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Triple therapy shows strong response in BRAF V600E mutant metastatic colorectal cancer

Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The University of Texas MD Anderson Cancer Center.

26 Jan 2025

Researchers investigate myocarditis in preschoolers caused by parvovirus B19 outbreak

Researchers document the harmful consequences of myocarditis in preschool students, caused by a regional outbreak of parvovirus B19 in northern Greece.

17 Jan 2025

Study reveals high prevalence of Lyme disease bacteria in Northeast ticks

Across most of the Northeast, getting bitten by a blacklegged tick- also called a deer tick - is a risk during spring, summer, and fall. A new Dartmouth study, published in Parasites and Vectors, finds that 50% of adult blacklegged ticks carry the bacteria that causes Lyme disease while 20% to 25% of the younger (nymph) blacklegged ticks carry the bacteria.

17 Jan 2025

Measles risk heightened by undernutrition in vulnerable children

Amid a global surge in measles cases, new research suggests that undernutrition may be exacerbating outbreaks in areas suffering from food insecurity.

16 Jan 2025

Parvovirus B19 myocarditis cases reported in preschoolers from Northern Greece

Myocarditis is a rare yet serious condition known for the inflammation of the heart muscle, also known as the myocardium. In severe cases of myocarditis, the heart muscle becomes extremely weak and fails to pump blood effectively.

9 Jan 2025

Australian study warns of growing drug resistance in canine hookworms

Canine hookworms are becoming increasingly resistant to drugs across Australia, according to new research.

6 Jan 2025

Antibody trials show encouraging results in patients with high-risk forms of two blood cancers

Two clinical trials testing the antibody loncastuximab tesirine (Zynlonta) showed encouraging results in patients with high-risk forms of two blood cancers – follicular lymphoma and marginal zone lymphoma.

9 Dec 2024

Chikungunya's health and economic impact likely underestimated

This study assesses chikungunya's health and economic impacts, revealing significant burdens on health systems and a global cost of approximately $49.9 billion.

5 Dec 2024

Advanced modeling unveils hidden costs of global chikungunya infection

The health and financial implications of the emerging threat of mosquito-borne chikungunya viral infection have most likely been significantly underestimated, with total costs probably approaching US$ 50 billion in 2011-20 alone, suggests a comprehensive data analysis, published in the open access journal BMJ Global Health.

4 Dec 2024

Update on diagnosis, risk classification and treatment of Kawasaki Disease

Advances in cardiac imaging techniques and risk categorization have led to improvements in diagnosis, initial treatment and long-term management of patients with Kawasaki Disease, according to a new scientific statement published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

14 Nov 2024

Dentists are pulling ‘healthy’ and treatable teeth to profit from implants, experts warn

Becky Carroll was missing a few teeth, and others were stained or crooked. Ashamed, she smiled with lips pressed closed. Her dentist offered to fix most of her teeth with root canals and crowns, Carroll said, but she was wary of traveling a long road of dental work.

1 Nov 2024

African production of mpox vaccines could secure the continent’s health

As Africa grapples with multiple outbreaks of mpox, public health leaders say locally produced vaccines are vital to end donation dependence and secure the continent's health.

29 Oct 2024

Scurvy may be making a comeback amid economic strain

The scourge of scurvy, which is caused by vitamin C deficiency, may be re-emerging amid the cost of living crisis and the rise in weight loss (bariatric) surgery, suggest doctors in the journal BMJ Case Reports after treating a middle-aged man with the condition.

22 Oct 2024

Long-term low-dose antiviral treatment reduces eye disease risk from shingles

Long-term, low-dose antiviral treatment reduces the risk for potentially vision-damaging bouts of inflammation and infection, as well as pain, which occur when shingles affects the eye, according to new research presented October 19 at the annual meeting of the American Academy of Ophthalmology (AAO) in Chicago.

20 Oct 2024

New combination treatment authorized for unresectable urothelial cancer patients

Astellas Pharma Ltd. today announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted authorization for PADCEV™ (enfortumab vedotin, an antibody-drug conjugate [ADC]) in combination with KEYTRUDA® (pembrolizumab, a PD-1 inhibitor) for the first-line treatment of adult patients with unresectable or metastatic urothelial cancer, who are eligible for platinum-containing chemotherapy.

18 Oct 2024

A review of clinical features, diagnosis, and management of Mpox

A comprehensive review in JAMA outlines monkeypox's clinical presentation and management, stressing the need for increased surveillance and vaccination efforts.

17 Oct 2024

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

16 Oct 2024

New insights into pain mechanisms related to viral infections

An article published in the journal Brain, Behavior, and Immunity reports the findings of a study by researchers based in Brazil, the United States and South Korea who set out to understand how viral infections cause pain and to contribute to the search for novel ways of relieving it.

15 Oct 2024

Study warns of increasing Rocky Mountain spotted fever cases among children in California

Recent cases of Rocky Mountain spotted fever in children underscore the effectiveness of mcf-NGS for early detection and timely treatment in non-endemic areas.