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New machine learning technique could quicken the pace of drug discovery

Drugs can only work if they stick to their target proteins in the body. Assessing that stickiness is a key hurdle in the drug discovery and screening process. New research combining chemistry and machine learning could lower that hurdle.

15 Mar 2021

48Hour Discovery and Merck join hands to accelerate drug development

48Hour Discovery and CQDM are proud to announced that the company has been awarded $800,000 for peptide drug discovery using its patented drug discovery platform.

15 Mar 2021

Researchers find no evidence to suggest a link between beta blockers and depression

Drugs such as beta-adrenergic antagonists (beta blockers) have been linked to a range of adverse effects, including depression.

15 Mar 2021

Discovery may help cancer patients to avoid chemotherapy's debilitating side effects

A discovery by University of Queensland pain researchers may allow some future cancer patients, including children with leukemia, to avoid their chemotherapy's worst and most debilitating side effects.

15 Mar 2021

The role of nanotechnology in the fight against COVID-19

Appearing in the journal Nanomedicine, the review summarized all the exciting advances made using diverse nanomaterials (polymeric, inorganic self-assembling materials and peptide-based) towards COVID-19 prevention, diagnosis and therapy.

15 Mar 2021

WHA’s president outlines plans to improve treatments for patients with hepatitis

Danjuma Adda, a Nigerian public health expert, became the president-elect of the World Hepatitis Alliance (WHA) in November last year. He is the first African to hold the position.

15 Mar 2021

Soluble ACE2 level correlates with COVID-19 outcomes

Researchers at the Aarhus University, Denmark, found that high baseline levels of ACE2 in plasma from COVID-19 patients are tied to a worse outcome in hospitalized patients. The study, which appeared on the pre-print server medRxiv, shows that measuring ACE2 levels in serum can help determine patients at a higher risk of developing severe illness from SARS-CoV-2 infection.

14 Mar 2021

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

In a methodologically trailblazing paper published in the journal Nature Genetics, a team of Belgian scientists uncovered an assembly of coronavirus host factors that may be exploited to develop drugs against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also potentially forthcoming zoonotic coronaviruses.

14 Mar 2021

Less-educated, unmarried patients less likely to undergo a transplant for mantle cell lymphoma

Mantle cell lymphoma is a malignant disease in which intensive treatment can prolong life. In a new study, scientists from Uppsala University and other Swedish universities show that people with mantle cell lymphoma who were unmarried, and those who had low educational attainment, were less often treated with a stem-cell transplantation, which may result in poorer survival.

13 Mar 2021

Researchers discover new mechanism that contributes to airway hyperresponsiveness in asthma

In asthma, the airways become hyperresponsive. Researchers from Uppsala University have found a new mechanism that contributes to, and explains, airway hyperresponsiveness.

13 Mar 2021

Overexpression of signaling protein in heart associated with poor survival after heart attack

About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate - some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease, for which new therapies are desperately needed.

13 Mar 2021

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

In a study published in the journal Drugs, a researcher tackled the approval of Pfizer-BioNTech’s COVID-19 vaccine, which has now been used in many countries.

12 Mar 2021

Novel tool can add or remove sugar from proteins

Sugar has been called "evil," "toxic," and "poison." But the body needs sugars, too. Sugar molecules help cells recognize and fight viruses and bacteria, shuttle proteins from cell to cell, and make sure those proteins function.

12 Mar 2021

U.S. Congress has clear opportunity to supercharge global health R&D, shows report

The U.S. Congress and Biden-Harris administration have a clear opportunity to supercharge global health research and development (R&D) in the wake of a pandemic that has revealed both the sector's chronic neglect and amazing potential.

12 Mar 2021

Immune-modified ex vivo platform can measure treatment response of ovarian cancer

KIYATEC, Inc researchers demonstrated that their immune-modified ex vivo platform can measure treatment response through direct interaction between a patient's cancer and infiltrating immune cells, and immuno-oncology agents.

12 Mar 2021

New book provides general introduction about COVID-19, history, and diagnosis

Recently, a novel coronavirus (2019-nCoV) emerged in China and rapidly spread worldwide. It is declared an ongoing outbreak as a global public health emergency by the World Health Organization (WHO).

12 Mar 2021

New study sheds light on cancer metastasis

Breast cancer is harmful enough on its own, but when cancer cells start to metastasize -- or spread into the body from their original location -- the disease becomes even more fatal and difficult to treat.

12 Mar 2021

A new methodology to define and diagnose problematic video gaming

In 2019, the World Health Organization recognised Gaming disorder as a clinical condition, but the proposed diagnostic criteria and clinical guidelines remain the subject of an intense scientific debate.

12 Mar 2021

Princeton researchers elucidate how hepatitis B virus establishes chronic infection

Researchers at Princeton have determined how five cellular proteins contribute to an essential step in the life cycle of hepatitis B virus (HBV).

11 Mar 2021

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials

Henry Ford Cancer Institute is launching the Participatory Action for Access to Clinical Trials (PAACT) project to dramatically improve the representation of the African American community and other minorities in cancer clinical trials.

11 Mar 2021

Drugs News and Research

New machine learning technique could quicken the pace of drug discovery

48Hour Discovery and Merck join hands to accelerate drug development

Researchers find no evidence to suggest a link between beta blockers and depression

Discovery may help cancer patients to avoid chemotherapy's debilitating side effects

The role of nanotechnology in the fight against COVID-19

WHA’s president outlines plans to improve treatments for patients with hepatitis

Soluble ACE2 level correlates with COVID-19 outcomes

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

Less-educated, unmarried patients less likely to undergo a transplant for mantle cell lymphoma

Researchers discover new mechanism that contributes to airway hyperresponsiveness in asthma

Overexpression of signaling protein in heart associated with poor survival after heart attack

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

Novel tool can add or remove sugar from proteins

U.S. Congress has clear opportunity to supercharge global health R&D, shows report

Immune-modified ex vivo platform can measure treatment response of ovarian cancer

New book provides general introduction about COVID-19, history, and diagnosis

New study sheds light on cancer metastasis

A new methodology to define and diagnose problematic video gaming

Princeton researchers elucidate how hepatitis B virus establishes chronic infection

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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