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New LEAP technique can restore heart rhythm in patients with atrial fibrillation

A high-amplitude, and often painful, electrical shock is the only currently available method for treating certain cases of chronic cardiac arrhythmia. But now a new technique using much weaker impulses has been developed by an international team of physicists and cardiologists, including Alain Pumir, CNRS researcher at the ENS Lyon physics laboratory.

28 Jul 2011

FDA accepts peginesatide NDA for anemia associated with CKD

Affymax, Inc. and Takeda Global Research & Development Center, Inc., U.S., today announced that the U.S. Food and Drug Administration (FDA) accepted for review the New Drug Application (NDA) for peginesatide (formerly known as Hematide™) for the treatment of anemia associated with chronic kidney disease (CKD) in adult patients on dialysis.

27 Jul 2011

Underwater-treadmill improves mobility following spinal-cord injury

The result of research often is shown in hard and fast metrics. For Janette Rodgers, the only metric she cares about is that her wheelchair, once her prison day in and day out, now sits empty 90 percent of the time— in large part because of the hours she spent in 270 gallons of water.

27 Jul 2011

Positive results from phase Ib/IIa trial of novel molecular technique for Duchenne muscular dystrophy

A molecular technique originally developed at the University of North Carolina at Chapel Hill has taken one step closer to becoming a treatment for the devastating genetic disease Duchenne muscular dystrophy.

27 Jul 2011

High-dose vitamin D reduces musculoskeletal pain in breast cancer patients

High-dose vitamin D relieves joint and muscle pain for many breast cancer patients taking estrogen-lowering drugs, according to a new study from Washington University School of Medicine in St. Louis.

27 Jul 2011

New preclinical data suggests microRNA-15 inhibits cardiomyogenesis

miRagen Therapeutics, Inc., a biopharmaceutical company focused on improving patients' lives by developing innovative microRNA (miRNA)-based therapeutics for cardiovascular and muscle disease, announced today that new preclinical data published in the online edition of Circulation Research suggests that microRNA-15 (miR-15) inhibits cardiomyogenesis, the process whereby new heart muscle cells are formed.

27 Jul 2011

Positive data from two GSK's Promacta Phase III studies on hepatitis C-related thrombocytopenia

Ligand Pharmaceuticals Incorporated today announced that its partner GlaxoSmithKline has announced that it received positive data from ENABLE-1, the first of two Phase III studies examining Promacta in patients with hepatitis C-related thrombocytopenia, and that full data will be released at an upcoming scientific conference.

27 Jul 2011

Health Canada issues notice of compliance for OCPI's SAMSCA to treat hyponatremia

Otsuka Canada Pharmaceutical Inc. (OCPI) announced today that Health Canada has issued a notice of compliance for SAMSCA (tolvaptan), the first medicine approved in Canada for the treatment of hyponatremia.

27 Jul 2011

Key risk factors for death, transplantation in children with dilated cardiomyopathy

Researchers have identified important risk factors for death and transplantation in children with dilated cardiomyopathy, according to results from a study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

26 Jul 2011

Symposium papers highlight role of oxidative stress in cardiovascular disease

Recent years have seen major advances in understanding of the health effects of oxidative stress—including its potential to cause injury to the cardiovascular system. A series of expert updates on the role of oxidative stress in heart failure, atherosclerosis, and other cardiovascular diseases appears in a special symposium in the August issue of The American Journal of the Medical Sciences, official journal of the Southern Society for Clinical Investigation.

26 Jul 2011

New hope for infants born with Spinal Muscular Atrophy

Researchers in Ottawa report new hope for the treatment of infants born with serious genetic disorder.

26 Jul 2011

Fragile X syndrome study to reveal more

Fragile X syndrome is the most common inherited cause of intellectual disability in the world. Medical experts, including the Mater Hospital's Dr Helen Heussler, are today launching a new push to uncover the secrets of a disorder that affects a child born in Australia every week. Fragile X is passed from parent carriers who often exhibit very few symptoms. Estimates suggest more than 100,000 Australians either carry the gene mutation that causes Fragile X or have the syndrome, yet the vast majority have not been diagnosed, according to the Fragile X Association of Australia.

25 Jul 2011

Promising drug for Duchenne muscular dystrophy

Duchenne muscular dystrophy is a severely debilitating and lethal condition that affects 1 in 3,000. Females and males are affected, though females are rarely affected and are more often carriers. It is caused due to a defective gene that normally codes for the protein dystrophin, which helps provide a protective membrane around muscle fibers. Without this skin, muscle fibers become damaged and eventually die.

25 Jul 2011

Illinois Bone and Joint Institute upgrades to High Field Open MRI System

Illinois Bone and Joint Institute, MRI Services, is proud to announce the installation of the first High Field Open MRI serving patients of Chicago and Northeastern Illinois.

25 Jul 2011

Janssen receives FDA Complete Response letter for SIMPONI sBLA to treat RA

Janssen Biotech, Inc. announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response letter for its supplemental Biologics License Application (sBLA) for SIMPONI.

25 Jul 2011

Rats, fish oil and beetroot juice could lead to health breakthroughs for aging populations

Though rats, fish oil and beetroot juice read like ingredients in a witch's brew, to a Kansas State University research team, information from this combination could lead to health breakthroughs for aging populations and people suffering from heart failure and diabetes.

22 Jul 2011

Elite task force provides insights and guidance on deep brain stimulation for dystonia

Neurologist Michele Tagliati, MD, director of the Movement Disorders Program at Cedars-Sinai Medical Center, served on an elite international task force commissioned by the Movement Disorder Society to provide insights and guidance on deep brain stimulation for dystonia, an uncommon condition that causes sustained, sometimes crippling muscle contractions.

22 Jul 2011

Scientists directly link lipid metabolism and cancer-associated cachexia

Scientists from Graz, Austria, have now directly linked lipid metabolism and cancer-associated cachexia. Science reports via its online channel Science Express that mice deficient in the lipid degrading enzyme Adipose Triglyceride Lipase (ATGL) are fully protected against cancer-associated cachexia.

22 Jul 2011

UCSF neurosurgery shows promise against severe epilepsy

Two-thirds of people with severe and otherwise untreatable epilepsy were completely cured of their frequent seizures after undergoing neurosurgery at the University of California, San Francisco Medical Center, according to a new study that examined 143 of these patients two years after their operations.

22 Jul 2011

FDA approves Merz Aesthetics' XEOMIN for temporary improvement of glabellar lines

Merz Aesthetics today announced that the United States (U.S.) Food and Drug Administration (FDA) has approved XEOMIN for the temporary improvement in the appearance of moderate to severe glabellar lines, or frown lines between the eyebrows, in adult patients.

22 Jul 2011

Muscle News and Research

New LEAP technique can restore heart rhythm in patients with atrial fibrillation

FDA accepts peginesatide NDA for anemia associated with CKD

Underwater-treadmill improves mobility following spinal-cord injury

Positive results from phase Ib/IIa trial of novel molecular technique for Duchenne muscular dystrophy

High-dose vitamin D reduces musculoskeletal pain in breast cancer patients

New preclinical data suggests microRNA-15 inhibits cardiomyogenesis

Positive data from two GSK's Promacta Phase III studies on hepatitis C-related thrombocytopenia

Health Canada issues notice of compliance for OCPI's SAMSCA to treat hyponatremia

Key risk factors for death, transplantation in children with dilated cardiomyopathy

Symposium papers highlight role of oxidative stress in cardiovascular disease

New hope for infants born with Spinal Muscular Atrophy

Fragile X syndrome study to reveal more

Promising drug for Duchenne muscular dystrophy

Illinois Bone and Joint Institute upgrades to High Field Open MRI System

Janssen receives FDA Complete Response letter for SIMPONI sBLA to treat RA

Rats, fish oil and beetroot juice could lead to health breakthroughs for aging populations

Elite task force provides insights and guidance on deep brain stimulation for dystonia

Scientists directly link lipid metabolism and cancer-associated cachexia

UCSF neurosurgery shows promise against severe epilepsy

FDA approves Merz Aesthetics' XEOMIN for temporary improvement of glabellar lines

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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