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Gene therapy shows effect in heart patients

The first double-blind, placebo-controlled randomized trial of VEGF gene injections into the heart muscle of patients with coronary artery disease with the intention of spurring growth of new blood vessels showed significant effects on heart wall motion, although blood flow was not significantly better in treated patients, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Cognitive therapy to treat moderate to severe depression works just as well as antidepressants

The study, conducted by researchers at the University of Pennsylvania and Vanderbilt University, challenges the American Psychiatric Association guidelines that antidepressant medications are the only effective treatment for moderately to severely depressed patients.

5 Apr 2005

Nasal filter new weapon against hay fever

The first clinical trial of a nasal filter has shown that they can significantly reduce both the number of people experiencing symptoms and the severity of their symptoms.

5 Apr 2005

Vitamin E supplements speed up the development of latent cancers

Taking high-dose vitamin E supplements for an extended period doesn't protect against cancer; in fact, it may even speed up the development of latent cancers, according to a study by researchers from Hotel-Dieu de Quebec Research Centre and Universite Laval. Their results are published in the April issue of the prestigious Journal of the National Cancer Institute.

5 Apr 2005

Men have a four times greater risk than women of developing abdominal aortic aneurysms

Men have a four times greater risk than women of developing abdominal aortic aneurysms, estimated to be the cause of death in 4 percent of people over the age of 65, but the mechanism for this higher incidence has remained unknown.

4 Apr 2005

Zinc appears to help boys learn

Seventh graders given 20 mg zinc, five days per week, for 10 to 12 weeks showed improvement in mental performance, responding more quickly and accurately on memory tasks and with more sustained attention, than classmates who received no additional zinc.

4 Apr 2005

Cognitive therapy may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression

Cognitive therapy, when provided by an experienced therapist, may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression, according to an article in the April issue of Archives of General Psychiatry.

4 Apr 2005

Chronic pain treatments more effective when taken together

People suffering from chronic, debilitating pain caused by nerve damage or disease report better pain relief at lower doses of a combined drug treatment than from either drug administered individually, a new Queen’s study funded by the Canadian Institutes of Health Research (CIHR) shows.

3 Apr 2005

New trial for treatment of liver disease

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network is launching its first two clinical trials for the study of NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol.

3 Apr 2005

Pediatric burn victims’ recovery, diabetes aided by Fenofibrate

One of the immediate serious results of sudden extreme trauma or stress, including burns and even surgery, is insulin resistance, or diabetes. As a result, healing is delayed, especially in the case of severe burns, and since the body is unable to fully use blood sugar for energy, muscle tissue is broken down as the body scavenges for other possible energy sources.

3 Apr 2005

Finding opens new doors to determining susceptibility to antidepressant side effects

In a finding that opens new doors to determining susceptibility to antidepressant side effects, researchers at the UCLA Neuropsychiatric Institute report that changes in brain activity prior to treatment with antidepressants can flag patient vulnerability.

30 Mar 2005

First North American trial to evaluate the role of an aromatase inhibitor in the prevention of breast cancer

Today, a new clinical trial evaluating a novel approach to breast cancer prevention launched in the United States and Canada. Called the ExCel research study, this is the first North American clinical trial to evaluate the role of an aromatase inhibitor in the prevention of breast cancer.

30 Mar 2005

High-rise homes have the highest levels of cockroach allergens

Roaches like to live high in the sky in places like Chicago, New York City and the Bronx, according to a recent study in the Journal of Allergy and Clinical Immunology. The study, conducted by an allergist affiliated with Children's Medical Center Dallas, found high-rise homes in Northeastern cities had the highest levels of cockroach allergens -- leading to a higher incidence of asthmatic episodes.

30 Mar 2005

Vaccine prevents deadly pneumonia in African children

Global health leaders today presented new research showing that vaccinating infants against Streptococcus pneumoniae -- a bacterium that causes deadly pneumonia, meningitis and sepsis -- could substantially reduce death and serious illness among children in the developing world. If used widely, a pneumococcal conjugate vaccine could prevent hundreds of thousands of child deaths each year.

28 Mar 2005

Statins appear to be safe for people with fatty liver disease

Statins appear to be safe for people with fatty liver disease who could benefit from their cholesterol-lowering capabilities, concludes a review paper published in the April 2005 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD).

28 Mar 2005

Patients with chronic fatigue syndrome respond to placebos at a lower rate

Contrary to conventional wisdom, patients with chronic fatigue syndrome respond to placebos at a lower rate than people with many other illnesses, according to the first systematic review of the topic.

22 Mar 2005

Intervention with once-daily budesonide reduces long-term risk and frequency of severe asthma-related events

New data indicated that earlier intervention with once-daily budesonide, an inhaled corticosteroid delivered by dry powder inhaler to children with mild persistent asthma, significantly reduced the long-term risk and frequency of severe asthma-related events as well as the need for other inhaled medication.

21 Mar 2005

Questions about validity of HOPE TOO vitamin E study

A study published in the March 16 issue of Journal of the American Medical Association (JAMA) suggesting that a "daily-dose" of vitamin E (400 international units) among high-risk (chronically ill) cardiovascular patient populations is associated with a greater risk of heart failure is being challenged by leading health researchers around the country who claim the study lacks the adequate research and controlled sampling audience to justify this conclusion.

16 Mar 2005

Vitamin E may increase heart attack risk - does not prevent cancer

A study by Canadian researchers Eva Lonn, M.D., of the Population Health Research Institute and McMaster University, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada, and colleagues, has found from examining experimental and epidemiological data, that patients who took vitamin E supplements for 7 years did not significantly reduce their risk of cancer or cardiovascular events and some in fact had an increased risk of heart failure.

15 Mar 2005

Study indicates that vitamin E does not prevent cancer

Patients who took vitamin E supplements for about 7 years did not have their risk of cancer or cardiovascular events significantly reduced, and in fact some had an increased risk of heart failure, according to a study in the March 16 issue of JAMA.

15 Mar 2005