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NSAIDs okay for tonsillectomy, new study finds

When children have their tonsils removed, nonsteroidal anti-inflammatory drugs can be used for pain relief with no significant increase in bleeding and with less nausea and vomiting, according to a systematic review of current evidence.

19 Apr 2005

Clinical trial of gefitinib for advanced lung cancer closes early

Researchers have closed a randomized clinical trial comparing gefitinib (Iressa) vs. placebo following chemotherapy and radiation for patients with non-small cell lung cancer (NSCLC) that had spread only to nearby tissues or lymph nodes. Review of interim data indicated that gefitinib would not improve survival.

19 Apr 2005

Rimonabant appears to reduce risk factors for heart disease in obese people

A new drug could substantially reduce the bodyweight, waist circumference, and risk factors for heart disease in obese people, according to results of a randomised trial published in this week’s issue of The Lancet.

19 Apr 2005

Neurologists may have foot in the door to preventing Alzheimer’s before it starts

A study led by Mayo Clinic shows for the first time that a drug appears to have a slowing effect -- though limited -- on the progression from mild cognitive impairment to Alzheimer's disease. The findings will be published online in the New England Journal of Medicine on April 14.

13 Apr 2005

Clinical diagnosis of Alzheimer's may be delayed

In a study of people with mild cognitive impairment (MCI), those who took the drug donepezil were at reduced risk of progressing to a diagnosis of Alzheimer's disease (AD) during the first year of the trial, but by the end of the 3-year study there was no benefit from the drug. Vitamin E was also tested in the study and was found to have no effect at any time point in the study when compared with placebo.

13 Apr 2005

Drug that reduces the pain of fibromyalgia and improves sleep

A study of a drug that reduces the pain of fibromyalgia and improves sleep is published by a University of Kentucky physician in the peer-reviewed journal, Arthritis & Rheumatism.

12 Apr 2005

Consent forms should be more readable

When children are part of a clinical trial, their parents must sign a document agreeing to the treatment and procedures used in the study. But what if they don't understand what they're being asked to sign?

12 Apr 2005

Vaccine against the virus that causes cervical cancer and genital warts shows promise

A vaccine against the virus that causes cervical cancer and genital warts could reduce persistent infection and disease by 90%, suggest the results of a randomised trial published online by The Lancet Oncology.

12 Apr 2005

FDA issues public health advisory for antipsychotic drugs

The Food and Drug Administration (FDA) has issued a public health advisory to alert health care providers, patients, and patient caregivers to new safety information concerning an unapproved (i.e., “off-label”) use of certain drugs called “atypical antipsychotic drugs.”

12 Apr 2005

FDA wants warnings put on antipsychotic drugs

The Food and Drug Administration (FDA) has issued a public health advisory to health care providers, patients, and caregivers to alert them to new safety information about the use of certain unapproved or off label drugs which come under the category of “atypical antipsychotic drugs.”

11 Apr 2005

Moderate levels of exercise may not be enough to control mild hypertension

Moderate levels of exercise may not be enough to control mild hypertension in men and women over age 55, the age group most at risk of later developing potentially fatal heart failure, a new four-year study reports. The findings by researchers at Johns Hopkins, to be published in the journal Archives of Internal Medicine online April 11, call into question the effectiveness of national guidelines on exercise for lowering blood pressure in older people.

11 Apr 2005

Now revealed that Salk polio vaccine was a team effort

The cure for polio came as a result of the collaboration between Thomas Francis Jr. and Jonas Salk.

10 Apr 2005

Cyclosporine inhalation solution (CyIS) significantly improves long-term survival in lung-transplant patients

Data presented for the first time at the 25th Annual Meeting and Scientific Session of the International Society for Heart and Lung Transplantation (ISHLT) show that cyclosporine inhalation solution (CyIS) significantly improves long-term survival in lung-transplant patients compared to placebo.

10 Apr 2005

Race to market cancer vaccine

In a race to market the first vaccine against the virus that causes cervical cancer and genital warts drug manufacturers Merck & Co Inc. and GlaxoSmithKline plc are in head-to-head competition.

7 Apr 2005

Naltrexone combined with psychotherapy helps treat alcohol dependence

Long-acting injections of the drug naltrexone, combined with psychotherapy, significantly reduced heavy drinking in patients being treated for alcohol dependence, according to a study in the Journal of the American Medical Association by a Yale School of Medicine researcher.

7 Apr 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005

Vaccine against cervical cancer and genital warts looks hopeful

More than two thirds of sexually active women will become infected with human papillomavirus (HPV) during their lifetime. HPV causes around 470 000 cases of cervical cancer each year and even though most cases of cervical cancer occur in the developing world, where cervical screening programmes are in the main non-existent, in Europe and the US 35000 women die from the disease every year.

6 Apr 2005

Promising new treatment for alcohol dependence

According to the World Health Organization's Global Burden of Disease project, alcohol dependence, a major public health problem, ranks fourth as one of the worlds leading cause of disability. In the US alone over 100,000 deaths each year, where alcohol was a contributing factor, could have been prevented.

6 Apr 2005

Osteoporosis drug reduces women's risk of mild cognitive impairment

A drug prescribed for the prevention of osteoporosis reduced women's risk of mild cognitive impairment by 33 percent in a worldwide clinical trial led by researchers at San Francisco VA Medical Center (SFVAMC).

6 Apr 2005

Fish oil, soluble fiber and antioxidants reduces need for traditional ulcerative colitis treatment

According to a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, a nutritionally complete oral supplement enriched with fish oil, soluble fiber and antioxidants reduces reliance on traditional therapies for people with ulcerative colitis.

6 Apr 2005