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Ketamine's antidepressant effects involve the brain's opioid system

Ketamine is a highly effective, fast-acting antidepressant that works even for patients who have not responded to other medications.

24 Jul 2025

Ivermectin mass treatment shows great promise in reducing malaria transmission

Ivermectin administered to the whole population significantly reduces malaria transmission, offering new hope in the fight against the disease.

24 Jul 2025

Innovative immunotherapy trial opens for newly-diagnosed glioblastoma patients

A UCL-sponsored clinical trial for patients newly diagnosed with glioblastoma, an aggressive form of brain cancer, has opened at UCLH's National Hospital for Neurology and Neurosurgery and Clinical Research Facility, in memory of Baroness Margaret McDonagh.

24 Jul 2025

Weill Cornell Medicine launches study to advance treatments for rare neurological disorder

A $1.1 million grant from the parent-caregiver-led Rare Bird Foundation to Weill Cornell Medicine is supporting the launch of a natural history study for a rare neurodevelopmental disorder that causes developmental delays and seizures called MEF2C Haploinsufficiency syndrome (MCHS).

23 Jul 2025

Liupao tea improves metabolic syndrome risks in clinical trial

Liupao tea shows promise in improving metabolic syndrome markers, enhancing heart health and gut balance in just three months, according to recent research.

23 Jul 2025

Breakthrough gene therapy reverses genetic deafness across age groups

Using gene therapy to treat hereditary deafness is safe and effective in both children and adults, according to new findings from a multicenter clinical trial.

22 Jul 2025

Cannabis and psychedelics rated most effective for symptom relief by eating disorder patients

A pioneering international survey of people living with eating disorders has found that cannabis and psychedelics, such as 'magic mushrooms' or LSD, were best rated as alleviating symptoms by respondents who self-medicated with the non-prescribed drugs.

22 Jul 2025

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute.

22 Jul 2025

New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

Amid PFAS fallout, a Maine doctor navigates medical risks with her patients

When Lawrence and Penny Higgins of Fairfield, Maine, first learned in 2020 that high levels of toxic chemicals called PFAS taint their home's well water, they wondered how their health might suffer.

22 Jul 2025

Walking faster offers a simple solution to age-related frailty

Older adults who are prefrail or frail can increase their walking cadence through structured interventions, leading to significant gains in physical function. A rise in steps per minute was closely linked to meaningful improvements in walking endurance.

21 Jul 2025

Prime editing reverses symptoms of severe childhood neurological disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

21 Jul 2025

Combination of two cancer drugs could treat the most common form of dementia

A study comparing the gene expression signature of Alzheimer's disease with those elicited by 1,300 approved drugs found a combination of two cancer medications that could treat the most common form of dementia.

21 Jul 2025

Microbial therapy uses modified bacteria to target oxalate in the gut

Engineered gut bacteria designed to treat kidney stones successfully colonized the gut microbiome and reduced oxalate levels in animal models and early clinical trials in humans, researchers report.

18 Jul 2025

New mRNA vaccine strategy awakens immune system to fight cancer

An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.

18 Jul 2025

Heart failure and atrial fibrillation at the time of mitral valve repair linked to worse outcomes

Patients with heart failure and atrial fibrillation (AF) at the time of mitral transcatheter edge-to-edge repair (M-TEER) for severe mitral regurgitation are more than twice as likely to die or be rehospitalized for heart failure, compared to patients without AF.

18 Jul 2025