Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Lithium aspartate fails to improve long COVID symptoms, but higher doses may hold promise

Lithium aspartate at 10-15 mg/d is ineffective for treating cognitive dysfunction and fatigue in long COVID, but higher doses may offer potential benefits based on a small follow-up study.

3 Oct 2024

Non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma

A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer.

3 Oct 2024

Circadian rhythm influences dementia diagnosis and disease progression

The time of day when blood is taken can affect the results of tests for diagnosing dementia, according to new research led by the University of Surrey.

3 Oct 2024

New treatment proposed for brain metastases resistant to immunotherapy

Researchers at the Spanish National Cancer Research Centre (CNIO) propose a new treatment for brain metastases that respond poorly, or not at all, to immunotherapy, and provide a biomarker to predict in which cases it should be used.

2 Oct 2024

Frailty linked to diminished quality of life in cancer and transplant survivors

A new research paper was published on the in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 18 on September 26, 2024, entitled, "Frailty and pre-frailty associated with long-term diminished physical performance and quality of life in breast cancer and hematopoietic cell transplant survivors."

2 Oct 2024

Researchers advance ovarian cancer detection using cfDNA fragmentomes and protein biomarkers

Researchers developed a groundbreaking method to detect ovarian cancer early by analyzing cfDNA fragmentomes and protein biomarkers, significantly improving sensitivity and specificity over existing approaches.

1 Oct 2024

Study reveals widespread long-COVID symptoms, challenging WHO definition

Study reveals that more than one-third of SARS-CoV-2 positive patients experience long-COVID symptoms three months after an emergency department visit, with significant overlap in symptoms observed among negative patients.

1 Oct 2024

Inflammatory proteins linked to higher risk of endometrial cancer

Study identifies key inflammatory and immune response proteins linked to endometrial cancer risk through both observational and Mendelian Randomization analyses, revealing the roles of IL-6 and HSD11B1.

1 Oct 2024

NIH grant supports research on cognitive decline in individuals with Lewy body diseases

Penn Medicine researchers will advance their understanding of the underlying causes of cognitive decline in individuals with Lewy body diseases, like Parkinson's, and identify biomarkers that predict which individuals are more likely to develop dementia with a $18 million grant from the National Institutes of Health/National Institute on Aging.

30 Sep 2024

Over 80% of women are iron deficient by their third trimester

Iron deficiency is prevalent among pregnant women, impacting health outcomes. This study emphasizes the importance of monitoring and nutrition during pregnancy.

30 Sep 2024

Owlstone Medical launches Breath Biopsy VOC Atlas® to unlock disease biomarkers in human breath

The Breath Biopsy VOC Atlas offers a comprehensive catalog of volatile organic compounds, enhancing understanding of breath biomarkers in health and disease.

From Owlstone Medical Ltd 30 Sep 2024

Study highlights potential for targeting macrophages to improve rheumatoid arthritis outcomes

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health system of ~€544 million.

27 Sep 2024

Advances in mitochondria-targeted medicine for TBI in military settings

During the 15th Annual Meeting of the World Mitochondria Society (WMS), taking place in Berlin, Germany, groundbreaking research on mitochondria-targeted medicine in military settings will be highlighted.

27 Sep 2024

World Lung Day 2024: Bedfont® Scientific Limited. Leads the Way in Asthma Care with the NObreath® FeNO Device

How the NObreath® device, recommended by NICE, is revolutionising asthma care this World Lung Day.

From NObreath 26 Sep 2024

COVID-19 causes lasting cognitive impairment tied to brain injury markers

Researchers found that COVID-19 patients experienced widespread cognitive deficits one year post-hospitalization, associated with elevated brain injury markers and reduced brain volume. Cognitive recovery plateaued over time, suggesting lasting impacts.

26 Sep 2024

New biomarker profiling enhances early detection of melanoma

Innovative research has unveiled promising advancements in melanoma detection, which could significantly enhance diagnosis and prognosis by identifying the disease at its earliest, most treatable stages.

25 Sep 2024

Study sheds light on mechanisms behind liver fibrosis and potential therapies

New research from the University of Pittsburgh School of Pharmacy sheds light on the processes that lead to liver fibrosis and suggests a novel treatment approach for this common and serious condition.

25 Sep 2024

Wrist-based sensors provide insights into sunlight’s impact on depression

Wrist-based activity sensors worn by individuals with depression and those without over the course of two weeks provided evidence for the relationship between daily sunlight exposure and physical activity, according to a study published September 25, 2024, in the open-access journal PLOS Mental Health by Oleg Kovtun and Sandra Rosenthal from Vanderbilt University, U.S.

25 Sep 2024

Plasma pTau181 predicts Alzheimer’s progression in real-world memory clinic patients

Researchers confirm plasma pTau181 is a strong predictor for Alzheimer's in patients with mild cognitive impairment, offering a less invasive diagnostic tool for early intervention.

20 Sep 2024

Anti-fibrotic drug shows promise in breast cancer

The most common breast cancer is HER2-negative, so called because it has low amounts of one of the proteins that contribute to tumor cell growth, HER2. Despite this common trait, the development of HER2-negative cancers varies among patients, so one goal is to be able to classify tumors in more detail and thus determine the best treatment for each case.

20 Sep 2024