Efficacy News and Research

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Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team from Weill Cornell Medicine and the University of Arizona Health Sciences has shown in new research.

10 Oct 2017

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.

9 Oct 2017

GW researchers receive NIH award to bring Zika vaccine trial to Brazil

The National Institute of Allergy and Infectious Disease of the National Institutes of Health awarded more than $2 million to a research team at the George Washington University School of Medicine and Health Sciences to facilitate a Zika vaccine trial in Brazil.

9 Oct 2017

University of Akron researcher awarded NSF grant to study bone remodeling

Osteoporosis is a disease categorized by brittle bones and increased risk of fracture. Individuals with osteoporosis, and diseases like it, have access to a number of treatments but no permanent solution.

9 Oct 2017

New studies provide insight into treatments for Barrett's esophagus

The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE). Two of these studies are highlighted below. BE is a condition in which there are unusual changes to the cells lining the esophagus. It is believed to be most commonly due to inflammation from gastroesophageal reflux disease (GERD).

6 Oct 2017

New antifungal drug developed to help in treatment of invasive fungal infections

University of Liverpool researchers, working with F2G Limited (Eccles, Manchester), have developed a new antifungal drug to help in the treatment of life threatening invasive fungal infections such as invasive aspergillosis.

6 Oct 2017

New webinar highlights importance of data integrity in GxP-regulated laboratories

As regulators continue to tighten their inspection approaches, it is critical for managers and scientists in regulated laboratories to understand the key issues surrounding data integrity and be able to demonstrate compliance.

6 Oct 2017

New cell therapy restores movement in people with paralyzing spinal cord injuries

Four of six people with paralyzing spinal cord injuries who were treated with a new cell therapy have recovered two or more motor levels on at least one side, new study results show.

6 Oct 2017

Are expensive cancer drugs being approved without enough proof that they work?

Recent research indicates that only half of the cancer drugs approved by the European Medicines Agency (EMA) showed benefit in patients.

6 Oct 2017

Good-guy bacteria may help individuals respond well to cancer immunotherapy

Individuals with certain types of bacteria in their gut may be more likely to respond well to cancer immunotherapy, researchers at the Harold C. Simmons Comprehensive Cancer Center found in a study of patients with metastatic melanoma.

5 Oct 2017

JAX professor receives $2.8 million New Innovator Award for skin microbiome research

Julia Oh, Ph.D., a Jackson Laboratory (JAX) assistant professor who explores the communities of microorganisms that live on the human skin, has received a special New Innovator Award of $2,835,000 from the National Institutes of Health (NIH) to explore how to develop engineered probiotic treatments for a variety of skin and infectious diseases.

5 Oct 2017

Next-generation CPR training device launched on Kickstarter to educate users during cardiac arrests

South Korean-based healthcare product Development Company I.M. Lab has launched its next-generation CPR training aide "cprCUBE" on Kickstarter. The device will educate the user about 'proper' mechanism of chest compression during cardiac arrests with better efficiency compared to the dated and pricey CPR training with patient-mannequins.

5 Oct 2017

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans, according to new research from the Perelman School of Medicine at the University of Pennsylvania, conducted in partnership with The Wistar Institute, Inovio Pharmaceuticals, and GeneOne Life Science, Inc.

5 Oct 2017

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

In a recent clinical trial, a gene therapy to treat cerebral adrenoleukodystrophy (CALD) -- a neurodegenerative disease that typically claims young boys' lives within 10 years of diagnosis -- effectively stabilized the disease's progression in 88 percent of patients, researchers from the Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Massachusetts General Hospital report today.

4 Oct 2017

Researchers awarded NIH grant to develop, test new drugs for treating Giardia infections

The microscopic parasite Giardia can be found within Idaho, every region of the U.S. and around the world. While Giardia is not considered fatal, anyone who has suffered from the diarrheal disease knows how uncomfortable it can be.

3 Oct 2017

Researchers look for ways to prevent chemotherapy-induced cognitive impairment

Of the 14 million cancer survivors in the United States, a significant number experience a serious side effect called chemotherapy-induced cognitive impairment (CICI). While easily recognized, little is known about the etiology of this condition, also known informally as "chemo brain."

3 Oct 2017

New gene therapy to treat cancer in children, young adults offers hopes and challenges

The first gene therapy for cancer, approved by the Food Drug Administration in August, will transform the treatment of a particular kind of cancer in children and young adults. It's transformative because it uses a patient's own immune cells to attack the cancer cells.

3 Oct 2017

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Historically, randomized controlled trials have served as the state-of-the-art method for determining the efficacy and safety of new, innovative treatment regimens for patients with cancer and other diseases.

28 Sep 2017

Clinical trial demonstrates safety, efficacy of focused ultrasound to treat pediatric osteoid osteoma

Karun Sharma, MD, PhD, Director of Interventional Radiology, and colleagues at Sheikh Zayed Institute for Pediatric Surgical Innovation at Children's National Health System in Washington, DC, have completed their clinical trial to treat benign but painful bone tumors (osteoid osteoma) in children.

27 Sep 2017

FAU neuroscientist develops innovative program to prevent dementia

More than 5 million Americans today are affected by Alzheimer's disease (AD). If nothing is done to stop this upward trajectory, there will be more than 16 million people with AD in the United States and more than 60 million people with AD worldwide by 2050.

27 Sep 2017

Efficacy News and Research

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

GW researchers receive NIH award to bring Zika vaccine trial to Brazil

University of Akron researcher awarded NSF grant to study bone remodeling

New studies provide insight into treatments for Barrett's esophagus

New antifungal drug developed to help in treatment of invasive fungal infections

New webinar highlights importance of data integrity in GxP-regulated laboratories

New cell therapy restores movement in people with paralyzing spinal cord injuries

Are expensive cancer drugs being approved without enough proof that they work?

Good-guy bacteria may help individuals respond well to cancer immunotherapy

JAX professor receives $2.8 million New Innovator Award for skin microbiome research

Next-generation CPR training device launched on Kickstarter to educate users during cardiac arrests

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

Researchers awarded NIH grant to develop, test new drugs for treating Giardia infections

Researchers look for ways to prevent chemotherapy-induced cognitive impairment

New gene therapy to treat cancer in children, young adults offers hopes and challenges

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Clinical trial demonstrates safety, efficacy of focused ultrasound to treat pediatric osteoid osteoma

FAU neuroscientist develops innovative program to prevent dementia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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