Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

Researchers evaluated the stability and expression of mutations in the spike protein of SARS-CoV-2.

24 Mar 2022

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Scientists from the United States have recently assessed the evolutionary success of mutations accumulated across severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. They have observed that the positively-selected mutations in the viral spike S1 subunit are primarily responsible for adaptive evolution. This indicates that the virus may undergo antigenic drift.

23 Mar 2022

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

There is likely recombination of genome sequences between the SARS-CoV-2 Delta and Omicron variants in their spike (S) protein.

23 Mar 2022

Genomic sequencing reveals unique pattern of SARS-CoV-2 Epsilon emergence in Alaska

Researchers used genomic sequencing to examine SARS-CoV-2 genomes from Alaska, United States, between December 2020 and June 2021.

23 Mar 2022

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Research published today in Nature Chemical Biology reveals new opportunities for using small molecule drugs to target KRAS, the most commonly mutated protein in cancer.

23 Mar 2022

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Researchers presented a systematic analysis of the affinity and conformational dynamics between the binding of SARS-CoV-2 receptor-binding domain spike protein and the host angiotensin-converting enzyme 2 receptor.

22 Mar 2022

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

In a recent study posted to the bioRxiv* preprint server, researchers conducted a phylogenetic investigation of the human parainfluenza type 3 virus strain (HPIV3) that caused an outbreak in South Korea amid the coronavirus disease 2019 (COVID-19) pandemic.

22 Mar 2022

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Researchers demonstrate the broad neutralization potential of a strategically engineered circRNA using mice as a model system.

21 Mar 2022

Researchers find effective nutritional strategies to prevent acute kidney injury

A research team led by Professor Dr Roman-Ulrich Müller has established that four out of six different nutritional strategies prevent acute kidney injury in the mouse model.

21 Mar 2022

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

In a new study, researchers investigated whether the SARS-CoV-2 spike protein and its S2 subunit induced the expression of C–X–C motif chemokine 10, a subset of cytokine.

21 Mar 2022

Multiple inter-variant recombination events identified in Omicron subvariants

Newly emerging and circulating Omicron subvariants have originated partially through recombination with other variants.

20 Mar 2022

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Researchers developed covalent nanobodies to neutralize severe acute respiratory syndrome coronavirus-2 and its variants.

18 Mar 2022

Study explores SARS-CoV-2 spike epitope with potent and broad neutralization

Researchers reported an epitope with high potency and breadth and demonstrated that a therapeutic antibody directed at this site neutralizes all SARS-CoV-2 variants.

18 Mar 2022

Researchers argue that Omicron's lower severity is a coincidence

Researchers raised concern regarding the emergence of new SARS-CoV-2 variants with unpredictable severity and immune evasion potential due to its ongoing fast-paced antigenic evolution.

18 Mar 2022

Novel screening method detects new N501T SARS-CoV-2 variant

Researchers develop two SARS-CoV-2 Mutation Discrimination assays that have been designed to detect 501 and 484 mutations on the spike protein.

17 Mar 2022

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Researchers constructed a novel fusion inhibitor−based recombinant protein, referred to as 5−Helix, to block SARS-CoV-2 spike-mediated cell-cell fusion.

17 Mar 2022

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases.

16 Mar 2022

Multisystem inflammatory syndrome as a late complication in COVID-19 infected children

Researchers determined the immune signature of the multisystem inflammatory syndrome in children among hospitalized children diagnosed with SARS‐CoV‐2 infection.

16 Mar 2022

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

Researchers identified curcumin derivatives as potential inhibitors of SARS-CoV-2 enzymes.

16 Mar 2022

Novel targets to inhibit SARS-CoV-2 variants

A new study identified additional targets on SARS-CoV-2 proteins to prevent the emergence of new SARS-CoV-2 variants of concern.

16 Mar 2022

Amino Acid News and Research

Further Reading

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

Genomic sequencing reveals unique pattern of SARS-CoV-2 Epsilon emergence in Alaska

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Researchers find effective nutritional strategies to prevent acute kidney injury

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

Multiple inter-variant recombination events identified in Omicron subvariants

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Study explores SARS-CoV-2 spike epitope with potent and broad neutralization

Researchers argue that Omicron's lower severity is a coincidence

Novel screening method detects new N501T SARS-CoV-2 variant

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

Multisystem inflammatory syndrome as a late complication in COVID-19 infected children

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

Novel targets to inhibit SARS-CoV-2 variants

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