Mass Spectrometry News and Research

RSS

Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Researchers map first-ever proteome of healthy human heart

A healthy heart beats about two billion times during a lifetime – thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute of Biochemistry and the German Heart Centre at the Technical University of Munich have now determined which and how many individual proteins are present in each type of cell that occurs in the heart.

17 Nov 2017

New discovery may lead to natural products for preventing dental caries

A new discovery may one day lead to natural anticavity products, researchers report. The scientists from West China School of Stomatology and Academic Centre for Dentistry Amsterdam have figured out the main active ingredient of Galla Chinensis, a natural herb, and further improved its anti-caries efficacy. The finding is published in The Open Dentistry Journal.

16 Nov 2017

Researchers find low levels of neuroactive steroid in both obese and anorexic women

Women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, according to new research published in the journal Neuropsychopharmacology.

10 Nov 2017

Adipocytes may reduce effectiveness of chemotherapeutic drug

Adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes.

8 Nov 2017

Study reveals role of specific lipids in accelerating or curbing bacterial infection

Lipids appear to play an important role in infections. According to researchers from the University of Maastricht in Maastricht, The Netherlands, and the University of Maryland, Baltimore (UMB) in Baltimore, Md., USA, specific lipids can greatly accelerate bacterial infection.

7 Nov 2017

Review explains nuances of non-invasive prenatal screening for pregnant women

As the use of non-invasive prenatal screening (NIPS) grows, there has been concern within the medical community that a poor understanding of this technique among clinicians and patients could negatively impact pregnancies.

3 Nov 2017

Saliva proteins could explain differences in salt perception among people

Many Americans consume too much salt. Now in a study appearing in the Journal of Agricultural and Food Chemistry, scientists report that people who can easily taste salt have differing amounts of certain proteins in their saliva than those who are less sensitive.

2 Nov 2017

Dinosaur extinction metal can be used to kill cancer cells

Cancer cells can be targeted and destroyed with the metal from the asteroid that caused the extinction of the dinosaurs, according to new research by an international collaboration between the University of Warwick and Sun Yat-Sen University in China.

2 Nov 2017

Study demonstrates beneficial effects of calorie-restricted diet in mice

Caloric restriction diets have been associated with various health benefits, but their effects on the skin have not been previously demonstrated. Research conducted at the University of São Paulo (USP) in Brazil shows that controlling calories helps mice live longer, although it reduces the reserves of fat in adipose tissue needed to keep the body warm.

30 Oct 2017

Study: New histone modifications link cellular metabolism to chromatin architecture

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published in 'Nature Structural and Molecular Biology'.

26 Oct 2017

Mysterious DNA modification appears more in the brain under stress

With advances in genomics, scientists are discovering additional components of the DNA alphabet in animals. Do these unusual chemical modifications of DNA have a special meaning, or are they just signs that cellular machines are making mistakes?

24 Oct 2017

TSRI scientists develop molecular model for improving design of osteoporosis treatments

Using advanced mass spectrometry technology, scientists from the Florida campus of The Scripps Research Institute have developed a molecular model that may provide a new framework for improving the design of osteoporosis treatments.

13 Oct 2017

Human minibrains expose psychedelic drug effects, study reveals

A Brazilian study has detected variations in signaling pathways that are associated with neurodegeneration, inflammation, and neural plasticity stimulated by a compound from the dimethyltryptamine family known as 5-MeO-DMT.

10 Oct 2017

Study unveils neuronal effects of psychedelics using cerebral organoids

A Brazilian study, published in Scientific Reports on October 09, 2017, has identified changes in signaling pathways associated with neural plasticity, inflammation and neurodegeneration triggered by a compound from the family of dimethyltryptamine known as 5-MeO-DMT.

9 Oct 2017

Two MSU researchers team up to tackle problem of arsenic poisoning

Two Montana State University researchers in different disciplines have teamed up to tackle the problem of arsenic poisoning, which is estimated by the World Health Organization to affect more than 100 million people worldwide, primarily through tainted drinking water.

4 Oct 2017

Scientists develop rapid, highly sensitive fingerprint test to detect cocaine users

Scientists from the University of Surrey have developed a rapid and highly sensitive fingerprint test that can take just seconds to confirm whether someone has used cocaine.

22 Sep 2017

New solutions for autonomous LC-MS sample preparation introduced by Tecan

Tecan has unveiled its latest innovation, the automated RESOLVEX™ A200 positive pressure workstation for LC-MS sample prep.

20 Sep 2017

Analytical Science in Precision Medicine

Pittcon is an analytical conference, so naturally my talk will be about analytical chemistry and how analytical chemistry will become increasingly important in delivering healthcare solutions, not only for rich people, but also, hopefully, for poor people across the world.

From Pittcon 19 Sep 2017

Evosep launches new separation technology tailored for clinical omics at HUPO 2017

Evosep aims to improve quality of life and patient care by radically innovating protein based clinical diagnostics. We will make sample preparation and separation for mass spectrometry analysis 100 times more robust and 10 times faster to enable truly large cohort studies and provide the foundation for precision medicine.

From Evosep 19 Sep 2017

Study finds diet as important predictor of type 2 diabetes risk

A pioneering method, developed at Chalmers University of Technology, has demonstrated its potential in a large study, showing that metabolic fingerprints from blood samples could render important new knowledge on the connection between food and health.

14 Sep 2017