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Antidepressant drug should have suicide warning for adults as well as children

According to a Norwegian study, adults taking the antidepressant drug paroxetine are at a higher risk of attempting to commit suicide than those not taking medication.

22 Aug 2005

Paroxetine linked to higher rate of suicide

Adult patients taking the antidepressant drug paroxetine are at higher risk of attempting to commit suicide than those not taking medication.

22 Aug 2005

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

For people with long-standing rheumatoid arthritis, combined treatment with the new "biologic" drug adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.

15 Aug 2005

Combined gene therapy eliminates glioblastoma multiforme in lab studies

Despite aggressive treatment, glioblastoma multiforme (GBM) - the most common and deadly of brain cancers - usually claims the lives of its victims within six to 12 months of diagnosis. Because GBM is so aggressive, the disease has been the target of a number of laboratory and clinical studies investigating the effectiveness of gene therapy to deliver novel therapies to the brain.

15 Aug 2005

Roflumilast could become a new therapeutic strategy for patients with chronic obstructive pulmonary disease

An anti-inflammatory drug called roflumilast could become a new therapeutic strategy for patients with chronic obstructive pulmonary disease (COPD), conclude the results of a randomised trial in this week’s issue of The Lancet.

11 Aug 2005

Alternative to Cox II inhibitors

After the failure of cox II inhibitors such as Vioxx, osteoarthritis patients and their doctors are faced with a lack of alternative therapies. The Orthokine-therapy means knee-injections of IL-1Ra protein, obtained from the patient's blood.

11 Aug 2005

Taking parathyroid hormone followed by a year on alendronate shows strong osteoporosis benefit

Postmenopausal women who took a bone-building drug for one year followed by a year on a standard drug that fights bone loss experienced greater increases in bone density than has been reported from any other drug regimen, an NIH-sponsored study has found. Bone density is the standard predictor of fracture risk associated with osteoporosis.

11 Aug 2005

$Experts predict that bone fractures will become a bigger and more costly problem$

Experts predict that bone fractures will become a bigger and more costly problem

With an aging population, and with people living longer, experts say bone fractures will become a bigger and more costly problem unless more is done to prevent them.

9 Aug 2005

Supplements of multivitamins and minerals don't prevent infections in the elderly

Researchers at the University of Aberdeen in Scotland, say giving daily supplements of multivitamins and minerals do not prevent respiratory, stomach, skin and other types of infections in the elderly.

8 Aug 2005

Switching treatment to the drug anastrozole after two years of tamoxifen is beneficial for women with early breast cancer

Switching treatment to the drug anastrozole after two years of tamoxifen can improve eventfree survival for postmenopausal women with early breast cancer, concludes a study in this week’s issue of The Lancet.

4 Aug 2005

Multivitamins don't prevent infections in older people

Multivitamin and mineral supplements don't appear to prevent infections in older people living at home, finds a study in this week's British Medical Journal (BMJ).

4 Aug 2005

MediciNova starts phase II clinical trial of MN-166 for multiple sclerosis

MediciNova today announced the enrollment of patients in a Phase II clinical study with MN-166 for the treatment of multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. MN-166 is an orally administered drug with a novel mechanism of action that includes the inhibition of phosphodiesterase IV.

2 Aug 2005

Acupuncture is an effective treatment for tension headache

And a minimal acupuncture course works almost as well as traditional Chinese therapy, say the researchers.

28 Jul 2005

Echinacea little use in relieving colds

According to a new study by the University of Virginia School of Medicine, taking the the herbal remedy Echinacea, to relieve the symptoms of the common cold, is a waste of time and offers no more relief than a placebo.

28 Jul 2005

First trial of pramipexole for the treatment of fibromyalgia

The mechanism of fibromyalgia, a chronic illness characterized by muscle pain, fatigue, and sleep disturbances, is unknown and medications used to treat it (such as antidepressants, antiepileptics, muscle relaxants, antiinflammatories, sedative hypnotics, pain relievers and nutriceuticals) have had limited success.

28 Jul 2005

Testosterone patch makes older women feel sexy

Women who experience a reduction in sexual desire after the surgical removal of the ovaries, can now be treated with a patch containing the hormone testosterone in order to increase sexual desire and activity.

27 Jul 2005

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Opiates appear to better "ameliorate the withdrawal, facilitate feeding and potentially reduce the likelihood of seizures," according to two new systematic reviews done by David Osborn, a neonatologist at the Royal Prince Alfred Hospital in Sydney, Australia, and colleagues.

26 Jul 2005

Potential new treatment for nerve damage caused by diabetes

Research into a new treatment for nerve damage caused by diabetes could bring relief to millions of diabetic patients, say experts.

From The University of Manchester 26 Jul 2005

Analysis of the Phase I/II clinical trial of HIV drug candidate PA-457

V.I. Technologies (Vitex) and collaborators at the University at Buffalo's School of Pharmacy and Pharmaceutical Sciences, Buffalo, NY, today presented a detailed analysis of the Phase I/II clinical trial of its HIV drug candidate PA-457 at the 3rd International AIDS Society (IAS) Conference on HIV Pathogenesis and Treatment in Rio de Janeiro, Brazil.

26 Jul 2005

Investigational vaccine against Clostridium difficile

Acambis has announced that earlier this month it started a Phase I clinical trial of its investigational vaccine against Clostridium difficile (C. difficile).

26 Jul 2005

Placebo News and Research

Antidepressant drug should have suicide warning for adults as well as children

Paroxetine linked to higher rate of suicide

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

Combined gene therapy eliminates glioblastoma multiforme in lab studies

Roflumilast could become a new therapeutic strategy for patients with chronic obstructive pulmonary disease

Alternative to Cox II inhibitors

Taking parathyroid hormone followed by a year on alendronate shows strong osteoporosis benefit

Experts predict that bone fractures will become a bigger and more costly problem

Supplements of multivitamins and minerals don't prevent infections in the elderly

Switching treatment to the drug anastrozole after two years of tamoxifen is beneficial for women with early breast cancer

Multivitamins don't prevent infections in older people

MediciNova starts phase II clinical trial of MN-166 for multiple sclerosis

Acupuncture is an effective treatment for tension headache

Echinacea little use in relieving colds

First trial of pramipexole for the treatment of fibromyalgia

Testosterone patch makes older women feel sexy

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Potential new treatment for nerve damage caused by diabetes

Analysis of the Phase I/II clinical trial of HIV drug candidate PA-457

Investigational vaccine against Clostridium difficile

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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