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New shingles vaccine gets FDA panel votes

On the 13th of September 2017, a U.S. Food and Drug Administration (FDA) advisory panel has voted 11 to 0 approving a shingles vaccine for its use in adults aged 50 and over. The panel unanimously accepted the safety and efficacy of the vaccine and thus GlaxoSmithKline’s Shingrix is on its way to FDA approval.

14 Sep 2017

Novel technology holds promise for improving accuracy of type 1 diabetes tests

Researchers from the Johns Hopkins University School of Medicine, Stanford University and the University of Florida report the development of a novel antibody detection technology that holds promise for improving the accuracy of diagnostic tests for type 1 diabetes in young children and making populationwide screening practical.

13 Sep 2017

Combination immunotherapy shows better overall survival in kidney cancer patients

A combination immunotherapy treatment showed better overall survival in patients with previously untreated advanced or metastatic renal cell carcinoma than current therapy, according to results from a phase 3 clinical trial presented at the Presidential Symposium of the European Society for Medical Oncology's 2017 Congress in Spain.

13 Sep 2017

Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes.

13 Sep 2017

MGH researchers identify potential strategy for improving efficacy of angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a potential strategy for improving the efficacy of angiogenesis inhibitors, drugs that help fight cancer by blocking the formation of new blood vessels.

13 Sep 2017

Insmed reports top-line data from Phase 3 study of new treatment in patients with NTM lung disease

Insmed Incorporated, a global biopharmaceutical company focused on the unmet needs of patients with rare diseases, today announced top-line data from its Phase 3 CONVERT study.

13 Sep 2017

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

Study adds more evidence that racial, socioeconomic disparities may occur during surgical pain management

A "look back" analysis of more than 600 major colorectal surgeries using a "checklist" tool has added further evidence that racial and socioeconomic disparities may occur during many specific stages of surgical care, particularly in pain management.

13 Sep 2017

Study finds potential preventive for chemotherapy-induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy, or CIPN, is a common side effect of cancer treatment that causes shooting or burning pain, numbness, tingling and cold sensitivity of the hands and feet for many cancer patients.

13 Sep 2017

Young men have lowest risk of relapse after antireflux surgery, study finds

Surgery for severe heartburn has become less common after the turn of the millennium, due in part to the fear of relapse.

12 Sep 2017

$New medication shows potential to reduce fracture risk in women with osteoporosis$

New medication shows potential to reduce fracture risk in women with osteoporosis

A new drug that boosts bone formation has been shown to reduce the risk of fracture in women with osteoporosis when compared to one of the most commonly used osteoporosis medications.

12 Sep 2017

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

An antibody treatment reduces the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant chronic obstructive pulmonary disease (COPD), according to the results of two large international trials presented today at the European Respiratory Society International Congress in Milan, Italy, and simultaneously published in the New England Journal of Medicine.

12 Sep 2017

Tracking eye movements offers new method for monitoring temporal expectation in ADHD

A technique that measures tiny movements of the eyes may help scientists better understand and perhaps eventually improve assessment of ADHD, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

12 Sep 2017

Study findings may have critical implications to boost efficacy of T cell-based therapies

T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy.

11 Sep 2017

Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Combination immunotherapy as second or third line treatment extends overall survival to at least 15 months in patients with pleural malignant mesothelioma, according to late-breaking results from the MAPS2 trial presented today at the ESMO 2017 Congress in Madrid.

11 Sep 2017

Meningitis B vaccine’s high price tag poses a health care conundrum

Four years ago, when meningitis B, an extremely rare but potentially lethal form of the infection, sickened a small number of college students at Princeton and the University of California-Santa Barbara, there was no vaccine against the disease sold in the U.S. Despite its availability abroad, it had never been licensed in the country due to its limited marketability.

8 Sep 2017

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Pembrolizumab has shown a promising response rate in patients with pretreated metastatic gastric cancer, according to late-breaking results from the KEYNOTE-059 trial presented today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

The superiority of docetaxel based triplet therapy over standard care in patients with resectable oesophago-gastric cancer has been confirmed in late-breaking results from the FLOT4 trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Internet-based IRT may be effective treatment to improve nightmare distress

Nightmares are extremely dysphoric dreams, which are prevalent and associated with psychological strain. This study investigated (a) the efficacy of an internet-based imagery rehearsal therapy (IRT), (b) the role of imagery rescription, and (c) the role of guidance during internet-based IRT.

8 Sep 2017

Self-help preventive cognitive therapy found to be effective in reducing recurrent depression

In the current issue of Psychotherapy and Psychosomatic a Group of Dutch investigators reports on the findings of a randomized controlled trial on the role of self-help in depression.

8 Sep 2017

Efficacy News and Research

New shingles vaccine gets FDA panel votes

Novel technology holds promise for improving accuracy of type 1 diabetes tests

Combination immunotherapy shows better overall survival in kidney cancer patients

Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

MGH researchers identify potential strategy for improving efficacy of angiogenesis inhibitors

Insmed reports top-line data from Phase 3 study of new treatment in patients with NTM lung disease

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

Study adds more evidence that racial, socioeconomic disparities may occur during surgical pain management

Study finds potential preventive for chemotherapy-induced peripheral neuropathy

Young men have lowest risk of relapse after antireflux surgery, study finds

New medication shows potential to reduce fracture risk in women with osteoporosis

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

Tracking eye movements offers new method for monitoring temporal expectation in ADHD

Study findings may have critical implications to boost efficacy of T cell-based therapies

Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Meningitis B vaccine’s high price tag poses a health care conundrum

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

Internet-based IRT may be effective treatment to improve nightmare distress

Self-help preventive cognitive therapy found to be effective in reducing recurrent depression

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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