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CLEOPATRA Phase III study on HER2-positive mBC meets primary endpoint

Genentech, a member of the Roche Group, today announced that CLEOPATRA, a pivotal Phase III study, met its primary endpoint.

15 Jul 2011

BK channel activation involves structural rearrangements: Study

BK channels are essential for the regulation of important biological processes such as smooth muscle tone and neuronal excitability. New research shows that BK channel activation involves structural rearrangements formerly not understood.

15 Jul 2011

NeoStem to acquire Amorcyte

NeoStem, Inc., an international biopharmaceutical company, announced the signing of a definitive merger agreement whereby NeoStem will acquire Amorcyte, Inc., a development stage cell therapy company focusing on novel treatments for cardiovascular disease.

15 Jul 2011

Study examines teaching hospitals' so-called 'July Effect'

A new study reports that more patients receive worse-quality care or die at teaching hospitals during July because experienced residents shuffle off to greener pastures, leaving untrained "newbies" to take their spots and learn the ropes.

14 Jul 2011

New low-energy method for terminating cardiac fibrillation

An international team of scientists from the Max-Planck-Institute for Dynamics and Self-Organization, Cornell University the Ecole Normale Supérieure de Lyon, the University Medicine Göttingen, the Rochester Institute of Technology, and the Institut Non-Linéaire de Nice have developed a new low-energy method for terminating life-threatening cardiac fibrillation of the heart.

14 Jul 2011

New less painful technique to end life-threatening heart fibrillations

Cornell scientists, in collaboration with physicists and physician-scientists in Germany, France and Rochester, N.Y., have developed a new - and much less painful and potentially damaging - method to end life-threatening heart fibrillations.

14 Jul 2011

UW scientists determine atomic architecture of sodium channel

Scientists at the University of Washington (UW) in Seattle have determined the atomic architecture of a sodium channel. The achievement opens new possibilities for molecular medicine researchers around the world in designing better drugs for pain, epilepsy, and heart rhythm disturbances.

14 Jul 2011

Bladder cancer patients rarely receive recommended care: Study

According to a study released this week by UCLA's Jonsson Comprehensive Cancer Center, the overwhelming majority of patients with high-grade non-muscle invasive bladder cancer do not receive the recommended treatment and surveillance, leaving them at higher risk for bladder cancer recurrence, progression, and death.

13 Jul 2011

Bladder cancer patients missing out on treatment and followups: Study

A new study released this Monday by UCLA's Jonsson Comprehensive Cancer Center shows a large majority of patients with high-grade non-muscle invasive bladder cancer do not receive the recommended treatment and surveillance, leaving them at higher risk for bladder cancer recurrence, progression, and death.

13 Jul 2011

Researchers identify biomarker for familial risk of autism

Siblings of people with autism show a similar pattern of brain activity to that seen in people with autism when looking at emotional facial expressions. The University of Cambridge researchers identified the reduced activity in a part of the brain associated with empathy and argue it may be a 'biomarker' for a familial risk of autism.

13 Jul 2011

Ivermectin cream demonstrates activity against head lice eggs

In a study sponsored by Topaz Pharmaceuticals Inc., a privately held specialty pharmaceutical company, scientists from the University of Massachusetts, Amherst presented data showing that a 0.5% ivermectin (IVM) cream formulation was active against lice eggs from permethrin resistant head lice.

11 Jul 2011

Scientists study neuronal excitation to treat neurological disorders

Oh, the challenges of being a neuron, responsible for essential things like muscle contraction, gland secretion and sensitivity to touch, sound and light, yet constantly bombarded with signals from here, there and everywhere.

11 Jul 2011

Vitamin D insufficiency may increase risk of muscle injuries in NFL football players

Vitamin D deficiency has been known to cause an assortment of health problems, a recent study being presented at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in San Diego today, suggests that lack of the vitamin might also increase the chance of muscle injuries in athletes, specifically NFL football players.

11 Jul 2011

MicroOCT technology can reveal cellular features of coronary artery disease

Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) have developed a one-micrometer-resolution version of the intravascular imaging technology optical coherence tomography (OCT) that can reveal cellular and subcellular features of coronary artery disease.

11 Jul 2011

Dietary protein reduces hunger and increases fullness in obese men

A new study demonstrates that higher-protein meals improve perceived appetite and satiety in overweight and obese men during weight loss. According to the research, published in Obesity, higher-protein intake led to greater satiety throughout the day as well as reductions in both late-night and morning appetite compared to a normal protein diet.

11 Jul 2011

Body builders using greyhound injections to increase muscle mass

According to reports many body builders are injecting drugs meant for greyhounds in the mistaken belief it will help them build bigger muscles faster. L-carnitine is found in supplements sold for human consumption but these users are buying an injectable form from pet shops which experts say can increase the risk of heart attacks. L-carnitine is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.

10 Jul 2011

Mesenchymal stem cells protect and heal

A stem cell that can morph into a number of different tissues is proving a natural protector, healer and antibiotic maker, researchers at Case Western Reserve University and their peers have found.

8 Jul 2011

Novartis Afinitor Phase III trial on tuberous sclerosis meets primary endpoint

Novartis Pharmaceuticals Corporation announced today Phase III trial results that showed more than one-third of patients taking Afinitor tablets experienced a 50% or greater reduction in the size of their subependymal giant cell astrocytomas, non-cancerous brain tumors associated with tuberous sclerosis complex.

8 Jul 2011

Experiment to protect astronauts from bone loss during space travel

Astronauts lose a significant amount of bone mass during space travel and with long duration flights there is concern that this bone loss could lead to an increased risk of fractures.

7 Jul 2011

Loyola to launch interdisciplinary Geriatric Fracture Program

Loyola University Hospital is launching an interdisciplinary Geriatric Fracture Program to reduce hospital stays and complications from broken hips and other age-related fractures.

7 Jul 2011