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Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

The United States Food and Drugs Administration FDA has granted permission for phase 3 trials in PTSD (Post traumatic stress disorder) patients using Ecstasy and psychotherapy in a treatment protocol called MDMA-Assisted Psychotherapy PTSD affects thousands of war veterans and other individuals and often leads to fatal outcomes of self-harm and suicides

28 Aug 2017

Study: Left atrial appendage closure during open heart surgery protects against brain infarctions

Closure of the left atrial appendage during heart surgery protects the brain, according to late-breaking research presented today in a Hot Line LBCT Session at ESC Congress. The results suggest that closure should be routinely added to open heart surgery.

28 Aug 2017

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Concurrent administration of the T-cell stimulating anti-OX40 antibody and the immune checkpoint inhibitor anti-PD1 antibody attenuated the effect of anti-OX40 and resulted in poor treatment outcomes in mice.

28 Aug 2017

Studies reveal strategies for using shingles vaccine in arthritis patients

New research indicates that the live varicella-zoster vaccine--which is given to protect against shingles--elicits robust immune responses in patients when administered several weeks prior to the start of treatment with the arthritis drug tofacitinib.

28 Aug 2017

SLU-led project receives NIH funding for clinical trial on potential treatment for MDR-TB

Saint Louis University is leading a multi-national clinical trial of what could become a regimen for drug resistant tuberculosis (TB) that does not require injectable medications. The project is funded by a $6.4 million task order from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

26 Aug 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

Astex celebrates as breast cancer drug gets European marketing approval

Astex Pharmaceuticals, a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics for oncology and diseases of the central nervous system, announced today that its long-standing pharmaceutical collaborator, Novartis, has received marketing approval in Europe for Kisqali (ribociclib) plus an aromatase inhibitor as a first-line treatment in post-menopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) locally advanced or metastatic breast cancer.

26 Aug 2017

NIH grant for CWRU professors could enable new directions for cancer immunotherapies

Nicole Steinmetz, PhD, Associate Professor of Biomedical Engineering, Radiology, member of the Case Comprehensive Cancer Center and the Center for RNA Science and Therapeutics in the Division of General Medical Sciences at Case Western Reserve University School of Medicine and the holder of the George J. Picha Designated Professor in Biomaterials, has received a major grant from the National Institutes of Health to help understand how a virus-like particle from plants stimulates potent anti-tumor responses.

26 Aug 2017

Benefits of charcoal-based dentifrices for oral hygiene still unproven

The growing visibility of charcoal and charcoal-based dentifrices, including many that are offered for sale on the Internet, raises questions about the re-emerging practice of brushing teeth with products containing charcoal.

24 Aug 2017

New research aims to generate in vitro vascularized pancreatic islets from hPSCs

Tiny packets of cells called islets throughout the pancreas allow the organ to produce insulin. Type 1 diabetes -- also known as juvenile diabetes - tricks the immune system into destroying these islets.

23 Aug 2017

CBT approaches found to be effective and efficient in treating ADHD symptoms in adults

Cognitive-behavioral therapy (CBT) group training was shown to achieve the same results as neurofeedback training in treating attention-deficit hyperactivity disorder (ADHD). Both methods led to a comparable decrease in symptoms.

23 Aug 2017

New blood test can predict drug resistance in patients with advanced prostate cancer

When bacteria develop antibiotic resistance, treatment with these medications becomes ineffective. Similarly, tumor cells can also change in such a way that renders them resistant to particular medications.

22 Aug 2017

Sex-until-after-marriage programs in the United States have been ineffective study shows

Two research papers have been released that show that the abstinence-only-until-marriage (AOUM) programs and policies in the United States are ineffective by and large and have not been successful in reducing risky sexual behaviors or early initiation of sex. Studies have reported that these are programs that successfully withhold medically accurate information not to mention infringe on adolescent human rights and reinforce gender stereotypes. The findings are published in the Journal of Adolescent Health.

22 Aug 2017

Gut-on-chips can predict effectiveness of candidate drugs

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

22 Aug 2017

New vaccine could offer protection against opioid combinations

Substance abuse is a continuing problem in the U.S., particularly with heroin and other opioids, to the point of being an epidemic.

21 Aug 2017

New technique quickly, economically monitors multiple molecular interactions in living tissues

A new approach to optical imaging makes it possible to quickly and economically monitor multiple molecular interactions in a large area of living tissue -- such as an organ or a small animal; technology that could have applications in medical diagnosis, guided surgery, or pre-clinical drug testing.

18 Aug 2017

Efficacy News and Research

Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

Study: Left atrial appendage closure during open heart surgery protects against brain infarctions

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Studies reveal strategies for using shingles vaccine in arthritis patients

SLU-led project receives NIH funding for clinical trial on potential treatment for MDR-TB

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

Astex celebrates as breast cancer drug gets European marketing approval

NIH grant for CWRU professors could enable new directions for cancer immunotherapies

Benefits of charcoal-based dentifrices for oral hygiene still unproven

New research aims to generate in vitro vascularized pancreatic islets from hPSCs

CBT approaches found to be effective and efficient in treating ADHD symptoms in adults

New blood test can predict drug resistance in patients with advanced prostate cancer

Sex-until-after-marriage programs in the United States have been ineffective study shows

Gut-on-chips can predict effectiveness of candidate drugs

New vaccine could offer protection against opioid combinations

New technique quickly, economically monitors multiple molecular interactions in living tissues

Combination treatment effectively vaccinates mice against cancer

MR-guided focused ultrasound continues to gain momentum in treating essential tremor patients

Researchers rebut theory that antidepressants do not exert any actual effect

Drug blocked by regulators found to improve quality of life for MS patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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