Central Nervous System News and Research

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Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers.

1 Dec 2021

Packing the effects of exercise into a single pill for at-risk patients

Researchers from The Australian National University have identified unique molecular signals in the body that could hold the key to developing a supplement capable of administering the health benefits of exercise to patients incapable of physical activity.

1 Dec 2021

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

A human stroke drug, fast-tracked by the Food and Drug Administration and soon entering Phase 3 clinical trials, shows intriguing signs that it might also be a safe and powerful defense against Alzheimer's and other forms of dementia.

1 Dec 2021

Scientists identify new genes associated with familial Meniere's disease

A team of scientists from the University of Granada (UGR) and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research—led by Pablo Roman-Naranjo and Jose Antonio López-Escámez, researcher in charge of the Biohealth Research Institute in Granada (ibs.GRANADA)—has identified new genes associated with familial Meniere's disease.

1 Dec 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Study: About 1 in 100 COVID-19 patients likely develop central nervous system complications

The largest multi-institutional international study to date on brain complications of COVID-19 has found that approximately one in 100 patients hospitalized with COVID-19 will likely develop complications of the central nervous system.

29 Nov 2021

Researchers shed light on an important stage of early human embryogenesis for the first time

Scientists have shed light on an important stage of early embryonic development that has never been fully mapped out in humans before.

29 Nov 2021

New "image analysis pipeline" provides insight into how disease changes the body

A new "image analysis pipeline" is giving scientists rapid new insight into how disease or injury have changed the body, down to the individual cell.

24 Nov 2021

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Scientists investigate the neuroinvasive potential of SARS-CoV-2 and the role of tunneling nanotubes (TNTs) in spreading the infection to neighboring cells.

23 Nov 2021

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

In a study recently published on the bioRxiv preprint server, researchers attempted to further increase the scope of previous studies in examining SARS-CoV-2 infection of human CNS resident cells.

22 Nov 2021

Study sheds light on how residential distance from care impacts cancer diagnosis and survival

In a seemingly counterintuitive finding, young adults diagnosed with central nervous system (CNS) tumors might have better survival rates the farther they live from care.

21 Nov 2021

Researchers discover new type of cell that may help regulate heart rate

Researchers at the University of Notre Dame discovered a new type of cell in the heart that may help regulate heart rate, and could be an important key in understanding certain types of congenital heart defects and other diseases that involve the heart.

21 Nov 2021

Study may help predict genomic changes that may happen in advanced cancers based on therapy

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Novel long-read sequencing reveals complete repertoire of brain-expressed gene isoforms

New research led by the University of Exeter has shed light on the complexity of gene expression in the brain by characterizing the extent of isoform diversity in the human and mouse cortex, including the identification of novel isoforms of genes involved in diseases including Alzheimer's disease, autism and schizophrenia.

16 Nov 2021

Combination treatment improves overall survival for melanoma patients with brain metastases

Combination treatment with immune checkpoint inhibitors nivolumab and ipilimumab demonstrates overall survival for patients with melanoma that has spread to the brain, according to Phase II study results published today in The Lancet Oncology by researchers from The University of Texas MD Anderson Cancer Center.

11 Nov 2021

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

Northwestern University investigators have developed a new injectable therapy that harnesses "dancing molecules" to reverse paralysis and repair tissue after severe spinal cord injuries.

11 Nov 2021

COVID-19 and loss of sense of smell

A recent review examines the high susceptibility of the olfactory epithelium to SARS-CoV-2 infection.

9 Nov 2021

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

The current study looked at the impact of the virus on the CNS in the Syrian golden hamster, a useful animal model for COVID-19.

9 Nov 2021

CHOP-led network receives NIH-supported resources to unlock mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia (CHOP). The Children's Brain Tumor Network (CBTN), a multi-institutional brain tumor research program with its operations center housed at D3b, has collected tumor samples from patients all over the world.

3 Nov 2021

Central Nervous System News and Research

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

Packing the effects of exercise into a single pill for at-risk patients

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

Scientists identify new genes associated with familial Meniere's disease

Potentially neurotoxic SARS-CoV-2 protein fragments

Clinical drug research for the treatment of CNS and neurological disorders

Study: About 1 in 100 COVID-19 patients likely develop central nervous system complications

Researchers shed light on an important stage of early human embryogenesis for the first time

New "image analysis pipeline" provides insight into how disease changes the body

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

Study sheds light on how residential distance from care impacts cancer diagnosis and survival

Researchers discover new type of cell that may help regulate heart rate

Study may help predict genomic changes that may happen in advanced cancers based on therapy

Novel long-read sequencing reveals complete repertoire of brain-expressed gene isoforms

Combination treatment improves overall survival for melanoma patients with brain metastases

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

COVID-19 and loss of sense of smell

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

CHOP-led network receives NIH-supported resources to unlock mysteries behind pediatric brain tumors

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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