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Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

The U.S. Food and Drug Administration yesterday granted accelerated approval to the checkpoint inhibitor Bavencio (avelumab) for the treatment of patients with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

25 Mar 2017

Excessive sweating could be hyperhidrosis that often goes undiagnosed

Hyperhidrosis is excessive sweating that is more than what is needed to regulate body temperature. About 7 million Americans suffer from hyperhidrosis, a disorder that often goes undiagnosed.

24 Mar 2017

Study finds direct link between increasing width of vestibular aqueduct and severity of child's hearing loss

It may be possible to predict the severity of hearing loss for children diagnosed with enlarged vestibular aqueduct, according to a new study published in JAMA-Otolaryngology-Head & Neck Surgery.

23 Mar 2017

Brain makes new connections in blind people to enhance compensatory abilities

The brains of those who are born blind make new connections in the absence of visual information, resulting in enhanced, compensatory abilities such as a heightened sense of hearing, smell and touch, as well as cognitive functions (such as memory and language) according to a new study led by Massachusetts Eye and Ear researchers.

23 Mar 2017

Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

In a first-of-its-kind study published in the March 1, 2017 edition of Molecular Therapy, researchers from the National Institute on Deafness and Other Communication Disorders and Johns Hopkins University School of Medicine showed that gene therapy was able to restore balance and hearing in genetically modified mice that mimic Usher Syndrome, a genetic condition in humans characterized by partial or total hearing loss, dizziness, and vision loss that worsens over time.

23 Mar 2017

New clinical approach offers hope for patients with aggressive brain cancer

Being diagnosed with a malignant brain tumor is devastating news for patients and their loved ones. Whereas some types of tumor respond well to treatment, others such as glioblastomas - the most common and aggressive brain tumors - are known to recur and progress within short times from the diagnosis.

23 Mar 2017

Genome sequencing approach opens door to therapy options for rare, neglected cancers

An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer.

23 Mar 2017

Swedish researchers prove that 3D bioprinted human cartilage cells can be implanted

Swedish researchers at Chalmers University of Technology and Sahlgrenska Academy have successfully induced human cartilage cells to live and grow in an animal model, using 3D bioprinting.

23 Mar 2017

New research reveals impact of 3D printing technology in medical devices and pharmaceutical sector

3D printing technology is the ideal solution for the healthcare industry’s need for the efficient production of complex and personalized products.

23 Mar 2017

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Heroin use linked to epigenetic alterations in the brain

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

22 Mar 2017

Educational module can effectively train large workforce in hemorrhage control techniques

A medical team has developed a way to effectively provide a large group of people with basic knowledge and skills to locate and use bleeding control equipment to stop life-threatening bleeding in severely injured people.

22 Mar 2017

Study evaluates screening and treatment for subclinical thyroid disease during pregnancy

Observational studies over the past 30 years suggest that subclinical thyroid disease during pregnancy may be associated with adverse outcomes, including a lower-than-normal IQ in offspring.

22 Mar 2017

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.

22 Mar 2017

National Joint Registry study finds disparities in hip or knee joint replacements for ethnic minorities

Researchers have found that the number of both hip and knee replacement operations for Black and Asian ethnic minorities are lower than expected when compared to Whites.

22 Mar 2017

New recommendations aim to guide doctors and patients about testing, treatment options

Surgical options for people with medical conditions including obesity, and the risks of operating on the elderly, feature among 10 new recommendations released today under the Choosing Wisely Australia initiative.

22 Mar 2017

Day of the week has no effect on survival chances of people undergoing emergency surgery, study finds

Day of the week did not affect the survival chances of people undergoing emergency surgery, research has found.

22 Mar 2017

USC study close to finding gene involved in cleft lip and palate

A group of researchers has found that three siblings born with cleft lip and palate share a common gene mutation associated with the birth defect.

22 Mar 2017

Study reveals link between tanning dependence and other addictive behaviors

Despite the known dangers of exposure to ultraviolet light, many people continue to sunbathe and use indoor tanning beds with some users exhibiting a dependence to tanning. A new study from the Yale School of Public Health finds that such dependence is also associated with other addictive behaviors.

21 Mar 2017

Vanderbilt study compares side effects, outcomes of prostate cancer treatments with active surveillance

Faced with the negative quality-of-life effects from surgery and radiation treatments for prostate cancer, low risk patients may instead want to consider active surveillance with their physician, according to a study released Tuesday by the Journal of the American Medical Association

21 Mar 2017

Surgery News and Research

Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

Excessive sweating could be hyperhidrosis that often goes undiagnosed

Study finds direct link between increasing width of vestibular aqueduct and severity of child's hearing loss

Brain makes new connections in blind people to enhance compensatory abilities

Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

New clinical approach offers hope for patients with aggressive brain cancer

Genome sequencing approach opens door to therapy options for rare, neglected cancers

Swedish researchers prove that 3D bioprinted human cartilage cells can be implanted

New research reveals impact of 3D printing technology in medical devices and pharmaceutical sector

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Heroin use linked to epigenetic alterations in the brain

Educational module can effectively train large workforce in hemorrhage control techniques

Study evaluates screening and treatment for subclinical thyroid disease during pregnancy

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

National Joint Registry study finds disparities in hip or knee joint replacements for ethnic minorities

New recommendations aim to guide doctors and patients about testing, treatment options

Day of the week has no effect on survival chances of people undergoing emergency surgery, study finds

USC study close to finding gene involved in cleft lip and palate

Study reveals link between tanning dependence and other addictive behaviors

Vanderbilt study compares side effects, outcomes of prostate cancer treatments with active surveillance

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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