Motor Neuron Disease News and Research

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Promising diagnostic, prognostic tools for onset and progression of ALS

Amyotrophic lateral sclerosis is a motor neuron disease with rampant progression and that it is typically fatal within 5 years of prognosis.

5 Apr 2019

Ezogabine treatment reduces motor neuron excitability in ALS patients, study shows

Brian Wainger, MD, PhD, of the Healey Center for ALS at Massachusetts General Hospital presented initial, top-level results of a recently completed phase 2 clinical trial of ezogabine (also called retigabine) on December 9 at the Motor Neurone Disease Association annual meeting in Glasgow, Scotland.

11 Dec 2018

Scientist uncovers hidden region of the human brain

A world-renowned expert has announced the discovery of a hidden brain region in humans that may be what differentiates humans from monkeys and other animals.

23 Nov 2018

Scientists reveal novel brain network linked to pain in Parkinsonism

Scientists have revealed a novel brain network that links pain in Parkinson's disease (PD) to a specific region of the brain, according to a report in the journal eLife.

28 Aug 2018

Studies on fruit flies reveal new findings of how neurons in the brain function

Studies of the song of the fruit flies reveal new findings of how the neurons in the brain function. These results can be used to uncover new knowledge on how brains in general function which in the longer term may have medical significance.

25 Aug 2018

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

There is new hope for the treatment of Alzheimer's and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Study unravels how nuclear pore complexes transport mRNAs out of the nucleus

Standing guard between a cell's nucleus and its main chamber, called the cytoplasm, are thousands of behemoth protein structures called nuclear pore complexes, or NPCs.

13 Jun 2018

New discovery could have significant implications in brain aging and cancers

Scientists at the University of Sheffield have discovered what keeps the perfect balance of breaks and repairs in our DNA - something which could help improve the success of chemotherapy and combat neurodegeneration associated with aging.

13 Jun 2018

New way of delivering gene therapy shows promise in treating brain conditions

Researchers from the School of Immunology & Microbial Sciences have engineered a novel way of delivering gene therapy that they hope will mean scientists and doctors can target areas of the brain that were previously difficult to reach.

5 Jun 2018

Researchers work together to solve mystery of motor neuron death in ALS patients

As the old adage goes, 'two heads are better than one'. With the development of new technologies and increasingly specialist expertise, ground-breaking science needs to be a team effort.

25 May 2018

Old drug offers new hope for treatment of MND

An international study led by biochemists at the University of Liverpool has shown that the drug-molecule ebselen can correct many of the toxic characteristics of a protein that causes some cases of hereditary motor neurone disease (MND).

17 May 2018

Specific immune cells may help slow progression of ALS, research shows

New research into Amyotrophic Lateral Sclerosis (ALS) - also known as motor neuron disease - shows that specific immune cells may help slow progression of the disease, an important step towards developing new therapies to treat patients.

22 Mar 2018

Scientists discover basic molecular mechanism that helps understand how ALS works

It took eight long years of research, but now an international team led by neuroscientists at Université de Montréal has discovered a basic molecular mechanism that better helps understand how Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), works.

19 Mar 2018

Plymouth researcher receives grant to further investigate causes of hereditary neuro-tumors

The University of Plymouth will be continuing its research into the advancement of neuro-tumor treatments thanks to more than £100,000 from Great Ormond Street Hospital Children's Charity and Sparks, the medical research charity.

5 Mar 2018

Research brings scientists one step closer to understanding development of ALS

University of Michigan-led research brings scientists one step closer to understanding the development of neurodegenerative disorders such as ALS.

8 Dec 2017

Researcher discovers enzyme pathway involved in ALS pathogenesis

It is estimated that between 14,000 and 15,000 Americans have amyotrophic lateral sclerosis (ALS), according to the National Institutes of Health. Symptoms of ALS, also known as Lou Gehrig's disease, may be subtle at first but develop into more obvious muscle weakness and paralysis.

5 Dec 2017

Nerve cell findings provide unique insights into neuromuscular conditions

The findings relate to a type of cell connection that allows electrical and chemical messages to flow from nerve to muscle cells, enabling motion.

29 Nov 2017

Report: Global burden of neurological disorders in today’s world

Globally, the burden of neurological disorders (Alzheimer's disease, Parkinson's disease, stroke, epilepsy etc) has increased substantially over the past 25 years.

13 Oct 2017

Researchers identify new disease gene for early-onset axonal neuropathy and mild intellectual disability

Research group from the University of Helsinki, Finland, has identified a new disease gene for early-onset axonal neuropathy and mild intellectual disability through an international research network, which was brought together by "Tinder for geneticists".

20 Jun 2017