Necrosis News and Research

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Artificial lung keeps patient alive after lung removal

Researchers evaluate the effectiveness of a novel extracorporeal total artificial lung system to enable bilateral pneumonectomy in patients with severe ARDS.

5 Feb 2026

MET signaling plays a critical protective role in acetaminophen-induced acute liver failure

A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF).

2 Feb 2026

Eosinophils suppress tumor growth and recurrence in chordoma

Chordoma is a rare tumor characterized by poor prognosis, limited therapeutic options, and a high rate of recurrence. Despite advances in oncology, effective treatments for chordoma remain limited.

31 Jan 2026

Research uncovers alternative inflammatory pathway in rheumatoid arthritis treatment

The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients.

30 Jan 2026

Teen girls who play organized sports show lower breast cancer risk biomarkers

This cross-sectional study of 191 adolescent girls found that ≥2 hours of organized recreational physical activity in the past week was associated with lower breast percent water content and reduced oxidative stress. These biomarkers are linked to breast cancer risk, although causality and long-term outcomes cannot be inferred.

19 Jan 2026

"Super-probiotic" bacteria created through ribosomal engineering

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis mechanism of probiotic Lacticaseibacillus rhamnosus GG (LGG).

8 Jan 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Using contrast-enhanced ultrasound to distinguish hepatic PEComa from HCC without high-risk factors

Announcing a new article publication for BIO Integration journal. Hepatic perivascular epithelioid cell tumor (PEComa) is a rare tumor with malignant potential that is frequently misdiagnosed as hepatocellular carcinoma (HCC), despite requiring distinct treatment approaches.

6 Jan 2026

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

This review synthesizes evidence that gut microbiota dysbiosis contributes to insulin resistance and symptom severity in polycystic ovary syndrome through impaired barrier function, inflammation, and altered microbial metabolites. It evaluates how Traditional Chinese Medicine may modulate these pathways while highlighting major gaps in clinical validation, safety, and standardization.

16 Dec 2025

Hydrogel-based treatment achieves innervation and pulp-dentin regeneration

The dental pulp is susceptible to microbial infection, which often results in inflammation, necrosis, and defects in the pulp-dentin complex. Traditional treatment strategies suffer from multiple limitations and do not promote neural regeneration.

16 Dec 2025

Scientists map how cinnamon’s bioactives interact with cancer signaling

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.

15 Dec 2025

New findings show why the human intestine uniquely presents gluten to T cells

Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity and specialized machinery for processing gluten. Their ability to deamidate and present gliadin peptides positions them as key initiators of immune responses relevant to coeliac disease.

11 Dec 2025

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers profiled a terminally sterilized probiotic-fermented MFH beverage and identified aporphine alkaloids and flavonoids with favorable predicted ADMET properties. Integrated network pharmacology, molecular docking, and 100-ns MD simulations suggest multi-target engagement of metabolic-inflammatory pathways relevant to obesity and type 2 diabetes.

9 Dec 2025

Necrosis News and Research

Artificial lung keeps patient alive after lung removal

MET signaling plays a critical protective role in acetaminophen-induced acute liver failure

Eosinophils suppress tumor growth and recurrence in chordoma

Research uncovers alternative inflammatory pathway in rheumatoid arthritis treatment

Teen girls who play organized sports show lower breast cancer risk biomarkers

"Super-probiotic" bacteria created through ribosomal engineering

A single immune protein may help explain why kidney and heart disease often develop together

Using contrast-enhanced ultrasound to distinguish hepatic PEComa from HCC without high-risk factors

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

Hydrogel-based treatment achieves innervation and pulp-dentin regeneration

Scientists map how cinnamon’s bioactives interact with cancer signaling

New findings show why the human intestine uniquely presents gluten to T cells

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

AI method could help clinicians accurately identify brain tumors and radiation necrosis

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Sweat testing could transform drug monitoring and diabetes care

Ultrasound can aid in treating vascular occlusion events from cosmetic filler injections

Lack of dietary iron weakens immune response in the lungs

Innate immunity and metabolic stress drive a unique form of cell death

Tattoo ink alters immune cells and weakens some vaccine responses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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