S. has three or more risk factors for a newly recognized but increasingly common condition: cardiovascular-kidney-metabolic (CKM) syndrome.

11 Jul 2025

Looking for a natural way to lower blood pressure? Whole grains might be the answer

A new meta-analysis of prospective cohort studies found that higher whole grain intake is linked to a significantly lower risk of developing hypertension, with a 26% risk reduction observed between highest and lowest intake groups. In contrast, refined grain consumption showed no clear association with hypertension risk.

2 Jul 2025

Study reveals persistent inequalities in children's access to kidney transplants across the UK

New research, presented at the ESOT Congress 2025, reveals persistent inequalities in children's access to life-saving kidney transplants across the UK.

1 Jul 2025

Study finds no evidence to suggest mild COVID-19 may cause long-term kidney damage

A new study of over 13 million people in England has found no evidence to suggest mild COVID-19 infection may cause long-term kidney damage.

19 Jun 2025

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Understanding why older Americans switch Medicare Advantage plans

More than half of older Americans now get their Medicare coverage through an insurance company's Medicare Advantage plan.

3 Jun 2025

Necrosis may hold the key to unlocking longevity and space health solutions

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study from researchers at UCL, drug discovery company LinkGevity and the European Space Agency (ESA).

29 May 2025

Silence on E. coli outbreak highlights how Trump team’s changes undermine food safety

Colton George felt sick. The 9-year-old Indiana boy told his parents his stomach hurt. He kept running to the bathroom and felt too ill to finish a basketball game.

28 May 2025

Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles

Red blood cell-derived extracellular vesicles in type 2 diabetes are actively taken up by the endothelium, transferring the enzyme arginase-1 and triggering oxidative stress. This mechanism helps explain vascular complications in diabetes and offers new targets for therapeutic intervention.

19 May 2025

Egg white proteins show promise in naturally lowering blood pressure

Hypertension is a major public health concern, affecting millions worldwide and increasing the risk of heart disease, stroke, and kidney failure.

1 May 2025

One RSV shot cuts severe lung infections in older adults for three seasons, trial shows

A phase 3 trial involving nearly 25,000 older adults across 17 countries found that a single dose of the RSVPreF3 OA vaccine reduced RSV-related lower respiratory tract disease by 63% over three seasons. Protection remained substantial despite waning, with similar efficacy to a two-dose regimen and a favorable safety profile.

23 Apr 2025