Immune System News and Research

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Combination immunotherapy prior to surgery shows encouraging results in mesothelioma

Results from an early phase clinical trial presented this week at the World Conference on Lung Cancer Meeting in Barcelona, Spain, and published in the Nature Medicine journal today [Monday, 8th September 2025] show that patients with mesothelioma - a rare cancer of the lining of the lung that may be caused by exposure to asbestos - who received a combination of two immunotherapy drugs, nivolumab and ipilimumab, before surgery had successful surgeries and encouraging early outcomes.

9 Sep 2025

Dengue infection leaves lasting genetic imprint on immunity

Just as a computer's operating system can be rewritten after a major update, dengue infection can 're-programme' the body's immune system, leaving a long-lasting genetic imprint that influences how people respond to future infections-an effect not seen with vaccination.

9 Sep 2025

Cancer cells found to use ketones as alternate fuel for growth

When it comes to their survival, cancer cells have a host of backup plans.

8 Sep 2025

Scientists identify key protein driving severe flu in older people

Scientists have discovered why older people are more likely to suffer severely from the flu, and can now use their findings to address this risk.

8 Sep 2025

New hydrogel may help alleviate negative impacts of menopause

A new hydrogel applied directly to vaginal tissues may help alleviate the negative impacts of menopause, according to a new study from scientists at the University of California San Diego.

8 Sep 2025

How breast milk changes from day to night and why timing matters

Breast milk's hormonal and microbial variations throughout the day may affect infant development, emphasizing the need for synchronized feeding practices.

8 Sep 2025

New drug candidate STF 1623 activates innate immunity in solid tumors

Cancer immunotherapy, which primes the body's immune system to fight off tumors, has historically focused on harnessing T cells' natural ability to recognize and attack cancer cells.

5 Sep 2025

Piezo1 identified as key trigger for tension driven skin expansion

Investigators at Johns Hopkins Medicine report new evidence that the protein Piezo1 controls skin growth by detecting when skin is stretched and then coordinating the metabolic and immune changes necessary for growth.

5 Sep 2025

WHO expands essential medicines lists with new cancer and diabetes treatments

Today, the World Health Organization (WHO) has released updated editions of its Model Lists of Essential Medicines (EML) and Essential Medicines for Children (EMLc), adding new treatments for various types of cancer and for diabetes with associated comorbidities such as obesity.

5 Sep 2025

Targeting metabolic reprogramming to overcome immune suppression in head and neck cancer

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year.

5 Sep 2025

New insights into how breast milk supports baby’s internal clock

Breast milk is the first 'super food' for many babies. Full of vitamins, minerals, and other bioactive compounds, it helps build the young immune system and is widely considered the optimal source of infant nutrition.

5 Sep 2025

Understanding how mRNA stability influences immune diseases

A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas - if their cars don't break down on the way.

5 Sep 2025

Targeting ADAR1 offers new hope against glioblastoma

The most common and aggressive type of adult brain cancer, glioblastoma multiforme (GBM) is notoriously resistant to treatment, with a median survival of just 14 months following diagnosis.

5 Sep 2025

Research reveals how neutrophils orchestrate the mobilization of zinc to fight microbes

A research team from Umeå University, Sweden, in collaboration with Ghent University, Belgium, has made a groundbreaking discovery about how the body's first immune defense, neutrophils, orchestrate the mobilization of zinc to fight microbes.

5 Sep 2025

Gene expression maps explain why diseases often occur together

This study reveals how gene expression patterns uncover molecular pathways linking comorbidities, enhancing treatment strategies for overlapping diseases.

5 Sep 2025

First FDA-approved islet transplant at UI Health ends insulin dependence

Doctors at UI Health performed the first islet transplant with Lantidra, the only therapy approved by the U.S. Food and Drug Administration to treat brittle type 1 diabetes.

4 Sep 2025

Spaceflight accelerates aging of human blood stem cells

Researchers from University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), which are vital for blood and immune system health.

4 Sep 2025

Auburn researchers uncover staph’s superglue-like grip on human skin

Imagine a child with eczema who scratches a patch of irritated skin. A tiny opening forms, invisible to the eye.

4 Sep 2025

Breakthrough technology enables faster and cheaper antibody analysis

Antibodies are the critical targeting agents of the immune system and the crux of immune therapy and vaccine development, but studying them is slow, expensive and labor-intensive.

4 Sep 2025