Immune System News and Research

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Diet and antibiotic use can change gut microbiota contributing to IBS symptoms

A recent review of research suggests that changes to the microorganisms (microbiota) in the gastrointestinal (GI) tract may be a cause of irritable bowel syndrome (IBS).

27 Jan 2017

Genetic makeup of social partners influences health, mice study shows

Researchers at the European Bioinformatics Institute (EMBL-EBI) have shown that the health of individual mice is influenced by the genetic makeup of their partners. Their findings, published in PLOS Genetics, indicate that research into genetics and disease should include the genotypes of both individuals and their partners.

27 Jan 2017

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.

27 Jan 2017

New gene therapy for Pompe disease may replace currently available treatments

After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients.

27 Jan 2017

UCL researchers discover how HIV infects macrophages despite presence of protective protein

A team led by UCL researchers has identified how HIV is able to infect macrophages, a type of white blood cell integral to the immune system, despite the presence of a protective protein.

27 Jan 2017

NIH scientists improve understanding of antibody-based protection against klebsiella bacteria

Klebsiella bacteria cause about 10 percent of all hospital-acquired infections in the United States. K. pneumoniae sequence type 258 (ST258) is one of the Carbapenem-Resistant Enterobacteriaceae organisms labeled an urgent threat by the Centers for Disease Control and Prevention.

27 Jan 2017

Johns Hopkins researchers create mature cardiomyocytes in the laboratory from stem cells

Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists.

26 Jan 2017

Scientists discover critical role of biological molecule in protecting against infection

Scientists have discovered that a biological molecule important in cell growth (STAT3) is also critical in protecting us against infection - so much so that we would be unable to fight the common flu virus without it.

26 Jan 2017

Researchers show how social environment can have large impact on weight and health in mice

The genetics of nearby mice can have a large impact on one animal's weight and health, according to a report by Amelie Baud and Oliver Stegle of the European Bioinformatics Institute (EMBL - EBI) in Hinxton, United Kingdom, published on January 25th, 2017 in PLOS Genetics.

25 Jan 2017

Researchers design antibody that recognizes and destroys blood cancer stem cells

A protein-sugar molecule, CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) and the related myelodysplastic syndromes.

25 Jan 2017

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo.

25 Jan 2017

Combination of broadly neutralizing antibodies can suppress virus in HIV-infected mice, study shows

Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body's ability to control it.

25 Jan 2017

Shorter chromosome 'caps' linked to higher burden of disease later in life

New research indicates that people who had more infections as babies harbor a key marker of cellular aging as young adults: the protective stretches of DNA which "cap" the ends of their chromosomes are shorter than in adults who were healthier as infants.

25 Jan 2017

TSRI researchers develop first stable semisynthetic single-celled organism

Life’s genetic code has only ever contained four natural bases. These bases pair up to form two “base pairs”—the rungs of the DNA ladder—and they have simply been rearranged to create bacteria and butterflies, penguins and people. Four bases make up all life as we know it.

25 Jan 2017

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

Maternal infection during pregnancy increases the risk for psychiatric disorders in the child, but the path between the two is something of a mystery.

25 Jan 2017

Researchers suggest new approach to slow cancer growth using tumor-derived dendritic cells

In the human body, so-called dendritic cells are responsible for activating our immune system. While researchers previously believed that tumors could repress these dendritic cells - blocking an adequate natural cancer defense mechanism - a new study has painted a more positive picture.

25 Jan 2017

Timing of chemotherapy can have big effect on inflammation, study shows

The time of day that breast cancer chemotherapy drugs are given affects the amount of damaging inflammation in the body, a new study in mice suggests.

24 Jan 2017

Scientists decipher mechanism of CA-MRSA that plays role in development of skin infections

Staphylococcus aureus is one of the most feared, multi-resistant pathogens. The bacterium often causes life-threatening infections, particularly in people with a weakened immune system.

24 Jan 2017

Penn researchers unravel missing steps involved in movement of cellular cargo

Every time a hormone is released from a cell, every time a neurotransmitter leaps across a synapse to relay a message from one neuron to another, the cell must undergo exocytosis.

24 Jan 2017

Quest Diagnostics introduces new HBV test service to help evaluate patient’s response to drug therapies

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced the launch of a new test service that helps physicians evaluate a patient’s response to drug therapies used to treat infection with the hepatitis B virus

24 Jan 2017

Immune System News and Research

Diet and antibiotic use can change gut microbiota contributing to IBS symptoms

Genetic makeup of social partners influences health, mice study shows

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

New gene therapy for Pompe disease may replace currently available treatments

UCL researchers discover how HIV infects macrophages despite presence of protective protein

NIH scientists improve understanding of antibody-based protection against klebsiella bacteria

Johns Hopkins researchers create mature cardiomyocytes in the laboratory from stem cells

Scientists discover critical role of biological molecule in protecting against infection

Researchers show how social environment can have large impact on weight and health in mice

Researchers design antibody that recognizes and destroys blood cancer stem cells

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Combination of broadly neutralizing antibodies can suppress virus in HIV-infected mice, study shows

Shorter chromosome 'caps' linked to higher burden of disease later in life

TSRI researchers develop first stable semisynthetic single-celled organism

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

Researchers suggest new approach to slow cancer growth using tumor-derived dendritic cells

Timing of chemotherapy can have big effect on inflammation, study shows

Scientists decipher mechanism of CA-MRSA that plays role in development of skin infections

Penn researchers unravel missing steps involved in movement of cellular cargo

Quest Diagnostics introduces new HBV test service to help evaluate patient’s response to drug therapies

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