Structural Biology News and Research

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New algorithm enhances prediction of disordered protein structures

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging.

7 Mar 2025

New drug candidate may help combat metabolic dysfunction-associated steatotic liver disease

A study published in Nature Aging has revealed a promising new drug candidate that may help combat metabolic dysfunction-associated steatotic liver disease (MASLD), a chronic liver condition that disproportionately affects communities in San Antonio due to high rates of obesity and diabetes.

5 Mar 2025

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and their implications in various diseases.

5 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Study identifies key role of JMJD1C in acute myeloid leukemia

Acute myeloid leukemia (AML) is one of the most aggressive and genetically complex cancers, marked by the unchecked growth of immature myeloid cells.

3 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Skin organoids show promise for treating frostbite injuries

Frostbite is a severe cold injury that affects millions worldwide, often resulting in prolonged recovery, scarring, and long-term complications such as chronic pain and dysfunction.

3 Mar 2025

EU project aims to combat dangerous viruses with molecular interventions

Targeted molecular interventions in the replication cycle and the immune recognition of viruses are intended to prevent viral entry into cells and virus replication.

27 Feb 2025

Study explains why tecovirimat fails against some mpox strains

A virus originally found in animals, mpox – which causes the disease of the same name – is now circulating in humans.

13 Feb 2025

Collagen's structural diversity may be greater than previously believed, study suggests

Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues.

7 Feb 2025

New approach uses peptides to enhance anti-tumor drug formulations

A team of scientists has developed a groundbreaking approach using specially designed peptides to improve drug formulations.

24 Jan 2025

New compound V-161 offers hope in the fight against antibiotic-resistant bacteria

V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly reduces bacterial growth and colonization.

23 Jan 2025

Breakthrough study maps critical structure of Nipah virus polymerase

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.

20 Jan 2025

Researchers identify key mechanism linking brain stress to Alzheimer's disease

Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD).

23 Dec 2024

Breakthrough in understanding influenza's protective coat opens path to new treatments

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of eight RNA molecules.

17 Dec 2024

47th annual San Antonio Breast Cancer Symposium kicks off in December

Mays Cancer Center at The University of Texas Health Science Center at San Antonio (UT Health San Antonio), in partnership with the American Association for Cancer Research (AACR), is hosting the 47th annual San Antonio Breast Cancer Symposium at the Henry B. Gonzalez Convention Center on Dec. 10-13.

9 Dec 2024

Structural Biology News and Research

New algorithm enhances prediction of disordered protein structures

New drug candidate may help combat metabolic dysfunction-associated steatotic liver disease

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Study identifies key role of JMJD1C in acute myeloid leukemia

Stress granules as potential biomarkers for neurodegenerative diseases

Skin organoids show promise for treating frostbite injuries

EU project aims to combat dangerous viruses with molecular interventions

Study explains why tecovirimat fails against some mpox strains

Collagen's structural diversity may be greater than previously believed, study suggests

New approach uses peptides to enhance anti-tumor drug formulations

New compound V-161 offers hope in the fight against antibiotic-resistant bacteria

Breakthrough study maps critical structure of Nipah virus polymerase

Researchers identify key mechanism linking brain stress to Alzheimer's disease

Breakthrough in understanding influenza's protective coat opens path to new treatments

47th annual San Antonio Breast Cancer Symposium kicks off in December

Argonne receives $21.7 million to advance cancer and vaccine discoveries

Utilizing process Raman in optimizing cultivated meat production

Scientists uncover a previously unrecognized tumor suppression mechanism

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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