Antidepressant News and Research

RSS

Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

New treatment model of psychotherapy now listed on SAMHSA's national registry

A new treatment model of psychodynamic psychotherapy pioneered at Upstate Medical University for symptoms of borderline personality disorder, depression, heavy drinking, suicide attempts and self-harm behaviors is now listed on the Substance Abuse and Mental Health Services Administration (SAMHSA) National Registry of Evidence-based Practices and Programs.

25 May 2012

Most depressed patients must make multiple attempts before finding an effective antidepressant

UT Southwestern Medical Center psychiatrists are leading a national clinical trial to find biomarkers that can better predict how people suffering from depression will respond to medications so physicians eventually can personalize treatments.

16 May 2012

Delayed loss of nerve cells in the brain linked to symptoms of depression following stroke

Several weeks after mild brain ischemia, mice display a depressive-like syndrome characterized by increased anxiety, inactivity and "cheerlessness". These symptoms of depression following a stroke are associated with the delayed loss of nerve cells in the brain's reward regions. This is the major finding of a study published in the current issue of Biological Psychiatry.

16 May 2012

Non-drug therapy with NeuroStar TMS improves depression symptoms and QOL

New data released today at the annual meeting of the American Psychiatric Association show that patients with unipolar, non-psychotic Major Depressive Disorder (MDD) receiving transcranial magnetic stimulation (TMS) with NeuroStar TMS Therapy achieved significant improvements in both depression symptoms and in quality of life measurements.

9 May 2012

Results reported for clinical trial for the treatment of depression using external trigeminal nerve stimulation

Earlier today, at the American Psychiatric Association Annual Meeting in Philadelphia, Dr. Ian Cook, Principal Investigator and Professor of Psychiatry at UCLA, and a Senior Medical Advisor to NeuroSigma, Inc., presented the results of a Phase Ib open-label clinical trial that studied the effects of eTNS™ on depressive symptoms in Major Depressive Disorder (MDD) as an adjunct to pharmacotherapy. Results from the 17-question Hamilton Depression Rating Scale (HDRS-17), a clinician-rated scale, showed a 50.0% reduction in depression and the Beck Depression Inventory (BDI), a self-reported scale, showed a 58.0% reduction in scores. Both scales achieved statistical significance. In the trial, subjects placed stimulating eTNS™ electrodes on their foreheads for 8 hours each night and their depression was measured every two weeks using recognized standard tests. eTNS was well tolerated and no serious adverse events occurred during the 8-week treatment period.

9 May 2012

Two studies suggest long-term value of Deplin in treating MDD

Two studies presented this week at the 164th Annual Meeting of the American Psychiatric Association suggest the long-term value of Deplin (L-methylfolate 15mg) in treating major depressive disorder (MDD) and describe subsets of patients who may benefit more robustly from this medical food.

9 May 2012

eTNS therapy can impact symptoms in pharmacoresistant major depression

9 May 2012

Everett Labs announces availability of Pregnitude for women with fertility problems

A new non-prescription Reproductive Support Dietary Supplement, Pregnitude, which contains myo-inositol (2 g), plus folic acid (200 mcg), is now available for women who are having difficulty conceiving, Everett Laboratories announced today. In clinical studies, Pregnitude has been shown to help support ovulation function and menstrual cycle regularity as well as support the quality of a woman's eggs.

8 May 2012

Otsuka announces results from aripiprazole Phase 3 trial on schizophrenia

Otsuka Pharmaceutical Co., Ltd. and H. Lundbeck A/S today announced results from a Phase 3 clinical trial evaluating the efficacy, safety and tolerability of once-monthly aripiprazole intramuscular (IM) depot formulation for the maintenance treatment of adults with schizophrenia.

8 May 2012

Health Canada announces labelling update for Cipralex

Health Canada is informing Canadians of a labelling update for the prescription drug Cipralex (the brand name of the drug escitalopram) regarding a dose-related risk of abnormal heart rhythms. Cipralex is used to treat depression and belongs to a family of drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs).

7 May 2012

African-Americans with HIV less likely to adhere to ART therapy

African-Americans with HIV are much less likely to adhere to drug therapy than others with the disease, according to a University of Michigan study.

3 May 2012

Self-degradation response to antidepressant Zoloft observed in yeast cells

Princeton University researchers have observed a self-degradation response to the antidepressant Zoloft in yeast cells that could help provide new answers to lingering questions among scientists about how antidepressants work, as well as support the idea that depression is not solely linked to the neurotransmitter serotonin.

25 Apr 2012

Autism symptoms treatment using antidepressant SSRIs may not be effective: Review

According to a new review of published and unpublished research, the belief that certain antidepressants can help to treat repetitive behaviors in kids with autism may be based on incomplete information.

24 Apr 2012

HDAC6 protein may provide novel target for stress-linked disorders

A cellular protein called HDAC6, newly characterized as a gatekeeper of steroid biology in the brain, may provide a novel target for treating and preventing stress-linked disorders, such as depression and post-traumatic stress disorder (PTSD), according to research from the Perelman School of Medicine at the University of Pennsylvania.

24 Apr 2012

Study supports tolerability of low-dose aripiprazole as an antidepressant therapy-augmenting agent

In the current issue of Psychotherapy and Psychosomatics there is a negative study on the use of aripiprazole in depression.

18 Apr 2012

Newer antidepressant decreases depression in Parkinson's patients without worsening motor problems

Certain antidepressants appear to decrease depression in people with Parkinson's disease without worsening motor problems, according to a study published in the April 11, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Apr 2012

Pelvic floor muscle training effective for adult women with urinary incontinence

A type of exercise called pelvic floor muscle training is effective for treating adult women with urinary incontinence (the involuntary loss of urine) without risk of side effects, according to a new report from the U.S. Department of Health and Human Services' (HHS) Agency for Healthcare Research and Quality (AHRQ). The report also found that drug-based treatments can be effective, but the degree of benefit is low and side effects are common.

11 Apr 2012

Oxytocin may offer hope for male sexual dysfunction

The hormone oxytocin that is also called the “love hormone” since it plays a role in the bond between a mother and baby may also improve sexual function - at least in men with Asperger’s syndrome - according to a published case report.

10 Apr 2012

Poultry producers still use FDA-banned antibiotics

In a joint study, researchers at the Johns Hopkins Bloomberg School of Public Health and Arizona State University found evidence suggesting that a class of antibiotics previously banned by the U.S. government for poultry production is still in use. Results of the study were published March 21 in Environmental Science & Technology.

6 Apr 2012

Tonix completes TNX-102 pharmacokinetic study on fibromyalgia syndrome

Tonix Pharmaceuticals Holding Corp., a specialty pharmaceutical company developing therapies for challenging disorders of the central nervous system completed a pharmacokinetic (PK) study of the first formulation of its lead drug, TNX-102, for the treatment of fibromyalgia syndrome.

6 Apr 2012

Antidepressant News and Research

Further Reading

New treatment model of psychotherapy now listed on SAMHSA's national registry

Most depressed patients must make multiple attempts before finding an effective antidepressant

Delayed loss of nerve cells in the brain linked to symptoms of depression following stroke

Non-drug therapy with NeuroStar TMS improves depression symptoms and QOL

Results reported for clinical trial for the treatment of depression using external trigeminal nerve stimulation

Two studies suggest long-term value of Deplin in treating MDD

eTNS therapy can impact symptoms in pharmacoresistant major depression

Everett Labs announces availability of Pregnitude for women with fertility problems

Otsuka announces results from aripiprazole Phase 3 trial on schizophrenia

Health Canada announces labelling update for Cipralex

African-Americans with HIV less likely to adhere to ART therapy

Self-degradation response to antidepressant Zoloft observed in yeast cells

Autism symptoms treatment using antidepressant SSRIs may not be effective: Review

HDAC6 protein may provide novel target for stress-linked disorders

Study supports tolerability of low-dose aripiprazole as an antidepressant therapy-augmenting agent

Newer antidepressant decreases depression in Parkinson's patients without worsening motor problems

Pelvic floor muscle training effective for adult women with urinary incontinence

Oxytocin may offer hope for male sexual dysfunction

Poultry producers still use FDA-banned antibiotics

Tonix completes TNX-102 pharmacokinetic study on fibromyalgia syndrome

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News