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Graphene oxide-silver nanoparticles shown to rapidly neutralize RNA viruses

While the vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are administered, and extensive research is conducted for targeted therapeutics to control the COVID-19 (coronavirus disease 2019), it is equally crucial to develop more novel, broad-spectrum antiviral compounds.

2 Mar 2021

Biological activity-based modeling offers a new approach for drug discovery

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

Researchers explore early stages of ribosome formation to identify new targets for antibiotics

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process.

2 Mar 2021

Loss of functions in the PLD1 gene causes congenital heart disease

A team of researchers co-led by Michael Frohman, MD, PhD, of Stony Brook University, has identified an important cause of congenital heart disease.

2 Mar 2021

Hydroxychloroquine should not be used to prevent COVID-19, says WHO expert panel

The anti-inflammatory drug hydroxychloroquine should not be used to prevent infection in people who do not have covid-19, say a WHO Guideline Development Group (GDG) panel of international experts in The BMJ today.

2 Mar 2021

Study reveals presence of glial plasticity, offers future therapeutic strategy for epilepsy

Tohoku University scientists and their colleagues in Germany have revealed that a first-time exposure to only a brief period of brain hyperactivity resulted in an acute breakdown of the inter-cellular network of glial cells.

2 Mar 2021

UTMB researchers pioneer a new way to study frustration as a factor in substance use disorders

A team from The University of Texas Medical Branch at Galveston (UTMB) focused on drug addiction research have pioneered a new way to study frustration as a factor in substance use disorders.

1 Mar 2021

Lung cancer cells activate different signaling pathways in response to KRAS inhibitors

Genetic alterations of the KRAS gene are some of the most common mutations in lung cancer patients, but unfortunately these patients have few effective treatment options.

1 Mar 2021

A new hub established for development of oligonucleotide drugs

In recent years, techniques have been developed to treat diseases with what are known as oligonucleotide drugs, based on short DNA or RNA molecules.

1 Mar 2021

New technique uncovers the tricks used by cancer cells to evade immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

1 Mar 2021

Scientists test the effect of natural product isolated from sea sponge on cancer cells

Scientists from Far Eastern Federal University together with Russian and German colleagues, continue studying antitumor compounds synthesized based on bioactive molecules isolated from a sea sponge.

1 Mar 2021

A region within GLI1 gene could potentially be targeted as cancer treatment

Scientists from the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene's expression.

1 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

Protein kinase inhibitors could help treat immunodeficiency in HIV patients

HIV infections are treated with antiviral drugs which effectively prevent the disease from developing. While pharmacological HIV therapy has advanced considerably, the virus cannot be entirely eliminated from the body with currently available drugs.

1 Mar 2021

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

Scientists compared the in vitro efficacy and cytotoxicity profiles of PF-00835231 and remdesivir in two human model systems for SARS-CoV-2 infection.

1 Mar 2021

FDA clears new robotically-assisted surgical device for transvaginal hysterectomy

The U.S. Food and Drug Administration has authorized marketing of the Hominis Surgical System, a new robotically-assisted surgical device (RASD) that can help facilitate transvaginal hysterectomy in certain patients.

1 Mar 2021

FDA grants emergency use authorization for QuickVue At-Home COVID-19 Test

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the Quidel QuickVue At-Home COVID-19 Test, another antigen test where certain individuals can rapidly collect and test their sample at home, without needing to send a sample to a laboratory for analysis.

1 Mar 2021

New method boosts research efforts to eradicate cancer at its source

A new method, described in a study published today in the journal Nature Communications, has the potential to boost international research efforts to find drugs that eradicate cancer at its source.

1 Mar 2021

FDA issues EUA for third COVID-19 vaccine

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the third vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Mar 2021

Bacteria use slimy strategy to defeat antibiotics that fight cystic fibrosis

University of Montana researchers and their partners have discovered a slimy strategy used by bacteria to defeat antibiotics and other drugs used to combat infections afflicting people with cystic fibrosis. The research was published Feb. 23 in the journal Cell Reports.

27 Feb 2021

Drugs News and Research

Graphene oxide-silver nanoparticles shown to rapidly neutralize RNA viruses

Biological activity-based modeling offers a new approach for drug discovery

Researchers explore early stages of ribosome formation to identify new targets for antibiotics

Loss of functions in the PLD1 gene causes congenital heart disease

Hydroxychloroquine should not be used to prevent COVID-19, says WHO expert panel

Study reveals presence of glial plasticity, offers future therapeutic strategy for epilepsy

UTMB researchers pioneer a new way to study frustration as a factor in substance use disorders

Lung cancer cells activate different signaling pathways in response to KRAS inhibitors

A new hub established for development of oligonucleotide drugs

New technique uncovers the tricks used by cancer cells to evade immunotherapies

Scientists test the effect of natural product isolated from sea sponge on cancer cells

A region within GLI1 gene could potentially be targeted as cancer treatment

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

Protein kinase inhibitors could help treat immunodeficiency in HIV patients

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

FDA clears new robotically-assisted surgical device for transvaginal hysterectomy

FDA grants emergency use authorization for QuickVue At-Home COVID-19 Test

New method boosts research efforts to eradicate cancer at its source

FDA issues EUA for third COVID-19 vaccine

Bacteria use slimy strategy to defeat antibiotics that fight cystic fibrosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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