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Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provides a potential new approach for treating a variety of diseases including cancer, viral infections, cardiovascular and muscle diseases.

21 Mar 2011

Ibuprofen - painkiller toxicity warning

In a recent development, doctors have warned regarding the possibly toxicities of common pain killer Ibuprofen adding that it can lead to a potentially fatal condition which can be triggered, in rare cases, by even a standard dose. The condition in question is called renal tubular acidosis (RTA). The research is published in the Medical Journal of Australia.

21 Mar 2011

New insight into Duchenne muscular dystrophy

Armed with a zebrafish model of Duchenne muscular dystrophy and a library of 1,200 chemicals already approved for human use, researchers at Children's Hospital Boston have identified a compound that reverses the loss of muscle structure and function associated with DMD, seemingly by compensating for the loss of a critical protein.

19 Mar 2011

Nature's Health announces record sales of 145% for Australian Dream pain relief cream

Nature's Health Connection has announced record sales of their Australian Dream pain relief cream. After a successful television advertising campaign produced by CPG specialists Western Creative, Inc. that highlights Australian Dream's Empty Jar Guarantee, unit retail sales of the product have increased an astonishing 145% over the course of the last year.

18 Mar 2011

Science journal publishes CYTK preclinical cardiac myosin activation research results

Cytokinetics, Incorporated announced today the publication of preclinical research in the March 18, 2011 issue of the journal Science regarding the activation of cardiac myosin by an investigational drug candidate, omecamtiv mecarbil, and the potential therapeutic role that this novel mechanism may play for patients with systolic heart failure.

18 Mar 2011

Researchers develop diagnostic test for motor neurone disease

NeuRA researchers are one step closer to developing a diagnostic test for motor neurone disease. Dr Steve Vucic, from Neuroscience Research Australia, says the test will allow people with motor neurone disease to be diagnosed up to eight months earlier than is currently possible.

17 Mar 2011

Stem cell therapy successfully heals a scarred and failing heart

A new study has shown that stem cells could heal scars caused by old heart attacks. In all eight patients who received the experimental treatment in an ongoing clinical trial this therapy worked. All of them had suffered heart attacks an average of 5 1/2 years prior; one of the patients had his heart attack 11 years earlier.

17 Mar 2011

Gene therapy for Parkinson’s: It works!

A latest study has shown that gene therapy may be successful in treating the dreaded brain degenerative disease – Parkinson’s disease. Neurologists are hopeful that it could be useful in other neurologic disorders too.

17 Mar 2011

PsiOxus commences MT-102 Phase II study for treatment of cancer- and age-related wasting

PsiOxus Therapeutics, Ltd. announced initiation of a Phase II study of MT-102, a small molecule therapeutic for the treatment of cancer- and age-related wasting. MT-102 is being developed to reverse the effects of cachexia, a wasting disease that accompanies cancer, heart failure, COPD, renal failure, cirrhosis and rheumatoid arthritis, and that is associated with significant morbidity and mortality.

17 Mar 2011

Children and youth with IBD have 25% lower aerobic fitness levels

Children and adolescents growing up with inflammatory bowel disease are less fit than their peers, says a study by researchers at McMaster University and the McMaster Children's Hospital.

17 Mar 2011

Electric devices can improve aging skin

It may seem as if new developments to combat aging skin are being introduced faster than the speed of light. At the forefront of the research, dermatologists are underpinning these advancements, refining the basic understanding of how the skin ages in order to develop more effective non-invasive cosmetic procedures and products.

16 Mar 2011

NAFC honors Florida's Cleveland Clinic physician with Continence Care Champion Award

The National Association For Continence awarded Gamal Ghoniem, MD, with the Rodney Appell Continence Care Champion Award at the Society for Urodynamics and Female Urology Awards Reception on March 4, held during the 2011 SUFU Winter Meeting in Phoenix, AZ.

16 Mar 2011

Researchers identify genetic cause of magnesium deficiency

Researchers and scientists of the Charité - Universitätsmedizin Berlin, in cooperation with the Max Delbrück Center for Molecular Medicine, and colleagues from the Netherlands, Belgium, Switzerland and the Czech Republic have succeeded in identifying a genetic cause of magnesium deficiency.

16 Mar 2011

eToims launches new program with leading football franchise to improve athletic therapy

eToims Medical Technology has announced an innovative Sports Development Program with a leading UK football franchise to refine and improve athletic therapy and conditioning.

15 Mar 2011

Challenge Problems in mathematical cardiology

Did you know that heart attacks can give you mathematics? That statement appears on the web site of James Keener, who works in the mathematics of cardiology. This area has many problems that are ripe for unified attack by mathematicians, clinicians, and biomedical engineers.

15 Mar 2011

Nanoscale whiskers could hold key to creating working human muscle tissue

Minute whiskers of nanoscale dimensions taken from sea creatures could hold the key to creating working human muscle tissue, University of Manchester researchers have discovered.

14 Mar 2011

Majority of Americans fall short of vitamin D

Well-known for its role in keeping bones strong, vitamin D is now being hailed for so much more – from normal muscle function to a healthy immune system. Yet despite the growing research on the power of vitamin D, seven out of 10 Americans still fall short of the recommended vitamin D in their diets each day, according to the recent Dietary Guidelines Committee Advisory report.

14 Mar 2011

Majority of men on ADT after prostatectomy gain weight during first year of therapy

Seventy per cent of men who received androgen-deprivation therapy (ADT) after surgery to remove their prostate gland gained significant weight in the first year, putting on an average of 4.2kg, according to a paper in the March issue of the urology journal BJUI.

11 Mar 2011

FMCNA encourages high blood pressure, diabetes people to learn about risk of CKD

Diabetes and high blood pressure are the two leading causes of chronic kidney disease, a health problem that is growing at an alarming rate in the United States. There are 26 million Americans who have CKD, and millions more are at increased risk and may not even know it.

11 Mar 2011

GSK announces new NovaMin-containing dental formulation for sensitive teeth

This year, for the first time, millions of Americans will be protecting their sensitive teeth with NovaMin in everyday dental products. Co-inventor Gary Hack, DDS, couldn't be happier.

11 Mar 2011

Muscle News and Research

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

Ibuprofen - painkiller toxicity warning

New insight into Duchenne muscular dystrophy

Nature's Health announces record sales of 145% for Australian Dream pain relief cream

Science journal publishes CYTK preclinical cardiac myosin activation research results

Researchers develop diagnostic test for motor neurone disease

Stem cell therapy successfully heals a scarred and failing heart

Gene therapy for Parkinson’s: It works!

PsiOxus commences MT-102 Phase II study for treatment of cancer- and age-related wasting

Children and youth with IBD have 25% lower aerobic fitness levels

Electric devices can improve aging skin

NAFC honors Florida's Cleveland Clinic physician with Continence Care Champion Award

Researchers identify genetic cause of magnesium deficiency

eToims launches new program with leading football franchise to improve athletic therapy

Challenge Problems in mathematical cardiology

Nanoscale whiskers could hold key to creating working human muscle tissue

Majority of Americans fall short of vitamin D

Majority of men on ADT after prostatectomy gain weight during first year of therapy

FMCNA encourages high blood pressure, diabetes people to learn about risk of CKD

GSK announces new NovaMin-containing dental formulation for sensitive teeth

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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