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Naloxone can save lives but stigma is preventing its use among newly abstinent opioid users

Opioids are the main driver of fatal drug overdoses in the United States, according to the Centers for Disease Control and Prevention, resulting in 46,802 deaths in 2018, usually because the person stops breathing.

26 Mar 2021

Study shows how migrating cells interact in the body

By offering a microscopic "tightrope" to cells, Virginia Tech and Johns Hopkins University researchers have brought new insights to the way migrating cells interact in the body.

26 Mar 2021

Antibody used for COVID-19 therapy does not inhibit SARS-Cov-2 variants

Cell culture studies show that mutated viruses are less susceptible to inhibition by antibodies from recovered or vaccinated individuals.

26 Mar 2021

New technology to obtain 'protein fingerprints' in just a few minutes

Researchers from Charité - Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes.

25 Mar 2021

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center has been awarded two research grants totaling $6 million from the National Institutes of Health to identify new ways to treat pancreatic cancer.

25 Mar 2021

Study shows persisting cognitive benefits of common Alzheimer’s treatment

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer's disease, but their effects on cognition have been debated and few studies have investigated their long-term effects.

25 Mar 2021

FDA approves new indication for drug to treat pediatric NDO patients

Today, the U.S. Food and Drug Administration approved a new indication for Myrbetriq (mirabegron extended-release tablets) and Myrbetriq Granules (mirabegron for extended-release oral suspension) to treat neurogenic detrusor overactivity (NDO), a bladder dysfunction related to neurological impairment, in children ages three years and older.

25 Mar 2021

KHN’s ‘What the Health?’: Getting down to work at HHS

As questions swirl about the Covid vaccine made by AstraZeneca, public health experts are worried the confusion could create more doubts among people already hesitant to get a vaccine.

25 Mar 2021

Drugging RNA synthesis in SARS-CoV-2 as novel therapeutic avenue

In a new study, the role of a coronavirus-specific protein domain in SARS-CoV-2 viral synthesis initiation is investigated, and potential therapeutic solutions have been explored.

25 Mar 2021

Study observes correlation between COVID-19 mortality and autoantibodies in corticosteroid treated patients

Corticosteroid anti-inflammatory drugs have been applied to COVID-19 patients over the course of the pandemic, though the results are mixed. In a recent study, the outcomes for such patients are collated, demonstrating a striking correlation between the development of autoantibodies and mortality.

25 Mar 2021

New machine learning algorithm ranks drugs based on efficacy in reducing cancer cell growth

Researchers from the Queen Mary University of London have developed a machine learning algorithm that ranks drugs based on their efficacy in reducing cancer cell growth.

25 Mar 2021

Researchers examine SARS-CoV-2 RNA interactome

A new study focuses on the identification of RNA-binding protein by mass spectrometry (ChIRP-M/S) approach. This study develops a global map that contains the complete set of host proteins that involve the SARS-CoV-2 genome during infection. This study has successfully identified new SARS-CoV-2 host dependency factors by merging proteomics data with gene silencing experiments. Such a discovery has paved new roads to develop more antiviral therapies.

25 Mar 2021

Researcher to use new approach to explore brain proteins and their potential to cure mental diseases

Dr. Hans Maric has received one of the German Research Foundation's highly prestigious Emmy Noether awards, worth around 1.7 million euros.

25 Mar 2021

Fluoxetine (Prozac) performs strongly in vitro against SARS-CoV-2 (including mutants)

Researchers from Finland, to expand on these studies, tested some of these drugs against the new SARS-CoV-2 variants. The study is published on the preprint server bioRxiv.

24 Mar 2021

‘COVID-19 fears’ prevent many Africans from accessing malaria treatment

Fears of contracting COVID-19 are preventing people accessing vital health services, experts say.

24 Mar 2021

Repurposed heart and flu drugs that protect platelets improve survival of septic mice

Despite continued improvements in antibiotics and hospital intensive care, staph sepsis - a bloodstream infection caused by Staphylococcus aureus bacteria - still causes severe illness or death in 20 to 30 percent of patients who contract it.

24 Mar 2021

New compound may provide a basis for drug development against COVID-19

SARS-CoV-2, the virus responsible for the COVID-19 pandemic, arrived one year ago and turned our lives upside-down.

24 Mar 2021

Three commonly used antiviral drugs potentially effective at preventing replication of SARS-CoV-2

An international team of researchers has found that three commonly used antiviral and antimalarial drugs are effective in vitro at preventing replication of SARS-CoV-2, the virus that causes COVID-19.

24 Mar 2021

Research could lead to a personalized approach for treating sickle cell disease

Sickle cell disease is the most prevalent inherited blood disorder in the world, affecting 70,000 to 100,000 Americans. However, it is considered an orphan disease, meaning it impacts less than 200,000 people nationally, and is therefore underrepresented in therapeutic research.

24 Mar 2021

Researchers examine acriflavine's antiviral potential against SARS-CoV-2

Acriflavine is traditionally employed as a topical antiseptic, though has more recently been implicated as an antiviral agent at low doses, potentially by stimulating the production of interferon. In a new study recently uploaded to the bioRxiv* preprint server, the application of the drug to SARS-CoV-2 infection is investigated, demonstrating a broad activity towards a range of other betacoronaviruses.

24 Mar 2021

Drugs News and Research

Naloxone can save lives but stigma is preventing its use among newly abstinent opioid users

Study shows how migrating cells interact in the body

Antibody used for COVID-19 therapy does not inhibit SARS-Cov-2 variants

New technology to obtain 'protein fingerprints' in just a few minutes

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

Study shows persisting cognitive benefits of common Alzheimer’s treatment

FDA approves new indication for drug to treat pediatric NDO patients

KHN’s ‘What the Health?’: Getting down to work at HHS

Drugging RNA synthesis in SARS-CoV-2 as novel therapeutic avenue

Study observes correlation between COVID-19 mortality and autoantibodies in corticosteroid treated patients

New machine learning algorithm ranks drugs based on efficacy in reducing cancer cell growth

Researchers examine SARS-CoV-2 RNA interactome

Researcher to use new approach to explore brain proteins and their potential to cure mental diseases

Fluoxetine (Prozac) performs strongly in vitro against SARS-CoV-2 (including mutants)

‘COVID-19 fears’ prevent many Africans from accessing malaria treatment

Repurposed heart and flu drugs that protect platelets improve survival of septic mice

New compound may provide a basis for drug development against COVID-19

Three commonly used antiviral drugs potentially effective at preventing replication of SARS-CoV-2

Research could lead to a personalized approach for treating sickle cell disease

Researchers examine acriflavine's antiviral potential against SARS-CoV-2

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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