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Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Neoantigen discovery sheds light on cancer immunogenicity

Researchers reported a proteogenomic approach to investigate fresh solid melanoma tumor material.

4 Aug 2023

$New facile strategy for proteome analysis using ultracentrifugation fractionation$

New facile strategy for proteome analysis using ultracentrifugation fractionation

Urine is one of the attractive sources for early and sensitive biomarker discovery since it can accumulate and reflect changes in the human body while being collected non-invasively.

16 Jun 2023

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Researchers evaluated the presence of coronavirus disease 2019 (COVID-19) drugs in river water.

8 Jun 2023

Shaping the human metabolome: the impact of a ketogenic diet

Researchers explored how the human metabolic fingerprint changes with a ketogenic diet (KD).

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Unlocking gut health: How indoor environment impacts the microbiota balance

Research paper highlights the importance of a diverse and balanced gut microbiota for human health, while emphasizing the need for further understanding of the impact of indoor microbiome and metabolites on gut microbiota.

21 May 2023

A machine-learning approach for the early diagnosis of Parkinson's disease

Scientists discuss a machine learning-based tool that can detect Parkinson's disease years before the first onset of symptoms.

11 May 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

Researchers assessed the different impacts of diet on the gut microbiome.

15 Feb 2023

New method for capturing moments during protein translation

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS—short for peptidyl-tRNA enrichment using organic extraction and silica adsorption.

10 Feb 2023

LC/MS News and Research

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Neoantigen discovery sheds light on cancer immunogenicity

New facile strategy for proteome analysis using ultracentrifugation fractionation

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Shaping the human metabolome: the impact of a ketogenic diet

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Unlocking gut health: How indoor environment impacts the microbiota balance

A machine-learning approach for the early diagnosis of Parkinson's disease

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

High-resolution mass spectrometric rapid identification of Candida auris

Mass spectrometry-based identification of COVID-19 biomarkers

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

New method for capturing moments during protein translation

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Isolated monoclonal antibodies targeting SARS-CoV-2 S1/S2 cleavage effective against Delta and Omicron

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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