Clinical Trial News and Research

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B vitamins do not prevent Alzheimer's disease

Taking B vitamins doesn't slow mental decline as we age, nor is it likely to prevent Alzheimer's disease, conclude Oxford University researchers who have assembled all the best clinical trial data involving 22,000 people to offer a final answer on this debate.

15 Jul 2014

Study pinpoints molecular cause of cachexia, hints at a potential treatment

New research raises the prospect of more effective treatments for cachexia, a profound wasting of fat and muscle occurring in about half of all cancer patients, raising their risk of death, according to scientists from Dana-Farber Cancer Institute.

14 Jul 2014

Noninvasive optical imaging device helps to detect changes linked with Alzheimer's disease

A noninvasive optical imaging device developed at Cedars-Sinai can provide early detection of changes that later occur in the brain and are a classic sign of Alzheimer's disease, according to preliminary results from investigators conducting a clinical trial in Australia.

14 Jul 2014

Young adults reduce binge drinking after receiving text messages following visit to ER

Young adults who screened positive for a history of hazardous or binge drinking reduced their binge drinking by more than 50 percent after receiving mobile phone text messages following a visit to the emergency department, according to a study published online yesterday in Annals of Emergency Medicine ("A Text Message Alcohol Intervention for Young Adult Emergency Department Patients: A Randomized Clinical Trial").

14 Jul 2014

Cataract surgery for people with dementia slows cognition decline, improves quality of life

Cataract surgery for people with Alzheimer's disease and other dementias not only improves vision but can slow decline in cognition and improve quality of life for both people with the disease and their caregivers, according to clinical trial results reported today at the Alzheimer's Association International Conference 2014 (AAIC 2014) in Copenhagen.

13 Jul 2014

Veran announces positive, final results for initial study of SPiNPerc procedure

Veran Medical Technologies, a U.S. based medical device company, announced today the positive, cost-effective final results for the initial study of its innovative SPiNPerc procedure.

11 Jul 2014

HIV detected in Mississippi baby after apparent cure

In November 2013, it was reported that an infant (known as the “Mississippi baby”) had been in prolonged remission from HIV and was apparently cured. However, after 2 years without taking antiretroviral therapy and having no evidence of the virus, the child now has detectable levels of HIV.

11 Jul 2014

Use of electronic health records simplifies clinical trials

Using electronic health records to understand the best available treatment for patients, from a range of possible options, is more efficient and less costly for taxpayers than the existing clinical trial process, a new study shows.

From The University of Manchester 11 Jul 2014

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

The child known as the "Mississippi baby"-an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in The New England Journal of Medicine last fall-now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case.

11 Jul 2014

Baxter International acquires drug candidate developed to treat sickle cell disease

A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business.

11 Jul 2014

Reducing amount of alcoholic beverages consumed may improve cardiovascular health

Reducing the amount of alcoholic beverages consumed, even for light-to-moderate drinkers, may improve cardiovascular health, including a reduced risk of coronary heart disease, lower body mass index (BMI) and blood pressure, according to a new multi-center study published in The BMJ and co-led by the Perelman School of Medicine at the University of Pennsylvania.

11 Jul 2014

New knowledge may expand treatments for patients with lung cancer

Studying the most common type of lung cancer, researchers have uncovered mutations in a cell-signaling pathway that plays a role in forming tumors.

10 Jul 2014

Trial to evaluate safety of FRED- flow diversion system for treatment of aneurysms

After Susan Wakulich was told she had an aneurysm, she figured an invasive brain surgery and lengthy recovery lay ahead of her.

10 Jul 2014

Penn receives $8 million grant from NCI to study effects of PDT

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute (NCI) to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

Immune marker predicts infection risk in critically ill children with traumatic injuries

Researchers studying critically ill children with traumatic injuries have identified an immune marker that predicts which patients are likely to develop a hospital-acquired infection.

10 Jul 2014

NIAID launches CRS3123 Phase I trial to treat C. difficile infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched an early-stage clinical trial of CRS3123, an investigational oral antibiotic intended to treat Clostridium difficile (C. difficile) infection.

10 Jul 2014

NIH funds Phase II 90-subject pediatric clinical trial at UCLA

NeuroSigma, Inc., a California-based life sciences company focused on commercialization of its non-invasive Monarch eTNS System for the treatment of neurological and neuropsychiatric disorders, today announced that the U.S. National Institutes of Health (NIH) has awarded UCLA a grant that funds a Phase II 90-subject pediatric clinical trial at the University of California, Los Angeles focused on the treatment of Attention Deficit Hyperactivity Disorder (ADHD) with NeuroSigma's external trigeminal nerve stimulation (eTNS) System.

10 Jul 2014

Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

PTC Therapeutics initiates reimbursed expanded access program for Translarna

PTC Therapeutics, Inc. today announced the initiation of a reimbursed expanded access program (EAP). PTC's EAP program is intended to make Translarna (ataluren) available to patients before commercial availability in certain countries.

9 Jul 2014

Integrated therapies can reduce depression by half among people with low vision due to AMD

The first clinical trial to examine integrated low vision and mental health treatment has shown that the approach can reduce the incidence of depression by half among people with low vision due to age-related macular degeneration (AMD).

9 Jul 2014

Clinical Trial News and Research

B vitamins do not prevent Alzheimer's disease

Study pinpoints molecular cause of cachexia, hints at a potential treatment

Noninvasive optical imaging device helps to detect changes linked with Alzheimer's disease

Young adults reduce binge drinking after receiving text messages following visit to ER

Cataract surgery for people with dementia slows cognition decline, improves quality of life

Veran announces positive, final results for initial study of SPiNPerc procedure

HIV detected in Mississippi baby after apparent cure

Use of electronic health records simplifies clinical trials

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

Baxter International acquires drug candidate developed to treat sickle cell disease

Reducing amount of alcoholic beverages consumed may improve cardiovascular health

New knowledge may expand treatments for patients with lung cancer

Trial to evaluate safety of FRED- flow diversion system for treatment of aneurysms

Penn receives $8 million grant from NCI to study effects of PDT

Immune marker predicts infection risk in critically ill children with traumatic injuries

NIAID launches CRS3123 Phase I trial to treat C. difficile infection

NIH funds Phase II 90-subject pediatric clinical trial at UCLA

Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

PTC Therapeutics initiates reimbursed expanded access program for Translarna

Integrated therapies can reduce depression by half among people with low vision due to AMD

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