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Direct-acting antiviral therapy found to be safe, effective in patients with CKD and HCV infection

A new study indicates that direct-acting antiviral therapy is safe and effective in patients with chronic kidney disease (CKD) and Hepatitis C virus (HCV) infection.

8 Sep 2017

Study describes link between key melanoma signaling pathway and novel class of drugs

Results of a study by The Wistar Institute have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful information for a more effective use of this type of treatment.

7 Sep 2017

Study finds long-term effectiveness of HPV vaccine in preventing cervical cancer

A vaccine that can literally eradicate the majority of cervical cancer cases shows long-term effectiveness in a study published today in The Lancet.

6 Sep 2017

Ketogenic diet prolongs life and improves memory and physical functions in aged mice find researchers

A pair of new studies find that diets termed ketogenic that are classically low in carbohydrates can prolong life in adult male laboratory mice. In addition this ketogenic diet also preserves the memory functions as well as muscle masses of the aged mice that were fed on it. The mechanism behind this could be the fact that ketogenic diet induces protein acetylation in the mice liver and muscles.

5 Sep 2017

High levels of suPAR protein shown to be likely cause of kidney damage in children

High levels of a protein known as suPAR, which has been shown to be a marker and likely cause of kidney damage, is as reliably predictive in children as in adults, according to results of a study published online today in JAMA Pediatrics, a clinical publication of the American Medical Association.

5 Sep 2017

Study: Neurofeedback holds potential to treat people suffering from treatment-resistant depression

A small pilot study has indicated that neurofeedback - where patients concentrate on modifying their own brainwave patterns - has potential to treat many of the 100m people worldwide who suffer from Treatment-Resistant Depression (TRD).

4 Sep 2017

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

The U.S. Food and Drug Administration today approved Mylotarg (gemtuzumab ozogamicin) for the treatment of adults with newly diagnosed acute myeloid leukemia whose tumors express the CD33 antigen (CD33-positive AML).

1 Sep 2017

Pfizer receives FDA approval for new therapy to treat adults and children with AML

Pfizer Inc. today announced that the U.S. Food and Drug Administration approved MYLOTARG (gemtuzumab ozogamicin) for adults with newly diagnosed CD33-positive acute myeloid leukemia (AML), and adults and children 2 years and older with relapsed or refractory CD33-positive AML.

1 Sep 2017

Researchers reveal therapeutic benefits of melatonin for treating blood cancers

Researchers have examined the potential benefits of melatonin, a hormone made by a small gland in the brain, for treating blood cancers such as leukemia and lymphoma.

1 Sep 2017

New crowdfunding campaign aims to develop, test novel photographic biomarkers of aging in mice

The Biogerontology Research Foundation announces the launch of a crowdfunding campaign, MouseAge, to develop and test photographic biomarkers of ageing in mice in collaboration with scientists from Harvard University, University of Oxford, Youth Laboratories and Insilico Medicine.

31 Aug 2017

Study finds transcranial direct-current stimulation to be less effective than anti-depressants

A new study questions the efficacy of treatments for depression based on stimulating brain areas with low-intensity electric current. The technique, known as transcranial direct-current stimulation (tDCS), was considered a promising alternative to treatment with antidepressant drugs.

31 Aug 2017

Children likely to experience post-traumatic stress post-hurricane Harvey

As flood waters recede, families along the Gulf Coast need to watch for post-traumatic stress among children and adolescents, says a Virginia Tech expert in trauma psychology in the areas of natural and technological disasters.

31 Aug 2017

Beta blockers capable of reducing stress signaling may enhance effectiveness of immunotherapy

While the development of therapies designed to block "checkpoints" within the immune system has been one of the most exciting and noteworthy advances in cancer research in recent years, it's also been one of the most puzzling, leaving researchers to ask: Why don't these new therapies work for more patients, and why is their efficacy in controlling cancerous tumors often short-lived? A research team from Roswell Park Cancer Institute has shown that at least one answer - and an excellent opportunity for unleashing the full potential of these promising immunotherapies - may lie in the body's "fight or flight" reaction to stressors and in drugs already widely used to control and temporarily disable this stress response.

31 Aug 2017

New method of genetic testing leads to successful targeting of MET fusion in lung cancer

There are many ways a gene can be altered and there are many genes that, when altered, can cause cancer. Testing individually for each possible alteration in every cancer-related gene is not feasible as it would require hundreds of individual tests and many, many thousands of dollars.

31 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

FDA approves new antibacterial treatment for adults with cUTI

The U.S. Food and Drug Administration today approved Vabomere for adults with complicated urinary tract infections (cUTI), including a type of kidney infection, pyelonephritis, caused by specific bacteria. Vabomere is a drug containing meropenem, an antibacterial, and vaborbactam, which inhibits certain types of resistance mechanisms used by bacteria.

30 Aug 2017

FDA grants accelerated approval to new treatment for children with Chagas disease

The U.S. Food and Drug Administration today granted accelerated approval to benznidazole for use in children ages 2 to 12 years old with Chagas disease. It is the first treatment approved in the United States for the treatment of Chagas disease.

29 Aug 2017

Excluding children from school may lead to long- term psychiatric problems, study shows

Excluding children from school may lead to long- term psychiatric problems and psychological distress, a study of thousands of children has shown.

29 Aug 2017

Efficacy News and Research

Direct-acting antiviral therapy found to be safe, effective in patients with CKD and HCV infection

Study describes link between key melanoma signaling pathway and novel class of drugs

Study finds long-term effectiveness of HPV vaccine in preventing cervical cancer

Ketogenic diet prolongs life and improves memory and physical functions in aged mice find researchers

High levels of suPAR protein shown to be likely cause of kidney damage in children

Study: Neurofeedback holds potential to treat people suffering from treatment-resistant depression

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

Pfizer receives FDA approval for new therapy to treat adults and children with AML

Researchers reveal therapeutic benefits of melatonin for treating blood cancers

New crowdfunding campaign aims to develop, test novel photographic biomarkers of aging in mice

Study finds transcranial direct-current stimulation to be less effective than anti-depressants

Children likely to experience post-traumatic stress post-hurricane Harvey

Beta blockers capable of reducing stress signaling may enhance effectiveness of immunotherapy

New method of genetic testing leads to successful targeting of MET fusion in lung cancer

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

FDA approves first cell-based gene therapy for use in the United States

FDA approves new antibacterial treatment for adults with cUTI

FDA grants accelerated approval to new treatment for children with Chagas disease

Excluding children from school may lead to long- term psychiatric problems, study shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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